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Vacuette blood collection tubes

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Overview[edit]

A VACUETTE blood collection tube is a sterile plastic test tube with a colored cap showing the additive inside the tube which is evacuated, facilitating the drawing of a predetermined volume of liquid. VACUETTE tubes may contain additives designed to stabilize and preserve the specimen prior to analytical testing. These tubes have both colored caps showing the additive and color coded rings inside the cap which visually shows the draw volume of the tube.

The VACUETTE blood tube was the first plastic evacuated blood collection tube ever invented in 1985 by Greiner Bio-One International GmbH. Previously, blood collection tubes were mostly made of glass which caused potential contamination issues in hospitals and laboratories.

Types of VACUETTE Tubes[edit]

VACUETTE tubes may or may not have additives that are necessary for processing blood for testing in the medical laboratory.

The additives may include anticoagulants (EDTA, sodium citrate, heparin) or a gel with density between those of blood cells and blood plasma. Additionally, some tubes contain additives that preserve certain components of or substances within the blood, such as glucose. When a tube is centrifuged, the materials within are separated by density, with the blood cells sinking to the bottom and the plasma or serum accumulating at the top. Tubes containing gel can be easily handled and transported after centrifugation without the blood cells and serum mixing. The color of the tube caps indicate what additive, if any, is present in the tube. These colors are standardized across the preanalytic industry and the order in which they must be drawn to ensure test accuracy is referred to as the order of draw. The Clinical and Laboratory Standards Institute (CLSI) in its venipuncture standard (H3-A6) states that the following order of draw is recommended to avoid possible test result error due to additive carryover:

  1. Blood culture tube/vial
  2. Coagulation tube (eg, blue stopper)
  3. Serum tube with or without clot activator, with or without gel (eg, red stopper)
  4. Heparin tube with or without gel plasma separator (eg, green stopper)
  5. EDTA tube with or without gel separator (eg, lavender or pearl stopper)
  6. Glycolytic inhibitor ( eg, gray stopper)[1]

VACUETTE tubes also include tubes for trace elements testing and low volume tubes. Low volume tubes are used when smaller blood volumes are needed between 1 mL and 2.5 mL.

History and Culture[edit]

History[edit]

The VACUETTE blood collection tube is manufactured by Greiner Bio-One International GmbH. Greiner Bio-One International GmbH is a medical device and biotechnology plasticware manufacturing company that specializes in the manufacturing and sale of products for blood and specimen collection, biotechnology and scientific research, and OEM solutions. The headquarters is located in Kremsmünster, Austria with product sites in Austria, Germany, Hungary, the United States, Brazil, and Thailand with 26 global subsidiaries that employ more than 2,200 employees. Greiner Bio-One International GmbH is a part of the Greiner Group. The company's customers include health care institutions, science researchers, clinical laboratories, the pharmaceutical industry, dentist's offices and Physician's office labs. Greiner Bio-One was the first to manufacture the plastic petri dish (1963) and the first plastic evacuated blood collection tube with safety cap (1985).

Greiner Bio-One comprised of 3 divisions which includes:

• Preanalytics develops innovative collection systems for human and veterinary blood samples that make the flow of daily routine tasks in hospitals, laboratories or doctors' surgeries simpler and safer. In addition, the unit also provides customized, digital systems solutions (Greiner eHealth Technologies), which furnish greater efficiency and patient safety during the preanalytical process. This business segment focuses on phlebotomy or the process of drawing blood through a venipuncture.

• BioScience is technology partner to universities and research organizations, as well as to the diagnostics and pharmaceutical industries. The BioScience division supplies products for the analysis of cell cultures, microplates and DNA array applications.

The third business unit is Mediscan, a wholly-owned subsidiary of Greiner Bio-One International, which is also based in Kremsmünster (Austria) and is a supplier of expert services in the sterilization of medical products and food packaging, as well the functional improvement of plastics and semiconductors by means of ionizing radiation.As an Original Equipment Manufacturer (OEM), Greiner Bio-One provides solutions in the area of custom-made design developments and production processes for the life sciences and medical sectors.

Culture[edit]

VACUETTE blood collection tubes were used to preserve blood specimens from a frozen and fully formed wolly mammoth in Siberia for the purposes of laboratory testing.[2]


This article "Vacuette blood collection tubes" is from Wikipedia. The list of its authors can be seen in its historical and/or the page Edithistory:Vacuette blood collection tubes. Articles copied from Draft Namespace on Wikipedia could be seen on the Draft Namespace of Wikipedia and not main one.

  1. Ernst, Dennis (2011). "Is the Order of Draw a Tough Sell in Your Facility?". Phlebotomy.com. Retrieved July 19, 2018.
  2. "Flowing blood found in frozen woolly mammoth for first time". Metro. 2013-05-29. Retrieved 2018-07-19.