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Adrian Kee Keong Teo

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Adrian Kee Keong Teo
BornSingapore
🏳️ NationalitySingaporean
🎓 Alma materNational University of Singapore; University of Cambridge
💼 Occupation
Known forDisease modelling of diabetes using human pluripotent stem cells; cofounder of BetaLife Pte Ltd
🏅 AwardsA*STAR STAR Mentor Award (2023, 2024); JCI Ten Outstanding Young Persons (TOYP) – Medical Innovation (2019); Dr Susan Lim Outstanding Young Investigator Award (2018)

Adrian Kee Keong Teo is a Singaporean stem cell and diabetes researcher. He is currently the **Senior Principal Investigator** and **Deputy Director of the Cell & Molecular Therapy Division** at the Institute of Molecular and Cell Biology (**IMCB**), A*STAR.[1] He also holds academic appointments at the **National University of Singapore (NUS)** and is the scientific cofounder of **BetaLife Pte Ltd**, a biotechnology company developing stem cell–derived therapies for diabetes.[2]

Early life and education

Teo obtained his **B.Sc. (First Class Honours)** from the National University of Singapore (NUS).[2] He completed his **Ph.D. in Stem Cell Biology** at the University of Cambridge under Professor Ludovic Vallier, as an **A*STAR Graduate Scholar** and **Honorary Cambridge Commonwealth Trust Scholar**.[3] Following his doctoral studies, Teo conducted postdoctoral research at the **Joslin Diabetes Center**, Harvard Medical School, funded by a **JDRF Postdoctoral Fellowship**, focusing on pancreatic islet biology and diabetes.[3]

Career

After his postdoctoral training, Teo returned to Singapore to join the **Agency for Science, Technology and Research (A*STAR)**.[1] He is currently Senior Principal Investigator and Deputy Director of the Cell & Molecular Therapy Division at IMCB, and leads the **Stem Cell Diabetes Research Laboratory**.[1] He is also an **Associate Professor** in the Departments of Biochemistry and Medicine at NUS Yong Loo Lin School of Medicine.[4]

Teo is the **scientific cofounder of BetaLife Pte Ltd**, which develops clinical-grade stem cell–derived pancreatic beta cells for diabetes treatment.[5]

Research

Teo’s research focuses on **human pluripotent stem cells (hPSCs)** — including embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) — to model diabetes and understand beta cell development.[2] His laboratory studies **genetic and molecular mechanisms** that underlie pancreatic beta cell differentiation and dysfunction, with an aim to advance **cell replacement therapies** for diabetes.[1]

Teo has published widely on stem cell biology and regenerative medicine, including:

  • “New insights into human beta cell biology using human pluripotent stem cells” — Molecular Metabolism (2019).[6]
  • “Protocol for the generation of pancreatic and hepatic progenitors from human pluripotent stem cells” — STAR Protocols (2021).[7]
  • “Manufacturing clinical-grade human induced pluripotent stem cells” — Stem Cell Research & Therapy (2022).[8]

Awards and honors

  • **2024** – A*STAR Graduate Academy STAR Mentor Award[1]
  • **2023** – A*STAR Graduate Academy STAR Mentor Award[1]
  • **2023** – COVID-19 Resilience Medal, Government of Singapore[1]
  • **2022** – Graduate Mentor of the Year (GRAMAY) Award[1]
  • **2021** – Public Sector Transformation Award (A*STAR team award)[1]
  • **2019** – JCI Ten Outstanding Young Persons (TOYP) – Medical Innovation[1]
  • **2018** – Stem Cell Society Singapore Dr. Susan Lim Outstanding Young Investigator Award[1]
  • **2013** – JDRF Postdoctoral Fellowship[3]
  • **2011** – ISSCR Travel Award[3]
  • **2008** – Honorary Cambridge Commonwealth Trust Scholar[3]
  • **2008** – A*STAR Graduate Scholarship (A*STAR–Cambridge Partnership)[3]

Media coverage

Teo has been featured in several scientific and media articles:

  • “Weaponizing stem cells in the war on diabetes” — A*STAR Research feature (2023).[2]
  • “Opening the cellular gates to glucose” — A*STAR Research highlight (2022).[9]
  • “Singapore’s BetaLife develops stem cell cure for diabetes” — The Straits Times (2023).[10]

External links

References

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 "Adrian Teo – IMCB". A*STAR. Retrieved 12 October 2025.
  2. 2.0 2.1 2.2 2.3 "Weaponizing stem cells in the war on diabetes". A*STAR Research. Retrieved 12 October 2025.
  3. 3.0 3.1 3.2 3.3 3.4 3.5 "About Us – Adrian Teo Lab". Adrian Teo Laboratory. Retrieved 12 October 2025.
  4. "Associate Professor Adrian Teo". NUS Medicine. Retrieved 12 October 2025.
  5. "BetaLife Pte Ltd". BetaLife. Retrieved 12 October 2025.
  6. Teo, Adrian K. K. (2019). "New insights into human beta cell biology using human pluripotent stem cells". Molecular Metabolism. 32: 109–121. doi:10.1016/j.molmet.2019.11.011. PMC 7056928 Check |pmc= value (help). PMID 31926876.
  7. Teo, Adrian K. K. (2021). "Protocol for the generation of pancreatic and hepatic progenitors from human pluripotent stem cells". STAR Protocols. 2 (2): 100594. doi:10.1016/j.xpro.2021.100594. PMC 8209683 Check |pmc= value (help). PMID 34169288 Check |pmid= value (help).
  8. Teo, Adrian K. K. (2022). "Manufacturing clinical-grade human induced pluripotent stem cells". Stem Cell Research & Therapy. 13: 373. doi:10.1186/s13287-022-03077-1 (inactive 12 October 2025).
  9. "Opening the cellular gates to glucose". A*STAR Research. Retrieved 12 October 2025.
  10. "Singapore's BetaLife develops stem cell cure for diabetes". The Straits Times. 2023. Retrieved 12 October 2025.


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