Bradley Foerster
Bradley Foerster, M.D., Ph.D. is a U.S. trained and boarded radiologist with specialty training in neurobiology. He also has a doctoral degree in clinical investigation and is nationally recognized in the U.S. for his expertise in advanced imaging techniques to improve our understanding of amyotrophic lateral sclerosis (ALS), a fatal neurological disease.
Early life and education
Foerster was born in England, the son of a U.S. Lutheran missionary. At the age of five, the family moved to Caro, Michigan, a small town located in the thumb of Michigan. He completed a B.S.E. in chemical engineering at the University of Michigan, graduating summa cum laude (1992). After working in industry, he returned to the University of Michigan earning an M.D. (1999). He performed a residency in internal medicine at St. Joseph Mercy Hospital, Ann Arbor, MI (2002), a residency in radiology at the University of Michigan (2007), and a fellowship in neuroradiology at The Johns Hopkins Hospital (2009). After being awarded the American Roentgen Ray Scholar Award in 2009,[1] Foerster also earned a Ph.D. at the Johns Hopkins Bloomberg School of Public Health focusing his studies on developing an imaging test for ALS (2013).
- B.S.E. - Chemical Engineering, University of Michigan (1992)
- M.D. - University of Michigan (1999)
- Resident - Internal Medicine, St. Joseph Mercy Hospital, Ann Arbor, MI (2002)
- Resident - Diagnostic Radiology, University of Michigan (2007)
- Fellow - Neuroradiology, The Johns Hopkins Hospital (2009)
- Ph.D. - Clinical Investigation, Johns Hopkins Bloomberg School of Public Health (2013)
Career
Foerster has made contributions to medical science and clinical care in several critical areas, including ALS and chronic pain syndromes. He used new imaging techniques to measure levels of Gamma-Aminobutyric acid (GABA) in the brain in an effort to better understand disease processes.[citation needed]
Foerster was faculty briefly at The Johns Hopkins Hospital prior to being recruited back to the University of Michigan as an Assistant Professor of Radiology in 2009.[2]
Foerster has used advanced imaging methods to study physiologic changes in the central nervous system in chronic pain syndromes.[1][2][3][4] He was awarded a Veterans Administration (VA) Merit Grant award in 2012 to study chronic pain among the Veterans, which is a pervasive problem in this population. Based on the results from the research, he was awarded the Western Neuroradiology Society Gabriel Wilson Award in 2015.[3] Foerster has used advanced imaging methods to study physiologic changes in the central nervous system in chronic pain syndromes. Foerster has used advanced imaging methods to predict treatment responsiveness of fibromyalgia patients to transcranial direct stimulation therapy, which uses small electric currents to impact brain chemistry.[5]
In 2013, Foerster was named an Emerging Taubman Medical Scholar under the A. Alfred Taubman Medical Institute.[4] The institute was created to fund medical science research into a variety of different diseases including ALS, Alzheimer's disease, cancer, diabetes, and cardiovascular disease.
Foerster was also awarded a large NIH grant to develop a new test for ALS using advanced imaging techniques in 2014. He was the first to report alterations in both GABA and glutamate in the brain motor cortex in ALS.[6] Foerster has specifically focused on developing an imaging test to help diagnose ALS.[7][8][9][10] He has published other articles describing the use of multi-modal imaging techniques to better understand ALS.[11][12]
In 2016, Foerster was recognized for his academic accomplishments and was tenured as an Associate Professor of Radiology at the University of Michigan.
Foerster has also reported on alterations in GABA in the aging brain with mental processing capability declining along with GABA levels.[13][14]
Foerster has served as a reviewer on numerous publications and grant boards. He also trained numerous residents and fellows over the years. He has received other honors during his career including the RSNA Resident Research Award.[5] He has published over 40 peer reviewed articles and over 40 scientific presentations. He is the co-author of three chapters and author of one book.
References
- The University of Michigan Medical System
- "Taubman Institute awards grants to two UM researchers"[6]. Crain's Detroit Business. July 2 2013.
- ↑ Sundgren, Pia C.; Petrou, Myria; Harris, Richard E.; Fan, Xiaoying; Foerster, Bradley; Mehrotra, Neha; Sen, Ananda; Clauw, Daniel J.; Welsh, Robert C. (July 2007). "Diffusion-Weighted and Diffusion Tensor Imaging in Fibromyalgia Patients: A Prospective Study of Whole Brain Diffusivity, Apparent Diffusion Coefficient, and Fraction Anisotropy in Different Regions of the Brain and Correlation With Symptom Severity". Academic Radiology. 14 (7): 839–846. doi:10.1016/j.acra.2007.03.015. PMID 17574134.
- ↑ Petrou, M.; Harris, R.E.; Foerster, B.R.; Mclean, S.A.; Sen, A.; Clauw, D.J.; Sundgren, P.C. (May 2008). "Proton MR Spectroscopy in the Evaluation of Cerebral Metabolism in Patients with Fibromyalgia: Comparison with Healthy Controls and Correlation with Symptom Severity". American Journal of Neuroradiology. 29 (5): 913–918. doi:10.3174/ajnr.A0959. ISSN 0195-6108. PMID 18339723. Unknown parameter
|s2cid=ignored (help) - ↑ Foerster, B.R.; Petrou, M.; Harris, R.E.; Barker, P.B.; Hoeffner, E.G.; Clauw, D.J.; Sundgren, P.C. (November 2011). "Cerebral Blood Flow Alterations in Pain-Processing Regions of Patients with Fibromyalgia Using Perfusion MR Imaging". American Journal of Neuroradiology. 32 (10): 1873–1878. doi:10.3174/ajnr.A2614. ISSN 0195-6108. PMC 4337836. PMID 21868622.
- ↑ Harris, Richard E.; Napadow, Vitaly; Huggins, John P.; Pauer, Lynne; Kim, Jieun; Hampson, Johnson; Sundgren, Pia C.; Foerster, Bradley; Petrou, Myria; Schmidt-Wilcke, Tobias; Clauw, Daniel J. (December 2013). "Pregabalin Rectifies Aberrant Brain Chemistry, Connectivity, and Functional Response in Chronic Pain Patients". Anesthesiology. 119 (6): 1453–1464. doi:10.1097/ALN.0000000000000017. ISSN 0003-3022. PMID 24343290. Unknown parameter
|s2cid=ignored (help) - ↑ Cummiford, Chelsea M.; Nascimento, Thiago D.; Foerster, Bradley R.; Clauw, Daniel J.; Zubieta, Jon-Kar; Harris, Richard E.; DaSilva, Alexandre F. (December 2016). "Changes in resting state functional connectivity after repetitive transcranial direct current stimulation applied to motor cortex in fibromyalgia patients". Arthritis Research & Therapy. 18 (1): 40. doi:10.1186/s13075-016-0934-0. ISSN 1478-6362. PMC 4741001. PMID 26842987.
- ↑ Foerster, Bradley R.; Pomper, Martin G.; Callaghan, Brian C.; Petrou, Myria; Edden, Richard A. E.; Mohamed, Mona A.; Welsh, Robert C.; Carlos, Ruth C.; Barker, Peter B.; Feldman, Eva L. (2013-08-01). "An Imbalance Between Excitatory and Inhibitory Neurotransmitters in Amyotrophic Lateral Sclerosis Revealed by Use of 3-T Proton Magnetic Resonance Spectroscopy". JAMA Neurology. 70 (8): 1009–16. doi:10.1001/jamaneurol.2013.234. ISSN 2168-6149. PMC 4382938. PMID 23797905.
- ↑ Foerster, Bradley R.; Dwamena, Ben A.; Petrou, Myria; Carlos, Ruth C.; Callaghan, Brian C.; Pomper, Martin G. (September 2012). "Diagnostic Accuracy Using Diffusion Tensor Imaging in the Diagnosis of ALS". Academic Radiology. 19 (9): 1075–1086. doi:10.1016/j.acra.2012.04.012. PMC 4337857. PMID 22749050.
- ↑ Welsh, Robert C.; Jelsone-Swain, Laura M.; Foerster, Bradley R. (2013). "The Utility of Independent Component Analysis and Machine Learning in the Identification of the Amyotrophic Lateral Sclerosis Diseased Brain". Frontiers in Human Neuroscience. 7: 251. doi:10.3389/fnhum.2013.00251. ISSN 1662-5161. PMC 3677153. PMID 23772210.
- ↑ Foerster, Bradley R.; Dwamena, Ben A.; Petrou, Myria; Carlos, Ruth C.; Callaghan, Brian C.; Churchill, Cristina L.; Mohamed, Mona A.; Bartels, Claudia; Benatar, Michael; Bonzano, Laura; Ciccarelli, Olga (September 2013). "Diagnostic Accuracy of Diffusion Tensor Imaging in Amyotrophic Lateral Sclerosis". Academic Radiology. 20 (9): 1099–1106. doi:10.1016/j.acra.2013.03.017. PMC 4384461. PMID 23931423.
- ↑ Foerster, Bradley R.; Carlos, Ruth C.; Dwamena, Ben A.; Callaghan, Brian C.; Petrou, Myria; Edden, Richard A. E.; Mohamed, Mona A.; Welsh, Robert C.; Barker, Peter B.; Feldman, Eva L.; Pomper, Martin G. (February 2014). "Multimodal MRI as a diagnostic biomarker for amyotrophic lateral sclerosis". Annals of Clinical and Translational Neurology. 1 (2): 107–114. doi:10.1002/acn3.30. PMC 4212480. PMID 25356389.
- ↑ Foerster, Bradley R.; Feldman, Eva L. (2014-05-01). "A Brighter Future for Patients With Amyotrophic Lateral Sclerosis Through Imaging?". JAMA Neurology. 71 (5): 539–40. doi:10.1001/jamaneurol.2014.66. ISSN 2168-6149. PMID 24615393.
- ↑ Verstraete, Esther; Foerster, Bradley R. (April 2015). "Neuroimaging as a New Diagnostic Modality in Amyotrophic Lateral Sclerosis". Neurotherapeutics. 12 (2): 403–416. doi:10.1007/s13311-015-0347-9. ISSN 1933-7213. PMC 4404464. PMID 25791072.
- ↑ Simmonite, Molly; Carp, Joshua; Foerster, Bradley R.; Ossher, Lynn; Petrou, Myria; Weissman, Daniel H.; Polk, Thad A. (August 2019). "Age-Related Declines in Occipital GABA are Associated with Reduced Fluid Processing Ability". Academic Radiology. 26 (8): 1053–1061. doi:10.1016/j.acra.2018.07.024. PMC 6462248. PMID 30327163.
- ↑ Cassady, Kaitlin; Gagnon, Holly; Lalwani, Poortata; Simmonite, Molly; Foerster, Bradley; Park, Denise; Peltier, Scott J.; Petrou, Myria; Taylor, Stephan F.; Weissman, Daniel H.; Seidler, Rachael D. (February 2019). "Sensorimotor network segregation declines with age and is linked to GABA and to sensorimotor performance". NeuroImage. 186: 234–244. doi:10.1016/j.neuroimage.2018.11.008. PMC 6338503. PMID 30414983.
External links
- PubMed Publications
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