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Brain Preservation Foundation

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The Brain Preservation Foundation (BPF) is a nonprofit organization that runs a scientific challenge competition to encourage development of brain preservation technologies.[1] It also provides public education on topics such as the neural foundations of memory, brain scanning technologies, brain preservation, and mind uploading.

Mission[edit]

BPF’s mission is to promote scientific research into chemical brain preservation technologies that will allow the human brain’s connectome (and possibly more information) to be recovered.[2] The connectome is a comprehensive map of the neural connections in the brain, including the strength of those connections.The purpose of preserving a human brain connectome is to allow the mind uploading of the preserved mind if the technology is available in the long-run future.[3]

Brain Preservation Prizes[edit]

BPF developed two scientific challenge prizes.[4] The first prize is the small mammal brain preservation prize for the preservation of a small mammalian brain (e.g., a mouse brain) in a laboratory setting. The second prize is the large mammal brain preservation prize for the preservation of a large mammalian brain (e.g., a pig brain) using a surgical method that meets the medical standards necessary for it to be applied to a human patient in a hospital setting. The combined prize money available is more than $100,000[5] with the winner of the small mammal brain preservation prize getting 1/4 of that and the winner of the large mammal brain preservation prize getting the rest.

Competition for the Small Mammal Prize[edit]

Two scientific labs competed for the Small Mammal Prize.[6] One of the competitors was 21st Century Medicine, which created a new brain preservation method called Aldehyde-Stabilized Cryopreservation. This method was described in a 2015 article by Robert L. McIntyre and Gregory M. Fahy published in the peer-reviewed, scientific journal Cryobiology.[7]

Another competitor was Professor Shawn Mikula of the Max Planck Institute of Neurobiology, whose lab created a new brain preservation method called Brain-wide Reduced Osmium staining with Pyrogallol-mediated Amplification (BROPA). This method was described in a 2015 article by Shawn Mikula and Winfried Denk published in the peer-reviewed, scientific journal Nature Methods.[8]

Winner of the Small Mammal Prize[edit]

On February 9, 2016, BPF officially announced that 21st Century Medicine won the Small Mammal Brain Preservation Prize.[9][10][11][12][13][14][15][16][17][18]

Large Mammal Prize[edit]

The large mammal brain preservation prize is still available to be won. 21st Century Medicine is currently competing for this prize.[19]

References[edit]

  1. "Proposed: a Brain Preservation Technology Prize". Fight Aging!. 2010-03-24. Retrieved 2016-10-24.
  2. Adler, Jerry. "The Quest to Upload Your Mind Into the Digital Space". Smithsonian. Retrieved 2016-12-10.
  3. "Is An Identical Copy Of You, You?". NPR.org. Retrieved 2016-12-10.
  4. "The Brain Preservation Foundation: Better preservation through plastination". www.sentientdevelopments.com. Retrieved 2016-12-10.
  5. "Chemical brain preservation: how to live 'forever' — a personal view | KurzweilAI". www.kurzweilai.net. Retrieved 2016-12-10.
  6. "An Update from Competitors for the Brain Preservation Foundation's Technology Prize". Fight Aging!. 2012-03-12. Retrieved 2016-12-10.
  7. McIntyre, Robert L.; Fahy, Gregory M. (2015-12-01). "Aldehyde-stabilized cryopreservation". Cryobiology. 71 (3): 448–458. doi:10.1016/j.cryobiol.2015.09.003.
  8. Mikula, Shawn; Denk, Winfried (2015-06-01). "High-resolution whole-brain staining for electron microscopic circuit reconstruction". Nature Methods. 12 (6): 541–546. doi:10.1038/nmeth.3361. ISSN 1548-7091.
  9. "Newly invented Aldehyde-Stabilized Cryopreservation procedure wins Brain Preservation Prize". PRWeb. Retrieved 2016-10-20.
  10. Shermer, Michael. "Afterlife for Atheists". Scientific American. 314 (2): 73–73. doi:10.1038/scientificamerican0216-73.
  11. "Researchers Have Preserved An Entire Rabbit Brain". Popular Science. Retrieved 2016-10-20.
  12. reporter, Nina Golgowski Trends; Editor, The Huffington Post Jacqueline Howard Senior Science; Post, The Huffington (2016-02-11). "Cryogenically Frozen Rabbit Brain Hailed As Scientific First". The Huffington Post. Retrieved 2016-10-20.
  13. Dvorsky, George. "Brain Preservation Breakthrough Could Usher in a New Era in Cryonics". Gizmodo. Retrieved 2016-10-20.
  14. Times, Tech (2016-02-11). "Frozen Rabbit Brain Successfully Preserved Without Damage Through New Cryonics Method". Tech Times. Retrieved 2016-10-20.
  15. "Rabbit brain preserved by cryogenics for first time ever -". www.sciencerecorder.com. Retrieved 2016-10-20.
  16. Danigelis, Alyssa (2016-02-05). "Immortality Quest Aims to Preserve Brain 100 Years". Science. World. Exploration. Seek for yourself. Retrieved 2016-10-20.
  17. "Mammal brain successfully returned from cryopreservation for the first time". Newsweek. 2016-02-10. Retrieved 2016-10-20.
  18. Thomson, Helen. "Mammal brain frozen and thawed out perfectly for first time". New Scientist. Retrieved 2016-10-20.
  19. "Special Announcement: 21CM in the News 21st Century Medicine Wins the Brain Preservation Prize for Small Mammals". www.21cm.com. Retrieved 2016-12-10.


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