Brain Tumour Research
Brain Tumour Research is a UK charity dedicated to funding scientific research into brain tumours and campaigning for greater investment in research into the disease. In the financial year 2023/24, the charity delivered an income of £8.6 million, the highest income recorded to date..[1]
| Formation | 2009 |
|---|---|
| Type | Charitable Organisation |
| Registration no. |
|
| Purpose | Research and campaigning |
| Headquarters | Milton Keynes |
Region | United Kingdom |
Chief Executive | Dan Knowles |
| Website | https://braintumourresearch.org |
The charity works with and funds a network of experts in sustainable research at dedicated Centres of Excellence across the UK. The charity also focuses on influencing the Government and larger cancer charities to invest more nationally.
Launched by Brain Tumour Research in 2004[2], Brain Tumour Awareness Month takes place every March in the UK. Brain Tumour Awareness Month was supported by the House of Commons in March 2012[3].
Research
Brain Tumour Research provides funding to Brain Tumour Research Centres of Excellence at academic institutions, financing multi-disciplinary research with the aim of increasing knowledge of brain tumours at a molecular level, finding new targets for novel therapeutics and opening clinical trials.
Imperial College London
Brain Tumour Research funds a centre of excellence at Imperial College London, which is working to improve the diagnosis and treatment of adults with high-grade glioma, including glioblastoma, the most common primary high-grade brain tumour in adults[4].
The Institute of Cancer Research
The Institute of Cancer Research studies paediatric-type diffuse high-grade gliomas (PDHGG), a collection of brain tumours in children and young adults, which the charity argues have extremely poor clinical outcomes.[5] Brain Tumour Research awarded £2.5 million for the centre's opening in 2023.[6]
The research team is identifying, testing and validating new therapeutic targets for PDHGG, including diffuse intrinsic pontine glioma (DIPG), as well as developing new drug delivery methods. The Centre is generating the laboratory data needed to support the launch of new clinical trials.
Queen Mary University of London
Research financially supported at Queen Mary University of London[7][8] is developing personalised treatments for glioblastoma in adults and discovering new therapies for childhood brain tumours, including medulloblastoma, diffuse intrinsic pontine glioma (DIPG), and ependymoma.
Researchers at the centre published a study in 2021 regarding a weakness in a particular medulloblastoma subtype that could potentially be targeted with IP6 in combination in chemotherapy to kill tumour cells.[9]
University of Plymouth
Brain Tumour Research funds a centre of excellence at the University of Plymouth[10][11], which is working to improve the diagnosis and treatment of children and adults with low-grade brain tumours, including schwannoma, meningioma and glioma.
In 2025, the centre published a study regarding the protein Annexin A3 as a potential new treatment for meningioma. The research was led by Professor Oliver Hanemann, Director of the Brain Tumour Research Centre of Excellence in Plymouth.[12]
The Scottish Brain Tumour Research Centre of Excellence
The Scottish Brain Tumour Research Centre of Excellence is working on the development of new treatments for glioblastoma, with the aim of producing the evidence required to progress these treatments into clinical trials. The Scottish Centre is based at the Universities of Edinburgh and Glasgow and is funded in collaboration with Glasgow-based Beatson Cancer Charity.[13][14]
Funded Initiatives
Brain Tumour Research funds initiatives in partnership with other organisations and charities. These are:
- Patient Research Involvement Movement (PRIME) in partnership with brainstrust[15]
- Brain Tumour Research Novel Therapeutics Accelerator (BTR-NTA) in partnership with the Tessa Jowell Brain Cancer Mission (TJBCM)[16]
- BRAIN UK based at the University of Southampton[17]
- The University of Cardiff – Medical Research Council (MRC) Partnership
Campaigning
Brain Tumour Research campaigns to increase the UK national investment in research into brain tumours to £35 million a year.
Rare Cancers Bill
In 2025, Brain Tumour Research supported the Rare Cancers Bill[18], a Bill to make provision to incentivise research and investment into the treatment of rare types of cancer[19], sponsored by Scott Arthur MP. The Bill passed through the House of Commons in July 2025[20].
All-Party Parliamentary Group on Brain Tumours
Brain Tumour Research provides the secretariat of the All-Party Parliamentary Group on Brain Tumours (APPGBT), which was established in 2005 to raise awareness of the issues facing the brain tumour community in order to improve research, diagnosis, information, support, treatment and care outcomes[21].
Cross-Party Group on Brain Tumours
Brain Tumour Research holds the secretariat for the Cross-Party Group on Brain Tumours (CPGBT) in Scotland. This group was established in 2024 with Beatrice Wishart MSP as its chair.[22]
Patrons and Ambassadors
Brain Tumour Research is supported by a number of high-profile individuals, typically with their own connection to the cause, who help the charity raise awareness, amplify its campaigning and undertake their own fundraising.
The Charity’s Patrons are: broadcaster and business woman Sarah Beeny[23][24]; record producer, songwriter and TV personality Pete Waterman OBE[25]; multi-platinum selling recording artist Alfie Boe OBE[26]; model, actress and producer Caprice Bourret[27]; Antiques Roadshow expert Theo Burrell[13][28]; garden designer and TV presenter Danny Clarke[29]; and milliner Philip Treacy OBE[30]
Ambassadors for the Charity are: co-founder and former Chief Executive Sue Farrington Smith MBE, actor Charles Dale[31][32], Olympic athlete Sam Reardon, influencer and podcaster Abi Feltham[33][34] and actor Craig Russell[35][36]
References
- ↑ "Issuu Reader". issuu.com. Retrieved 2025-10-31.
- ↑ "Brain Tumour Awareness Month | Get Involved". Brain Tumour Research. Retrieved 2025-10-02.
- ↑ "BRAIN TUMOUR AWARENESS MONTH AND WEAR A HAT DAY - Early Day Motions - UK Parliament". edm.parliament.uk. Retrieved 2025-10-31.
- ↑ Wen, Patrick Y; Weller, Michael; Lee, Eudocia Quant; Alexander, Brian M; Barnholtz-Sloan, Jill S; Barthel, Floris P; Batchelor, Tracy T; Bindra, Ranjit S; Chang, Susan M; Chiocca, E Antonio; Cloughesy, Timothy F; DeGroot, John F; Galanis, Evanthia; Gilbert, Mark R; Hegi, Monika E (2020-08-17). "Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions". Neuro-Oncology. 22 (8): 1073–1113. doi:10.1093/neuonc/noaa106. ISSN 1522-8517. PMC 7594557 Check
|pmc=value (help). PMID 32328653 Check|pmid=value (help). - ↑ "Children's cancers mortality statistics". Cancer Research UK. 2015-05-14. Retrieved 2025-10-31.
- ↑ "Charity funding could help establish new clinical trials for deadliest of all childhood cancers". www.icr.ac.uk. Retrieved 2025-10-31.
- ↑ "£1.5 million to fight brain tumours". Barts Charity. 2019-01-10. Retrieved 2025-10-31.
- ↑ "New brain tumour research Centre of Excellence is unveiled at QMUL". Queen Mary University of London. 2014-10-23. Retrieved 2025-10-02.
- ↑ Badodi, Sara; Pomella, Nicola; Zhang, Xinyu; Rosser, Gabriel; Whittingham, John; Niklison-Chirou, Maria Victoria; Lim, Yau Mun; Brandner, Sebastian; Morrison, Gillian; Pollard, Steven M.; Bennett, Christopher D.; Clifford, Steven C.; Peet, Andrew; Basson, M. Albert; Marino, Silvia (2021-04-12). "Inositol treatment inhibits medulloblastoma through suppression of epigenetic-driven metabolic adaptation". Nature Communications. 12 (1): 2148. Bibcode:2021NatCo..12.2148B. doi:10.1038/s41467-021-22379-7. ISSN 2041-1723. PMC 8042111 Check
|pmc=value (help). PMID 33846320 Check|pmid=value (help). - ↑ "Brain Tumour Research". University of Plymouth. Retrieved 2025-10-31.
- ↑ "Historic Brain Tumour Research partnership launched". University of Plymouth. 2014-11-20. Retrieved 2025-10-02.
- ↑ Shah, Maryam; Akther, Yeasmin; Adams, Claire L.; Banton, Matthew C.; Sharma, Vikram; Ercolano, Emanuela; Hilton, David A.; Kurian, Kathreena M.; Laraba, Liyam; Woznica, Waldemar; Parkinson, David Bryan; de Assis, Leandro José; Hanemann, Clemens Oliver (July 2025). "Integrated proteomic and targeted Next Generation Sequencing reveal relevant heterogeneity in lower-grade meningioma and ANXA3 as a new target in NF2 mutated meningiomas". eBioMedicine. 117. doi:10.1016/j.ebiom.2025.105814. ISSN 2352-3964. PMC 12278414 Check
|pmc=value (help). PMID 40562609 Check|pmid=value (help). Unknown parameter|article-number=ignored (help) - ↑ 13.0 13.1 "New brain tumour research centre gives people 'tangible hope', says Theo". East Lothian Courier. 2025-02-08. Retrieved 2025-10-02.
- ↑ "New Research Centre in Scotland brings hope to brain cancer patients | Institute for Regeneration and Repair". Institute for Regeneration and Repair. 2025-01-30. Retrieved 2025-10-31.
- ↑ "PRIME - get involved with brain tumour research at brainstrust". Brainstrust, brain tumour charity. 2025-09-18. Retrieved 2025-10-02.
- ↑ "#Brain Tumour Research Novel Therapeutics Accelerator (BTR-NTA) | Tessa Jowell Brain Cancer Mission (TJBCM)". Tessa Jowell Brain Cancer Mission (TJBCM) | Calling for action to improve brain tumour treatment, research and survival. 2022-04-22. Retrieved 2025-10-02.
- ↑ "BRAIN UK". brain-uk.org. Retrieved 2025-10-02.
- ↑ Post, Hippocratic (2025-03-13). "MPs to debate Rare Cancers Bill". The Hippocratic Post. Retrieved 2025-10-31.
- ↑ "Rare Cancers Bill - Parliamentary Bills - UK Parliament". bills.parliament.uk. Retrieved 2025-10-02.
- ↑ "'I Can Actually Say I'm Doing Something About This': Scott Arthur On His Rare Cancers Bill". Politics Home. 2025-10-20. Retrieved 2025-10-31.
- ↑ "House of Commons - Register Of All-Party Parliamentary Groups as at 28 March 2025: Brain Tumours". publications.parliament.uk. Retrieved 2025-10-02.
- ↑ "Brain Tumours". www.parliament.scot. Retrieved 2025-10-02.
- ↑ Cook, Rebecca (2021-03-22). "Sarah Beeny shares experience of losing mum at virtual event". Somerset Live. Retrieved 2025-10-02.
- ↑ "Sarah Beeny becomes cancer charity patron after death of mother and stepmother". York Press. 2025-03-13. Retrieved 2025-10-02.
- ↑ "Pete Waterman becomes patron of Brain Tumour Research in honour of son Paul". The Independent. 2024-11-13. Retrieved 2025-10-02.
- ↑ Clarke, Naomi (2024-07-07). "Alfie Boe launches rose for brain tumour charity in memory of his late father". The Standard. Retrieved 2025-10-02.
- ↑ "Exclusive: How a health scare led Caprice to change her lifestyle and support a special cause". HELLO!. 2024-05-13. Retrieved 2025-10-02.
- ↑ Media, P. A. (2025-07-16). "TV star with brain tumour joins squats challenge to raise funds to find cure". STV News. Retrieved 2025-10-02.
- ↑ Vesty, Helena (2024-02-06). "'We don't want families to endure the same devastation we have'". Manchester Evening News. Retrieved 2025-10-02.
- ↑ Lake, Howard (2016-05-19). "Fenwick supports Brain Tumour Research with designer hat auction". UK Fundraising. Retrieved 2025-10-02.
- ↑ "Actor Charles Dale to visit Somerset as part of 100 motorcycle cafe challenge". Chard & Ilminster News. 2025-05-31. Retrieved 2025-10-02.
- ↑ "Emmerdale star to stop off in Hampshire during motorcycle fundraiser". Hampshire Chronicle. 2025-05-26. Retrieved 2025-10-02.
- ↑ 161385360554578 (2025-03-21). "Coffee addict, 37, thought nothing of headaches until aggressive cancer found". The Sun. Retrieved 2025-10-02.
- ↑ Shaw, Neil (2025-03-25). "Woman given 15 years to live laughs and says it's 'an entire second life'". The Mirror. Retrieved 2025-10-02.
- ↑ "Protein film actor Craig Russell 'lucky' to see film after brain tumour". BBC News. 2025-06-22. Retrieved 2025-10-02.
- ↑ "Lime-sized tumour 'deformed' Hollyoaks actor's skull". The Independent. 2025-06-26. Retrieved 2025-10-02.
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