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Build-a-Cell

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The Build-a-Cell Initiative.
The Build-a-Cell Initiative.

The Build-a-Cell Initiative, An Open Community Considering & Advancing the Construction of Synthetic Cells, is a large-scale international collaborative research project aimed at construction of synthetic living cell. The Initiative was formed during the Build-a-Cell Workshop #1 in July 2017[1][2] by Drew Endy, Richard Murray, John Glass and Kate Adamala. The Initiative takes advantage of tools of traditional molecular biology and synthetic biology, like artificial gene synthesis and liposome technologies. The initiative combines efforts of bottom-up synthetic biology studies and top-down natural cell minimization of the Mycoplasma laboratorium community.[3]

The members of the Build-a-Cell come from over 60 academic groups in 15 countries.[4] The initiative is funded by the National Science Foundation Research Coordination Network.[5]

Researchers and policy analyzers expect that the ability to engineer an artificial living cell will result in many scientific advances, especially in biomedicine[6] and basic research[7][8]

The Build-a-Cell organizes bi-annual international workshops.


See also[edit]

References[edit]

  1. "Build-a-Cell Workshop #1". Build-a-Cell. Retrieved 4 Dec 2019.
  2. "From chemicals to life: Scientists try to build cells from scratch". Statnews. Retrieved 4 Dec 2019.
  3. Callaway, Ewen (2016). "'Minimal' cell raises stakes in race to harness synthetic life". Nature. 531 (7596): 557–558. Bibcode:2016Natur.531..557C. doi:10.1038/531557a. ISSN 0028-0836. PMID 27029256.
  4. "Members of Build-a-Cell". Build-a-Cell. Retrieved 4 Dec 2019.
  5. "Award Abstract 1901145 RCN Build-a-Cell: An Open Community Considering & Advancing the Construction of Synthetic Cells". National Science Foundation. Retrieved 4 Dec 2019.
  6. "Why should we personalize medicine?". medium.com. Retrieved 4 Dec 2019.
  7. Yewdall, N. Amy; Mason, Alexander F.; van Hest, Jan C. M. (2018). "The hallmarks of living systems: towards creating artificial cells". Interface Focus (8). doi:10.1098/rsfs.2018.0023. PMID 30443324.
  8. Elowitz, M; Lim, WA (2010). "Build life to understand it". Nature (16). doi:10.1038/468889a. PMC 3068207. PMID 21164460.

Further reading[edit]


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