Christoph W Müller
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Christoph W Müller | |
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File:Christoph Muller.pngChristoph_Muller.png | |
Born | |
🎓 Alma mater | University of Freiburg (PhD) |
💼 Occupation | |
🏅 Awards |
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🌐 Website | https://www.embl.org/groups/mueller/ |
Christoph W Müller is a German structural biologist. He is the Head of the Structural and Computational Biology Unit at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany.[1][2]
Education[edit]
Müller studied chemistry at the University of Freiburg from 1981 to 1986. He received his PhD in x-ray crystallography and biochemistry in 1991 from the University of Freiburg.
Career and Research[edit]
Müller held postdoctoral fellowships at the University of Freiburg, and Harvard University. He was appointed Group leader in structural biology at EMBL Grenoble in 1995 and Deputy Head of EMBL Grenoble in 2000. Müller has been the Head of the Structural and Computational Biology Unit at EMBL Heidelberg since 2007. Müller’s research uses cryo-electron microscopy, x-ray crystallography, biophysical and biochemical approaches to learn about the molecular mechanisms of transcription regulation in eukaryotes where DNA is packaged into chromatin. His areas of research comprise DNA recognition by eukaryotic transcription factors,[3], molecular mechanisms of nuclear transport,[4] and the structural basis of DNA-dependent RNA transcription initiation, elongation and termination by RNA polymerase I and III.[5][6]
Affiliations and Honours[edit]
In 2005, Müller was elected as a Member of the European Molecular Biology Organisation (EMBO).[7][8] In 2013, he obtained an European Research Council Advanced Investigator Grant.[9] He has been a Member of Academia Europaea since 2018.[10] Since 2019 he has sat on the Instruct-ERIC Council.[11] In 2014 he was invited to join the Scientific Advisory Board for the French Infrastructure for Integrated Structural Biology (FRISBI).[12][13] Further more he has twice held (2019, 2015) the Panel Chair position of the ATIP-Avenir programme, a partnership between the French National Center for Scientific Research (CNRS) and Inserm.[14] In 2017 he was appointed as a member of Scientific Advisory Board for the Novo Nordisk Foundation Centre for Protein Research.[15] In 2003 he was awarded the Steinhofer-award from the Steinhofer Foundation, University of Freiburg.
References[edit]
- ↑ Christoph W Müller's publications indexed by the Scopus bibliographic database. (subscription required)
- ↑ Christoph W Müller publications from Europe PubMed Central
- ↑ Becker, Stefan; Groner, Bernd; Müller, Christoph W. (July 1998). "Three-dimensional structure of the Stat3β homodimer bound to DNA". Nature. 394 (6689): 145–151. doi:10.1038/28101.
- ↑ Cingolani, Gino; Petosa, Carlo; Weis, Karsten; Müller, Christoph W. (May 1999). "Structure of importin-β bound to the IBB domain of importin-α". Nature. 399 (6733): 221–229. doi:10.1038/20367.
- ↑ Girbig, Mathias; Misiaszek, Agata D.; Müller, Christoph W. (September 2022). "Structural insights into nuclear transcription by eukaryotic DNA-dependent RNA polymerases". Nature Reviews Molecular Cell Biology. 23 (9): 603–622. doi:10.1038/s41580-022-00476-9.
- ↑ Seifert-Davila, Wolfram; Girbig, Mathias; Hauptmann, Luis; Hoffmann, Thomas; Eustermann, Sebastian; Müller, Christoph W. (7 July 2023). "Structural insights into human TFIIIC promoter recognition". Science Advances. 9 (27). doi:10.1126/sciadv.adh2019.
- ↑ "Find people in the EMBO Communities". people.embo.org.
- ↑ "EMBO elects 40 top researchers to its membership" (PDF). EMBO.org.
- ↑ "ERC Advanced Grants 2013 Results" (PDF). www.erc.europa.eu/.
- ↑ "Academy of Europe: Müller Christoph". www.ae-info.org.
- ↑ "Instruct-ERIC Governance". www.instruct-eric.org.
- ↑ "French Infrastructure for Intergrated Structural Biology". www.frisbi.eu/.
- ↑ "FRISBI Governance structure" (PDF). frisbi.eu.
- ↑ "Inserm". www.inserm.fr.
- ↑ "Members of the Scientific Advisory Board". cpr.ku.dk.
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