Cristopher M. Niell
| Cristopher M. Niell | |
|---|---|
| Born | |
| 🎓 Alma mater | Stanford University (B.S., Ph.D.) |
| 💼 Occupation | |
| 🏅 Awards | NIH Director's New Innovator Award (2012), Searle Scholar (2012), Alfred P. Sloan Research Fellowship (2012) |
Cristopher Niell is an American neuroscientist at the University of Oregon[1] known for establishing the mouse as a model organism for the study of mammalian vision.[2][3][4][5] His research has revealed fundamental principles of how the brain processes the visual world: that an animal's own movements actively shape cortical visual responses, with locomotion more than doubling the firing rate of neurons in primary visual cortex,[6][7] and that each time an animal moves its eyes to look at something new, cortical neurons respond in a temporal sequence ordered from coarse to fine, with neurons sensitive to broad, low spatial frequency structure firing first and those tuned to fine detail following, a process conserved across mice and primates that reflects how the brain builds a coherent visual percept with each glance.[8] He and his team have further pioneered the study of vision in the context of natural behaviors including prey capture,[9] and have extended their research to the octopus as a comparative model, motivated by the fact that despite having eyes remarkably similar to vertebrates, octopuses evolved their visual systems entirely independently and process visual information in ways that are fundamentally different from mammals.[10]
References
- ↑ "Niell Lab – People". University of Oregon. Retrieved 2024-01-01.
- ↑ Niell, CM; Stryker, MP (2008). "Highly selective receptive fields in mouse visual cortex". Journal of Neuroscience. 28 (30): 7520–36. doi:10.1523/JNEUROSCI.0623-08.2008. PMC 3040721. PMID 18650330.
- ↑ Huberman, AD; Niell, CM (2011). "What can mice tell us about how vision works?". Trends in Neurosciences. 34 (9): 464–73. doi:10.1016/j.tins.2011.05.001. PMC 3371366. PMID 21700346.
- ↑ Baker, M (2013). "Neuroscience: Through the eyes of a mouse". Nature. 502 (7470): 156–158. Bibcode:2013Natur.502..156B. doi:10.1038/502156a. PMID 24108031.
- ↑ "Cris Niell's pioneering research into how mice see featured in Nature". University of Oregon. October 10, 2013.
- ↑ Niell, CM; Stryker, MP (2010). "Modulation of visual responses by behavioral state in mouse visual cortex". Neuron. 65 (4): 472–9. doi:10.1016/j.neuron.2010.01.033. PMC 3184003. PMID 20188652.
- ↑ Cepelewicz, Jordana (November 7, 2019). "'Noise' in the Brain Encodes Surprisingly Important Signals". Quanta Magazine.
- ↑ Parker, PRL; Martins, DM; Leonard, ESP (2023). "A dynamic sequence of visual processing initiated by gaze shifts". Nature Neuroscience. 26 (12): 2192–2202. doi:10.1038/s41593-023-01481-7. PMID 37996524 Check
|pmid=value (help). - ↑ Hoy, JL; Bishop, HI; Niell, CM (2019). "Defined cell types in superior colliculus make distinct contributions to prey capture behavior in the mouse". Current Biology. 29 (23): 4130–4138. Bibcode:2019CBio...29E4130H. doi:10.1016/j.cub.2019.10.017. PMC 6899177 Check
|pmc=value (help). PMID 31761701. - ↑ DiCarlo, Gemma (August 2, 2023). "University of Oregon research offers a window into how octopuses see". OPB.
Category:American neuroscientists Category:University of Oregon faculty Category:Stanford University alumni Category:Living people Category:Year of birth missing (living people)
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