Cyclobutylaminergolide
From EverybodyWiki Bios & Wiki
\-_-____*&*&(^(&(^*&
| File:CyclobutylaminergolideJPG.jpg | |
| File:Cyclobutylaminergolide3D- - ***.png | |
| Clinical data | |
|---|---|
| Trade names | Aminergolide |
| Pregnancy category |
|
| Routes of administration | Oral, Inhalational, Intramuscular, Intravenous |
| Legal status | |
| Legal status |
|
| Pharmacokinetic data | |
| Bioavailability | 100% (Oral, IV) |
| Metabolism | Extensively liver-mediated |
| Elimination half-life | 666.981h - 1316.718h +/- 0.918 weeks |
| Identifiers | |
| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}} |
| Site | Binding Affinity (pKi)
(*)=pKd (')=Ki |
Intrinsic Activity
(Emax) |
Action |
|---|---|---|---|
| D2 | 0.31 fM (*) | +3137% | Hyperagonist |
| D3 | 0.1 fM | +3137% | Hyperagonist |
| D4 | 0.1 fM (') | +3137% | Hyperagonist |
| 5HT1 | 0.06 fM (*) | +3137% | Hyperagonist |
| 5HT2A | 0.3167 fM | +1669% (G-Protein) | Superagonist |
| 5HT2B | 0.01716 fM | +3137% | Pseudoirreversible
Hyperagonist |
| 5HT2C | 0.0187 fM (') | +1669% | Pseudoirreversible
Superagonist |
| 5HT6 | 0.08719 fM | +1669% | Pseudoirreversible
Superagonist |
| TAAR1 | 0.45779 pM | +103% | Full Agonist |
| M1 | 0.918 pM (') | +1669% | Hyperagonist |
| M5 | 0.03917 nM | +100% | Full Agonist |
This article "Cyclobutylaminergolide" is from Wikipedia. The list of its authors can be seen in its historical and/or the page Edithistory:Cyclobutylaminergolide. Articles copied from Draft Namespace on Wikipedia could be seen on the Draft Namespace of Wikipedia and not main one.
