Deutivacaftor

Deutivacaftor

Clinical data
Routes of administration	By mouth
Identifiers
IUPAC name N-(2,4-Di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide
CAS Number	1413431-07-8 Y
PubChem CID	71470491
DrugBank	DB15141 Y
ChemSpider	64853784 Y
UNII	SHA6U5FJZL
KEGG	D11423 N
ChEBI	CHEBI:66901 Y
ChEMBL	ChEMBL2010601
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C24H28N2O3
Molar mass	392.499 g·mol−1
3D model (JSmol)	Interactive image
SMILES [2H]C([2H])([2H])C(c1cc(C(C)(C)C)c(NC(=O)c2c[nH]c3ccccc3c2=O)cc1O)(C([2H])([2H])[2H])C([2H])([2H])[2H]
InChI InChI=1S/C24H28N2O3/c1-23(2,3)16-11-17(24(4,5)6)20(27)12-19(16)26-22(29)15-13-25-18-10-8-7-9-14(18)21(15)28/h7-13,27H,1-6H3,(H,25,28)(H,26,29)/i4D3,5D3,6D3 Y[chembl] Key:PURKAOJPTOLRMP-ASMGOKTBSA-N Y[chembl]

Deutivacaftor is a deuterated analogue of the cystic fibrosis drug ivacaftor. It is sold only as part of the combination product vanzacaftor/tezacaftor/deutivacaftor, sold under the brand name Alyftrek. It acts as a CFTR potentiator.

References

Template:Other respiratory system products

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