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Differentially expressed gene

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Differentially expressed gene (or DEG) is a collective term used for subsets of genes that undergo expressional changes (this most commonly refers to altered mRNA levels.[1]) under specific experimental conditions in a given cell or tissue type. These conditions include, but are not limited to: time/differentiation[2][3], pharmacological treatments[4], immune response[5], activation status[6]

References

  1. Takács, Roland; Vágó, Judit; Póliska, Szilárd; Pushparaj, Peter Natesan; Ducza, László; Kovács, Patrik; Jin, Eun-Jung; Barrett-Jolley, Richard; Zákány, Róza; Matta, Csaba (2023-05-08). "The temporal transcriptomic signature of cartilage formation". Nucleic Acids Research. 51 (8): 3590–3617. doi:10.1093/nar/gkad210. ISSN 1362-4962. PMC 10164575 Check |pmc= value (help). PMID 36987858 Check |pmid= value (help).
  2. Takács, Roland; Vágó, Judit; Póliska, Szilárd; Pushparaj, Peter Natesan; Ducza, László; Kovács, Patrik; Jin, Eun-Jung; Barrett-Jolley, Richard; Zákány, Róza; Matta, Csaba (2023-05-08). "The temporal transcriptomic signature of cartilage formation". Nucleic Acids Research. 51 (8): 3590–3617. doi:10.1093/nar/gkad210. ISSN 1362-4962. PMC 10164575 Check |pmc= value (help). PMID 36987858 Check |pmid= value (help).
  3. Khan, Sher Afzal; Eggleston, Heather; Myles, Kevin M.; Adelman, Zach N. (2019-07-09). "Differentially and Co-expressed Genes in Embryo, Germ-Line and Somatic Tissues of Tribolium castaneum". G3 (Bethesda, Md.). 9 (7): 2363–2373. doi:10.1534/g3.119.400340. ISSN 2160-1836. PMC 6643895 Check |pmc= value (help). PMID 31113821.
  4. Won, Hong-Hee; Kim, Suk Ran; Bang, Oh Young; Lee, Sang-Chol; Huh, Wooseong; Ko, Jae-Wook; Kim, Hyung-Gun; McLeod, Howard L.; O'Connell, Thomas M.; Kim, Jong-Won; Lee, Soo-Youn (February 2012). "Differentially expressed genes in human peripheral blood as potential markers for statin response". Journal of Molecular Medicine (Berlin, Germany). 90 (2): 201–211. doi:10.1007/s00109-011-0818-3. ISSN 1432-1440. PMID 21947165. Unknown parameter |s2cid= ignored (help)
  5. Qi, Lina; Ye, Chenyang; Zhang, Ding; Bai, Rui; Zheng, Shu; Hu, Wangxiong; Yuan, Ying (2021). "The Effects of Differentially-Expressed Homeobox Family Genes on the Prognosis and HOXC6 on Immune Microenvironment Orchestration in Colorectal Cancer". Frontiers in Immunology. 12: 781221. doi:10.3389/fimmu.2021.781221. ISSN 1664-3224. PMC 8688249 Check |pmc= value (help). PMID 34950145 Check |pmid= value (help).
  6. Wang, Huaibin; Wang, Miaomiao; Xiao, Kun; Zhang, Xu; Wang, Peng; Xiao, Shuyu; Qi, Huisheng; Meng, Lijun; Zhang, Xiujun; Shen, Fuhai (2019). "Bioinformatics analysis on differentially expressed genes of alveolar macrophage in IPF". Experimental Lung Research. 45 (9–10): 288–296. doi:10.1080/01902148.2019.1680765. ISSN 1521-0499. PMID 31762326. Unknown parameter |s2cid= ignored (help)


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