Eµ-Pim1 mouse
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The Eμ-pim1 mouse is a transgenic rodent developed in 1989, which contains the pim-1 oncogene, which is expressed at higher levels in their lymph nodes and other lymphoid compartments, in order to predispose them to the development of T-cell lymphomas. They are attractive candidates for short-term carcinogenicity tests, such as to ionizing radiation and chemical carcinogens.
Reference[edit]
Coen F. et al. - Evaluation of the Eμ-pim-1 Transgenic Mouse Model for Short-Term Carcinogenicity Testing. Toxicologic Pathology, 26 (6): 750-756, 1998.
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