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Eidogen-Sertanty, Inc.

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Eidogen-Sertanty, Inc.
ISIN🆔
Industry
Founded 📆2003; 21 years ago (2003)
Founder 👔Steven Muskal (CEO)
Headquarters 🏙️, ,
United States
Area served 🗺️
Members
Number of employees
🌐 Websitewww.eidogen-sertanty.com
📇 Address
📞 telephone

Eidogen-Sertanty is an American software company founded in 2003. Eidogen-Sertanty provides software[1] and content[2] and engages in collaborative services[3] which accelerate the drug discovery process.

Databases[edit]

  • Kinase Knowledgebase (KKB)[4][5] - Database of kinase structure-activity data.
  • Oncology Knowledgebase (OKB) - Database of oncological structure-activity data.
  • Target Informatics Platform (TIP)[6][7][8] - Protein structural informatics system and knowledgebase.

Sertanty and Eidogen-Sertanty[edit]

In 2005, Sertanty acquired Eidogen and was renamed to Eidogen-Sertanty, Inc[9]

See also[edit]

References[edit]

  1. Schürer, Stephan C.; Tyagi, Prashant; Muskal, Steven M. (1 March 2005). "Prospective Exploration of Synthetically Feasible, Medicinally Relevant Chemical Space". Journal of Chemical Information and Modeling. 45 (2): 239–248. doi:10.1021/ci0496853. PMID 15807484.Vidović, Dušica; Muskal, Steven M.; Schürer, Stephan C. (21 December 2012). "Novel Kinase Inhibitors by Reshuffling Ligand Functionalities Across the Human Kinome". Journal of Chemical Information and Modeling. 52 (12): 3107–3115. doi:10.1021/ci3003842. PMID 23121521.Muskal, Steven M.; Jha, Sanjiv Kumar; Kishore, M. Phani; Tyagi, Prashant (1 September 2003). "A Simple and Readily Integratable Approach to Toxicity Prediction". Journal of Chemical Information and Computer Sciences. 43 (5): 1673–1678. doi:10.1021/ci034080c. PMID 14502502.
  2. "Chemical Information Sources/SIRCh/Cheminformatics/Companies and Independent Institutions - Wikibooks, open books for an open world". en.wikibooks.org.
  3. Muskal, Steven M.; Sliman, Joe; Kokai-Kun, John; Pimentel, Mark; Wacher, Vince; Gottlieb, Klaus (22 June 2016). "Lovastatin lactone may improve irritable bowel syndrome with constipation (IBS-C) by inhibiting enzymes in the archaeal methanogenesis pathway". F1000Research. 5: 606. doi:10.12688/f1000research.8406.3. PMC 4909102. PMID 27347377.Patel, Priya; Patel, Hiteshi; Vekariya, Dhara; Joshi, Chinmayi; Patel, Pooja; Muskal, Steven; Kothari, Vijay (5 July 2019). "Sonic Stimulation and Low Power Microwave Radiation Can Modulate Bacterial Virulence Towards Caenorhabditis elegans". Anti-Infective Agents. 17 (2): 150–162. doi:10.2174/2211352516666181102150049. Unknown parameter |s2cid= ignored (help)
  4. Sharma, Rajan; Schürer, Stephan C.; Muskal, Steven M. (26 October 2016). "High quality, small molecule-activity datasets for kinase research". F1000Research. 5: 1366. doi:10.12688/f1000research.8950.1. PMC 4943296. PMID 27429748.
  5. Hu, Jiaming; Allen, Bryce K.; Stathias, Vasileios; Ayad, Nagi G.; Schürer, Stephan C. (January 2024). "Kinome-Wide Virtual Screening by Multi-Task Deep Learning". International Journal of Molecular Sciences. 25 (5): 2538. doi:10.3390/ijms25052538. PMC 10932040 Check |pmc= value (help). PMID 38473785 Check |pmid= value (help).Allen, Bryce K.; Mehta, Saurabh; Ember, Stewart W. J.; Schonbrunn, Ernst; Ayad, Nagi; Schürer, Stephan C. (24 November 2015). "Large-Scale Computational Screening Identifies First in Class Multitarget Inhibitor of EGFR Kinase and BRD4". Scientific Reports. 5: 16924. Bibcode:2015NatSR...516924A. doi:10.1038/srep16924. PMC 4657038. PMID 26596901.Essegian, Derek J.; Chavez, Valery; Khurshid, Rabia; Merchan, Jaime R.; Schürer, Stephan C. (26 May 2023). "AI-Assisted chemical probe discovery for the understudied Calcium-Calmodulin Dependent Kinase, PNCK". PLOS Computational Biology. 19 (5): e1010263. Bibcode:2023PLSCB..19E0263E. doi:10.1371/journal.pcbi.1010263. PMC 10249896 Check |pmc= value (help). PMID 37235579 Check |pmid= value (help). Schürer, Stephan C.; Muskal, Steven M. (28 January 2013). "Kinome-wide Activity Modeling from Diverse Public High-Quality Data Sets". Journal of Chemical Information and Modeling. 53 (1): 27–38. doi:10.1021/ci300403k. PMC 3569091. PMID 23259810. Nicola, George; Kufareva, Irina; Ilatovskiy, Andrey V.; Abagyan, Ruben (March 2020). "Druggable exosites of the human kino-pocketome". Journal of Computer-Aided Molecular Design. 34 (3): 219–230. Bibcode:2020JCAMD..34..219N. doi:10.1007/s10822-019-00276-y. PMC 7082431 Check |pmc= value (help). PMID 31925639.Wang, Huiwen; Qiu, Jiadi; Liu, Haoquan; Xu, Ying; Jia, Ya; Zhao, Yunjie (December 2019). "HKPocket: human kinase pocket database for drug design". BMC Bioinformatics. 20 (1): 617. doi:10.1186/s12859-019-3254-y. PMC 6884818 Check |pmc= value (help). PMID 31783725.Jacoby, Edgar; Tresadern, Gary; Bembenek, Scott; Wroblowski, Berthold; Buyck, Christophe; Neefs, Jean-Marc; Rassokhin, Dmitrii; Poncelet, Alain; Hunt, Jeremy; van Vlijmen, Herman (June 2015). "Extending kinome coverage by analysis of kinase inhibitor broad profiling data". Drug Discovery Today. 20 (6): 652–658. doi:10.1016/j.drudis.2015.01.002. PMID 25596550.
  6. Hambly, Kevin; Danzer, Joseph; Muskal, Steven; Debe, Derek A. (1 August 2006). "Interrogating the druggable genome with structural informatics". Molecular Diversity. 10 (3): 273–281. doi:10.1007/s11030-006-9035-3. PMID 17031532.
  7. Palmer, Brian; Danzer, Joseph F.; Hambly, Kevin; Debe, Derek A. (1 July 2006). "StructSorter: A Method for Continuously Updating a Comprehensive Protein Structure Alignment Database". Journal of Chemical Information and Modeling. 46 (4): 1871–1876. doi:10.1021/ci0601012. PMID 16859318.
  8. Jacoby, Edgar (11 May 2006). Chemogenomics: Knowledge-based Approaches To Drug Discovery. World Scientific. ISBN 978-1-78326-009-6. Search this book on
  9. "Eidogen And Sertanty Inc. Complete Merger To Become Eidogen-Sertanty, Inc". BioSpace. 20 October 2005."Drug Discovery Software | Eidogen-Sertanty". eidogen-sertanty.com.

External links[edit]


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