Emily Sylwestrak
Emily Sylwestrak is a neuroscientist and assistant professor of Biology, Institute of Neuroscience, at the University of Oregon. Her lab aims to understand how different neuronal populations work together to drive behavior, with specific interest in how the Habenula is involved in behavior.
Education & Research
Dr. Sylwestrak earned her bachelor's degree in biology in 2006 from the University of Illinois at Urbana–Champaign, where she examined the electrophysiological properties of thalamic neurons in the lab of Dr. Lee Cox. She then went on to earn her Ph.D. in neuroscience from the University of California, San Diego in 2011 in the lab of Dr. Anirvan Ghosh. During her Ph.D. she studied the role of a class of cell surface molecules, leucine-rich repeat containing proteins, which are involved in controlling synapse formation within the hippocampus. Her work with Dr. Ghosh identified that the LRR protein Elfn1 is critical in establishing target-cell specificity in the hippocampus[1] Sylwestrak continued studying molecular control of synapse function at F. Hoffmann-La Roche with Dr. Ghosh and Dr. Peter Scheiffele. In 2014, she started her postdoc in the lab of Karl Deisseroth at Stanford University. During her postdoc she developed protocols for labeling RNA in intact, transparent tissues merging molecular information with 3-D structural information [2][3]. She started her lab at the University of Oregon in Spring of 2019. Her lab focuses on how different habenular cell types encode aspects of motivated behavior; this work suggests that dysfunction within the habenula may contribute to altered reward process in neuropsychiatric disorders[4][5][6].
Awards & Honors
- Next Generation Leaders Allen Institute for Brain Science 2018[7]
- NARSAD Young Investigator Brain & Behavior Research Foundation 2018 [8]
References
- ↑ Stachniak, Tevye Jason; Sylwestrak, Emily Lauren; Scheiffele, Peter; Hall, Benjamin J.; Ghosh, Anirvan (2019-06-05). "Elfn1-Induced Constitutive Activation of mGluR7 Determines Frequency-Dependent Recruitment of Somatostatin Interneurons". The Journal of Neuroscience: The Official Journal of the Society for Neuroscience. 39 (23): 4461–4474. doi:10.1523/JNEUROSCI.2276-18.2019. ISSN 1529-2401. PMC 6554623 Check
|pmc=value (help). PMID 30940718. - ↑ Wang, Xiao; Allen, William E.; Wright, Matthew A.; Sylwestrak, Emily L.; Samusik, Nikolay; Vesuna, Sam; Evans, Kathryn; Liu, Cindy; Ramakrishnan, Charu; Liu, Jia; Nolan, Garry P. (07 27, 2018). "Three-dimensional intact-tissue sequencing of single-cell transcriptional states". Science. 361 (6400): eaat5691. doi:10.1126/science.aat5691. ISSN 1095-9203. PMC 6339868. PMID 29930089. Check date values in:
|date=(help) - ↑ Sylwestrak, Emily Lauren; Rajasethupathy, Priyamvada; Wright, Matthew Arnot; Jaffe, Anna; Deisseroth, Karl (2016-02-11). "Multiplexed Intact-Tissue Transcriptional Analysis at Cellular Resolution". Cell. 164 (4): 792–804. doi:10.1016/j.cell.2016.01.038. ISSN 1097-4172. PMC 4775740. PMID 26871636.
- ↑ "Sylwestrak Lab". Sylwestrak Lab. Retrieved 2020-03-07.
- ↑ "Emily Sylwestrak | Institute of Neuroscience". ion.uoregon.edu. Retrieved 2020-03-07.
- ↑ Emily Sylwestrak | Showcase 2018, retrieved 2020-03-07
- ↑ "Allen Institute Announces 2018 Next Generation Leaders". Allen Institute. 2018-11-02. Retrieved 2020-03-07.
- ↑ "Dr. Emily Sylwestrak awarded Young Investigator NARSAD award | Womxn in Neuroscience". blogs.uoregon.edu. Retrieved 2020-03-07.
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