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Eradicability

From EverybodyWiki Bios & Wiki


Eradicability is a trait that some species have and some do not.[1] Eradicability is also known as feasibility of eradication, practicality of eradication and probability of successful eradication.[2][3] Having eradicability means a species could be made extinct.[1] Anyone trying to eradicate an infectious disease cares about eradicability.[1]

It is difficult to find out what the eradicability of a disease is.[4] To do that we need to know: How easy is eradication?; Do other people support eradication?[4][5]

Things which will affect eradicability

Things that make a thing less eradicable include:

  • Long dispersal distance. (A thing has lower eradicability if its offspring travel long distances.)[6]
  • Broad host range. (A thing has lower eradicability if it is a parasite which can feed from many different kinds of things.)[6]
  • If it is a disease, multiple pathogens causing the disease. (A disease has lower eradicability if it is caused by more than one species.)[7]
  • Local elimination has not yet been achieved. (A disease has lower eradicability if it has not even been killed in a smaller area yet.)[7]
  • Perception that the species isn't a big problem. (A thing has lower eradicability if people do not support eradication because they think it is not a real problem.)[7]
  • Lack of financial support. (A thing has lower eradicability if large amounts of money are not being given to the eradication effort.)[7]
  • Lack of political support. (A thing has lower eradicability if politicians do not support eradication.)[7]
  • High estimated cost of eradication. (A thing has lower eradicability if experts find that eradication will cost a lot.)[7]
  • Political instability in the affected countries. (A thing has lower eradicability if the area's governments are not working well.)[7]
  • Lack of identifiable symptoms. (A disease has lower eradicability if you cannot see from the outside whether someone has it.)[7]
  • Large geographic range. (A thing has lower eradicability if it lives in a large number of places.)[3]
  • Specifically for filarial diseases: Things that make filarial diseases less eradicable include:
  • Higher annual biting rate of the vector. (A filarial disease has lower eradicability if the mosquitoes that carry it bite more often.)[8]
  • Higher annual transmission potential of the host. (A filarial disease has lower eradicability if the humans that might get it are getting it from mosquitoes more often.)[8]
  • Facilitative effects in the parasite. (A filarial disease has lower eradicability if each parasite helps others of its own species.)[8]
  • Lack of density-dependent reproductive decline. (A filarial disease has lower eradicability if it doesn't stop having offspring when its area becomes crowded.)[8]
  • Low threshold biting rate. (A filarial disease has lower eradicability if it can still infect new victims even if mosquitoes are not biting very much.)[8]
  • Low transmission thresholds in general. (A filarial disease has lower eradicability if it never stops infecting new victims for any reason.)[8]

Vaccination makes some diseases more eradicable.[9] Several scientific studies find eradicability isn't sufficient with only voluntary vaccination, however.[10] Those studies include Bauch & Earn 2004, Chen 2006 and Perisic & Bauch 2009.[10]

Eradicability of specific species

A disease with high eradicability is lymphatic filariasis.[1]

Experts believe COVID-19 has a higher eradicability than polio.[11] Experts believe COVID-19 has a much lower eradicability than smallpox.[11]

Experts think P. striiformis is not eradicable because it has a long potential dispersal distance and a broad host range.[6]

Experts think X. fastidiosa in Europe is not eradicable.[12]

Organizations

The Carter Center International Task Force for Disease Eradication (ITFDE) studies diseases' eradicability.[13] ITFDE has opinions about diseases' eradicability.[14] These opinions come from these studies.[14] ITFDE publishes these opinions in reports.[14] ITFDE has opinions about the eradicability of: Measles morbillivirus, Treponema pallidum subsp. pertenue, Schistosoma mansoni, Onchocerca volvulus, Onchocerca ochengi, Leishmania infantum (syn. L. chagasi), L. donovani and other diseases.[14]

Economics

Questions about who will pay for disease eradications are very important to the probability of eradication – eradicability.[15]

References

  1. 1.0 1.1 1.2 1.3 2023. Issue 9. Volume 16. REVIEW ARTICLE. Sinha, Aashna; Kumar, Sudhashekhar; Dayal, Deen; Yadav, Vaishali; Pramanik, Atreyi; Chaubey, Kundan Kumar; Kumar, Sanjay. Pages 385-399. api.semanticscholar.org/CorpusID:260638260. doi.org/10.4103/1995-7645.380729. Elimination of lymphatic filariasis: Where do we stand so far?
  2. 2012. dx.doi.org/10.1603/EC11293. Combining Tactics To Exploit Allee Effects For Eradication Of Alien Insect Populations.
  3. 3.0 3.1 2014. Volume 16. Pages 401–414. Patrick C. Tobin, John M. Kean, David Maxwell Suckling, Deborah G. McCullough, Daniel A. Herms & Lloyd D. Stringer. doi.org/10.1007/s10530-013-0529-5. Determinants of successful arthropod eradication programs.
  4. 4.0 4.1 Issue 1. 2013. Pages 54–63. Donald R. Hopkins. Volume 368. api.semanticscholar.org/CorpusID:205116347. www.ncbi.nlm.nih.gov/pubmed/23281976. doi.org/10.1056/nejmra1200391. Disease Eradication.
  5. pubmed.ncbi.nlm.nih.gov/11029980. www.ncbi.nlm.nih.gov/pmc/articles/PMC1446384/. doi.org/10.2105/ajph.90.10.1515.
  6. 6.0 6.1 6.2 2020. link.springer.com/article/10.1007/s12571-020-01016-z.
  7. 7.0 7.1 7.2 7.3 7.4 7.5 7.6 7.7 2024. By Max Roser, Sophie Ochmann, Hannah Behrens, Hannah Ritchie and Bernadeta Dadonaite. ourworldindata.org/eradication-of-diseases. Eradication of Diseases : Which ones could we eradicate in our lifetimes and how?
  8. 8.0 8.1 8.2 8.3 8.4 8.5 2005. Issue 2. Volume 21. Hans-Peter Duerr, Klaus Dietz, Martin Eichner. doi.org/10.1016/j.pt.2004.11.011. Determinants of the eradicability of filarial infections: a conceptual approach.
  9. 2016. www.sciencedirect.com/science/article/pii/S1571064516300756
  10. 10.0 10.1 2010. Volume 7. royalsocietypublishing.org/doi/10.1098/rsif.2010.0142.
  11. 11.0 11.1
    This is for most people.
    Script error: The function "in_lang" does not exist.. open access 2021. doi.org/10.1136/bmjgh-2021-006810. Commentary: Global eradication of COVID-19 probably feasible, and more so than for polio, say public health experts.
    This is for experts.
    Script error: The function "in_lang" does not exist.. open access 2021. Commentary. Nick Wilson, Osman D Mansoor, Matthew J Boyd orcid.org/0000-0002-1387-5047, Amanda Kvalsvig, Michael G Baker. doi.org/10.1136/bmjgh-2021-006810. We should not dismiss the possibility of eradicating COVID-19: comparisons with smallpox and polio.
  12. 2019. apsjournals.apsnet.org/doi/10.1094/phyto-08-18-0319-fi.
  13. 2023. www.cartercenter.org/health/itfde/history.html. History of the International Task Force For Disease Eradication.
  14. 14.0 14.1 14.2 14.3 2023. www.cartercenter.org/news/publications/health/itfde_reports.html. International Task Force for Disease Eradication – Program Reports.
  15. 2013. Page 20120149. Scott Barrett. api.semanticscholar.org/CorpusID:5801373. dx.doi.org/10.1098/rstb.2012.0149. Economic considerations for the eradication endgame.

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