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Eradicability

From EverybodyWiki Bios & Wiki


Eradicability is a trait that some species have and some do not.[1] Eradicability is also known as feasibility of eradication, practicality of eradication and probability of successful eradication.[2][3] Having eradicability means a species could be made extinct.[1] Anyone trying to eradicate an infectious disease cares about eradicability.[1]

It is difficult to find out what the eradicability of a disease is.[4] To do that we need to know: How easy is eradication?; Do other people support eradication?[4][5]

Things which will affect eradicability

Things that make a thing less eradicable include:

  • Long dispersal distance. (A thing has lower eradicability if its offspring travel long distances.)[6]
  • Broad host range. (A thing has lower eradicability if it is a parasite which can feed from many different kinds of things.)[6]
  • If it is a disease, multiple pathogens causing the disease. (A disease has lower eradicability if it is caused by more than one species.)[7]
  • Local elimination has not yet been achieved. (A disease has lower eradicability if it has not even been killed in a smaller area yet.)[7]
  • Perception that the species isn't a big problem. (A thing has lower eradicability if people do not support eradication because they think it is not a real problem.)[7]
  • Lack of financial support. (A thing has lower eradicability if large amounts of money are not being given to the eradication effort.)[7]
  • Lack of political support. (A thing has lower eradicability if politicians do not support eradication.)[7]
  • High estimated cost of eradication. (A thing has lower eradicability if experts find that eradication will cost a lot.)[7]
  • Political instability in the affected countries. (A thing has lower eradicability if the area's governments are not working well.)[7]
  • Lack of identifiable symptoms. (A disease has lower eradicability if you cannot see from the outside whether someone has it.)[7]
  • Large geographic range. (A thing has lower eradicability if it lives in a large number of places.)[3]
  • Specifically for filarial diseases: Things that make filarial diseases less eradicable include:
  • Higher annual biting rate of the vector. (A filarial disease has lower eradicability if the mosquitoes that carry it bite more often.)[8]
  • Higher annual transmission potential of the host. (A filarial disease has lower eradicability if the humans that might get it are getting it from mosquitoes more often.)[8]
  • Facilitative effects in the parasite. (A filarial disease has lower eradicability if each parasite helps others of its own species.)[8]
  • Lack of density-dependent reproductive decline. (A filarial disease has lower eradicability if it doesn't stop having offspring when its area becomes crowded.)[8]
  • Low threshold biting rate. (A filarial disease has lower eradicability if it can still infect new victims even if mosquitoes are not biting very much.)[8]
  • Low transmission thresholds in general. (A filarial disease has lower eradicability if it never stops infecting new victims for any reason.)[8]

Vaccination makes some diseases more eradicable.[9] Several scientific studies find eradicability isn't sufficient with only voluntary vaccination, however.[10] Those studies include Bauch & Earn 2004, Chen 2006 and Perisic & Bauch 2009.[10]

Eradicability of specific species

A disease with high eradicability is lymphatic filariasis.[1]

Experts believe COVID-19 has a higher eradicability than polio.[11] Experts believe COVID-19 has a much lower eradicability than smallpox.[11]

Experts think P. striiformis is not eradicable because it has a long potential dispersal distance and a broad host range.[6]

Experts think X. fastidiosa in Europe is not eradicable.[12]

Organizations

The Carter Center International Task Force for Disease Eradication (ITFDE) studies diseases' eradicability.[13] ITFDE has opinions about diseases' eradicability.[14] These opinions come from these studies.[14] ITFDE publishes these opinions in reports.[14] ITFDE has opinions about the eradicability of: Measles morbillivirus, Treponema pallidum subsp. pertenue, Schistosoma mansoni, Onchocerca volvulus, Onchocerca ochengi, Leishmania infantum (syn. L. chagasi), L. donovani and other diseases.[14]

Economics

Questions about who will pay for disease eradications are very important to the probability of eradication – eradicability.[15]

References

  1. ↑ 1.0 1.1 1.2 1.3 2023. Issue 9. Volume 16. REVIEW ARTICLE. Sinha, Aashna; Kumar, Sudhashekhar; Dayal, Deen; Yadav, Vaishali; Pramanik, Atreyi; Chaubey, Kundan Kumar; Kumar, Sanjay. Pages 385-399. api.semanticscholar.org/CorpusID:260638260. doi.org/10.4103/1995-7645.380729. Elimination of lymphatic filariasis: Where do we stand so far?
  2. ↑ 2012. dx.doi.org/10.1603/EC11293. Combining Tactics To Exploit Allee Effects For Eradication Of Alien Insect Populations.
  3. ↑ 3.0 3.1 2014. Volume 16. Pages 401–414. Patrick C. Tobin, John M. Kean, David Maxwell Suckling, Deborah G. McCullough, Daniel A. Herms & Lloyd D. Stringer. doi.org/10.1007/s10530-013-0529-5. Determinants of successful arthropod eradication programs.
  4. ↑ 4.0 4.1 Issue 1. 2013. Pages 54–63. Donald R. Hopkins. Volume 368. api.semanticscholar.org/CorpusID:205116347. www.ncbi.nlm.nih.gov/pubmed/23281976. doi.org/10.1056/nejmra1200391. Disease Eradication.
  5. ↑ pubmed.ncbi.nlm.nih.gov/11029980. www.ncbi.nlm.nih.gov/pmc/articles/PMC1446384/. doi.org/10.2105/ajph.90.10.1515.
  6. ↑ 6.0 6.1 6.2 2020. link.springer.com/article/10.1007/s12571-020-01016-z.
  7. ↑ 7.0 7.1 7.2 7.3 7.4 7.5 7.6 7.7 2024. By Max Roser, Sophie Ochmann, Hannah Behrens, Hannah Ritchie and Bernadeta Dadonaite. ourworldindata.org/eradication-of-diseases. Eradication of Diseases : Which ones could we eradicate in our lifetimes and how?
  8. ↑ 8.0 8.1 8.2 8.3 8.4 8.5 2005. Issue 2. Volume 21. Hans-Peter Duerr, Klaus Dietz, Martin Eichner. doi.org/10.1016/j.pt.2004.11.011. Determinants of the eradicability of filarial infections: a conceptual approach.
  9. ↑ 2016. www.sciencedirect.com/science/article/pii/S1571064516300756
  10. ↑ 10.0 10.1 2010. Volume 7. royalsocietypublishing.org/doi/10.1098/rsif.2010.0142.
  11. ↑ 11.0 11.1
    This is for most people.
    Script error: The function "in_lang" does not exist.. open access 2021. doi.org/10.1136/bmjgh-2021-006810. Commentary: Global eradication of COVID-19 probably feasible, and more so than for polio, say public health experts.
    This is for experts.
    Script error: The function "in_lang" does not exist.. open access 2021. Commentary. Nick Wilson, Osman D Mansoor, Matthew J Boyd orcid.org/0000-0002-1387-5047, Amanda Kvalsvig, Michael G Baker. doi.org/10.1136/bmjgh-2021-006810. We should not dismiss the possibility of eradicating COVID-19: comparisons with smallpox and polio.
  12. ↑ 2019. apsjournals.apsnet.org/doi/10.1094/phyto-08-18-0319-fi.
  13. ↑ 2023. www.cartercenter.org/health/itfde/history.html. History of the International Task Force For Disease Eradication.
  14. ↑ 14.0 14.1 14.2 14.3 2023. www.cartercenter.org/news/publications/health/itfde_reports.html. International Task Force for Disease Eradication – Program Reports.
  15. ↑ 2013. Page 20120149. Scott Barrett. api.semanticscholar.org/CorpusID:5801373. dx.doi.org/10.1098/rstb.2012.0149. Economic considerations for the eradication endgame.

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