Glucose-responsive insulin
Glucose-responsive insulin patch (also known as smart insulin, adaptive insulin, smart insulin patch, MK-2640-001 or Sensulin, is an experimental type of insulin delivery patch which is hoped will keep blood sugars in the normal range in diabetics. The patch is supposed to adapt by releasing either less or more insulin relative to the level of glucose in the bloodstream.[1][2][3] Results of an animal model were published in 2015.[4]
Research[edit]
Merck[edit]
Merck started a study in November 2014. The study was completed in July 2016, but no results have been posted.[5]
References[edit]
- ↑ Mohammadi D (10 November 2017). "Towards a smarter insulin". The Pharmaceutical Journal.
- ↑ "New Smart Insulin Patch Could Be a 'Game Changer'". IFL Science. Retrieved 15 June 2018.
- ↑ http://www.iflscience.com/health-and-medicine/new-smart-insulin-patch-could-be-game-changer/
- ↑ Yu J, Zhang Y, Ye Y, DiSanto R, Sun W, Ranson D, Ligler FS, Buse JB, Gu Z (July 2015). "Microneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery". Proceedings of the National Academy of Sciences of the United States of America. 112 (27): 8260–5. doi:10.1073/pnas.1505405112. PMC 4500284. PMID 26100900.
- ↑ "A Three-part Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of MK-2640 in Healthy Participants (Part I) and Participants With Type 1 Diabetes Mellitus (Parts II and III) (MK-2640-001) - Full Text View - ClinicalTrials.gov". clinicaltrials.gov. Retrieved 2017-03-03.
External links[edit]
- Sensulin, a pharmaceutical company researching a type of glucose-responsive insulin
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