Groove synthesis
From EverybodyWiki Bios & Wiki
The groove synthesis is the synthesis of alkyl halide from alcohols via treatment at high temperatures with hydrogen halide in the presence of anhydrous zinc chloride as a catalyst. Concentrated HCl + anhydrous ZnCl2 is known as Lucas reagent.
R–OH + HX ————ZnCl2————> R-X + H2O 300°C
Reactivity order: HI > HBr > HCl > HF 3° > 2° > 1° > MeOH.
2° and 3° alcohols undergo SN1; 1° and MeOH undergo SN2 mechanism.
 | This article has not been added to any categories. Please help out by adding categories to it so that it can be listed with similar articles, in addition to a stub category. Please remove this tag after categorizing. (February 2015) |
This article "Groove synthesis" is from Wikipedia. The list of its authors can be seen in its historical. Articles copied from Draft Namespace on Wikipedia could be seen on the Draft Namespace of Wikipedia and not main one.
