James Kronstad
| James Kronstad | |
|---|---|
 James-kronstad-25th.jpg | |
| Born | James Warren Kronstad |
| Other names | Jim Kronstad |
| 🎓 Alma mater | Oregon State University, University of Washington |
| 💼 Occupation | |
| 🏅 Awards | Burroughs Wellcome Fund Scholar in Molecular Pathogenic Mycology (1999-2004)
Fellow, American Academy of Microbiology, American Society for Microbiology, elected 2005 Fellow, American Association for the Advancement of Science, elected 2006 Fellow, Canadian Institute for Advanced Research (Fungal Kingdom: Threats & Opportunities), appointed 2019 Power Corporation Fellow of the Canadian Institute for Advanced Research program: Fungal Kingdom: Threats & Opportunities (2023-2028) |
| 🌐 Website | https://kronstadlab.msl.ubc.ca |
James Kronstad
James Warren Kronstad (born March 8, 1957) is a microbiologist at the University of British Columbia.[1]. He is a Professor in the Michael Smith Laboratories and the Dept. of Microbiology & Immunology, and he served as Director of the Michael Smith Laboratories from 2008 to 2017 [2][3]. Dr. Kronstad is a Burroughs Wellcome Fund Scholar in Molecular Pathogenic mycology [4][5], the Power Corporation Fellow of the CIFAR program: Fungal Kingdom, Threats & Opportunities [4], and a fellow of the American Academy of Microbiology [4] and the American Association for the Advancement of Science [4]
Education
Kronstad received his Bachelor of Science degree from Oregon State University (1979), followed by his M.Sc. (1982) and Ph.D. (1984) degrees from the University of Washington.[4]
Career and Research
Dr. Kronstad was recruited to the University of British Columbia by the Nobel laureate Dr. Michael Smith 8 in 1989, after completing postdoctoral positions at ZymoGenetics, Inc. (Seattle, WA, U.S.A.) (Wiki), and the University of Wisconsin–Madison (Madison, Wi, U.S.A). His postdoctoral work focused on fungal mating systems including characterization of the pheromone response in Saccharomyces cerevisiae.[6], and cloning the b mating locus of Ustilago maydis [7]. Kronstad’s current research program focuses on understanding mechanisms of nutrient sensing and acquisition that support the pathogenesis of fungi that cause diseases on plants or animals [8]. One theme of his research investigates the impact that pathogenic fungi have on food security by threatening the production of cereal crops. For example, the Kronstad group discovered that exposure of the plant pathogen Ustilago maydis to combinations of carbon sources in culture triggered the expression of phenotypes normally observed only during biotrophic development in host plants [9]. A second theme of Kronstad’s research focuses on fungi such as Cryptococcus neoformans that cause meningitis in immunocompromised people (e.g., HIV/AIDS patients). A long-term effort has revealed the regulatory and acquisition functions that enable fungi to compete for iron during proliferation in animal host [10]. Other studies have characterized the impact of glutathione on the virulence of C. neoformans to highlight the importance of redox homeostasis and metabolic compensation in adaptation to the mammalian host environment [11]. The core funding for Kronstad’s research comes from the Natural Sciences and Engineering Research Council (https://www.nserc-crsng.gc.ca/), the Canadian Institutes of Health Research (https://www.cihr-irsc.gc.ca/e/193.html), and the National Institute of Allergy and Infectious Diseases (https://www.niaid.nih.gov/) [4]
Awards and Honors
Burroughs Wellcome Fund Scholar in Molecular Pathogenic Mycology (1999-2004).[5]
Fellow, American Academy of Microbiology, American Society for Microbiology, elected 2005 [4]
Fellow, American Association for the Advancement of Science, elected 2006.[4]
Fellow, Canadian Institute for Advanced Research (Fungal Kingdom: Threats & Opportunities),
appointed 2019.[4]
Power Corporation Fellow of the Canadian Institute for Advanced Research program: Fungal
Kingdom: Threats & Opportunities (2023-2028).[4]
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- ↑ "James Kronstad". scholar.google.ca. Retrieved 2025-07-02.
- ↑ "Jim Kronstad". www.msl.ubc.ca. Retrieved 2025-07-02.
- ↑ "Jim Kronstad | MBIM". mbim.ubc.ca. Retrieved 2025-07-02.
- ↑ 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 "James Kronstad". CIFAR. Retrieved 2025-07-02.
- ↑ 5.0 5.1 https://www.bwfund.org/wp-content/uploads/2020/11/2001-Annual-Report.pdf
- ↑ Kronstad, J W; Leong, S A (February 1989). "Isolation of two alleles of the b locus of Ustilago maydis". Proceedings of the National Academy of Sciences. 86 (3): 978–982. Bibcode:1989PNAS...86..978K. doi:10.1073/pnas.86.3.978. PMC 286602. PMID 2915990.
- ↑ "Overview | Kronstad Lab". kronstadlab.msl.ubc.ca. Retrieved 2025-07-24.
- ↑ Kretschmer, Matthias; Damoo, Djihane; Sun, Sherry; Lee, Christopher W. J.; Croll, Daniel; Brumer, Harry; Kronstad, James (2022-06-10). "Organic acids and glucose prime late-stage fungal biotrophy in maize". Science. 376 (6598): 1187–1191. Bibcode:2022Sci...376.1187K. doi:10.1126/science.abo2401. ISSN 0036-8075.
- ↑ Caza, Mélissa; Kronstad, James W. (2013). "Shared and distinct mechanisms of iron acquisition by bacterial and fungal pathogens of humans". Frontiers in Cellular and Infection Microbiology. 3: 80. doi:10.3389/fcimb.2013.00080. ISSN 2235-2988. PMC 3832793. PMID 24312900.
- ↑ Black, Braydon; da Silva, Leandro Buffoni Roque; Hu, Guanggan; Qu, Xianya; Smith, Daniel F. Q.; Magaña, Armando Alcázar; Horianopoulos, Linda C.; Caza, Mélissa; Attarian, Rodgoun; Foster, Leonard J.; Casadevall, Arturo; Kronstad, James W. (2024-07-02). "Glutathione-mediated redox regulation in Cryptococcus neoformans impacts virulence". Nature Microbiology. 9 (8): 2084–2098. doi:10.1038/s41564-024-01721-x. ISSN 2058-5276. PMC 11930340 Check
|pmc=value (help). PMID 38956248 Check|pmid=value (help). - ↑ Black, Braydon; da Silva, Leandro Buffoni Roque; Hu, Guanggan; Qu, Xianya; Smith, Daniel F. Q.; Magaña, Armando Alcázar; Horianopoulos, Linda C.; Caza, Mélissa; Attarian, Rodgoun; Foster, Leonard J.; Casadevall, Arturo; Kronstad, James W. (2024-07-02). "Glutathione-mediated redox regulation in Cryptococcus neoformans impacts virulence". Nature Microbiology. 9 (8): 2084–2098. doi:10.1038/s41564-024-01721-x. ISSN 2058-5276. PMC 11930340 Check
|pmc=value (help). PMID 38956248 Check|pmid=value (help).
