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Jerry Sebag

From EverybodyWiki Bios & Wiki





J. Sebag, MD, FACS, FRCOphth, FARVO is an American ophthalmologist, originally born in Tiberias, Israel, coming to the United States of America at the age of 3[1]. In 1986, Dr. Sebag founded the VMR Institute for Vitreous Macula Retina, aiming to provide state-of-the-art diagnostics and therapeutics of the eye with precision, compassion, and care. Dr. Sebag specialises in evaluating and treating a variety of eye conditions employing laser therapies, injections, and surgery...[2]. Additionally, he is a vocal proponent of pushing for better understanding, diagnosis, and treatment of vision degrading myodesopsia (eye floaters)[3][4].

Dr. Sebag is considered among ophthalmologists a world leading authority on vitreous, the gel which fills the centre of the eye, having authored three books, as well as many original peer-reviewed articles, chapters, and editorials on diseases, drug therapy, and surgery of the Vitreous, Macula, and Retina (VMR). In 2018 Dr. Sebag founded the VMR Research Foundation to support and promote research and development of improved diagnostics and therapeutics for disorders of the eye, primarily vitreo-retinal diseases[5].

Education

After graduating from the Bronx High School of Science, New York in 1969, Dr. Sebag received a B.A. degree in Biological Sciences from Columbia College in New York (1969-1973). During 1973-75 Dr. Sebag conducted research on the application of computers to medical decision-making at the Karolinska in Stockholm, Sweden. In 1978 this work received First Prize in a national competition on Preventive Medicine organized by the American Health Foundation. Sebag attended medical school at the College of Physicians & Surgeons, Columbia University in New York where he obtained his M.D. in 1979. At Columbia, he began vitreous research which in 1979 was awarded the Doctor Alfred P. Steiner Research Award, the Titus Munson Coan Prize for Excellence in Research, and the Edith & Denton McKane Award for Outstanding Research in Ophthalmology. Dr. Sebag then completed an internship at Cedar-Sinai Medical Center / UCLA in Los Angeles (1979-1980), and did his ophthalmology residency at Harvard Medical School in Boston, Massachusetts (1980-1983), during which time he continued independent vitreous research. He then completed a vitreo-retinal fellowship with the Schepens Retina Associates & Eye Research Institute of Retina Foundation at Harvard Medical School.[2]

Research and Career

Dr. Sebag has spent the majority of his career focusing on advancing knowledge and understanding of vitreous, the clear gel that fills the center of the eye between the lens and the retina of humans and other vertebrates. He has authored over 200 publications and his Google Scholar H-index is 49 (January 2021). Dr Sebag’s publications are available on ResearchGate (https://www.researchgate.net/profile/Jerry_Sebag).

His research outputs include a ground-breaking monograph on the vitreous body in 1989, entitled ‘The Vitreous: Structure, Function, and Pathobiology’[6] which married basic and clinical sciences highlighting the importance of vitreous. Since then, Dr. Sebag has worked towards significantly advancing the study of the vitreous body. The latest book ‘Vitreous - in Health and Disease’[7], which contains 925 pages written by 90 co-authors and edited by Dr. Sebag, addresses current scientific knowledge as well as clinical perspectives gleaned from a quarter century of study since the 1989 edition. Included are discussions on vitreous biochemistry, anatomy, physiology, pathology, surgery, and pharmacotherapy. Most recently, Dr. Sebag has published a comprehensive review on eye floaters in the journal Progress in Retinal and Eye Research, entitled ‘Vitreous and Vision Degrading Myodesopsia’[8]

Dr. Sebag has pioneered the use of ultrasonography to evaluate vitreous structure and measuring contrast-sensitivity function to diagnose clinically significant cases of vision degrading myodesopsia[9]. He also promoted the use of ‘limited vitrectomy’ to cure it, a 10 minute procedure that minimises risks while achieving significant elimination of vitreous floaters[10]. In contrast to other treatment modalities, this approach has been validated in a number of studies performed at several centers throughout the world. This work has led to objective, quantitative evidence of safety and efficacy in the use of limited vitrectomy to cure vision degrading Myodesopsia[11]

Research Appointments

Dr. Sebag has held many research appointments over his career, which are listed below[12].

Dr. Sebag's Research Appointments
Year Role Institute Location
1972 Columbia College Research Fellowship Columbia University Columbia, New York
1973 Research Associate, Department of Pathology College of Physicians & Surgeons,

Columbia University

Columbia, New York
1973-75 Thord-Gray Research Fellow of the American-Scandinavian Foundation Karolinska Institute Stockholm, Sweden
1976 Immunology Research Fellow University of New Mexico School of Medicine Albuquerque, New Mexico
1978-79 Research Associate Edward S. Harkness Eye Research Institute, College of Physicians & Surgeons, Columbia University Columbia, New York
1982-83 Research Associate Eye Research Institute of Retina Foundation Boston, Massachusetts
1983-84 Guggenheim Fellow The John Simon Guggenheim Memorial Foundation, National Institute of Health & Medical Research (I.N.S.E.R.M.) Paris, France
1987-90 Adjunct Clinical Assistant Scientist Eye Research Institute of Retina Foundation, Harvard Medical School Boston, Massachusetts
1990-92 Assistant Clinical Professor of Ophthalmology Doheny Eye Institute, University of Southern California Los Angeles, USA
1992-2003 Associate Clinical Professor of Ophthalmology Doheny Eye Institute, University of Southern California Los Angeles, USA
2003-2014 Professor of Clinical Ophthalmology Doheny Eye Institute, University of Southern California Los Angeles, USA
2018 Senior Research Scientist Doheny Eye Institute, University of California Los Angeles Los Angeles, USA
2019 Professor of Clinical Ophthalmology Geffen School of Medicine, University of California Los Angeles Los Angeles, USA

Professional Societies

Professional Activities

Dr Sebag's Professional Activities
Year Role Organisation
1991-92 Chairman, Professional Education American Diabetes Association
1993-95 President American Diabetes Association
1993 Annual Meeting Co-Chair Western Retina Study Club
1995-97 Member, Board of Directors American Diabetes Association
1995-99 National Advisory Board Schepens International Society
1995 Organizing Committee (annual meetings) SPIE Optical Engineering Society
2000 Board of Directors Schepens International Society
2005 Editorial Board Member Graefe’s Archive for Clinical and Experimental Ophthalmology
2012-16 Program Committee, Chairman (2016) American Ophthalmological Society

Outreach and Public Engagement

Dr Sebag has been actively involved in engaging with sufferers of vision degrading myodesopsia (eye floaters), and has appeared on the Eye Floaters Action Movement podcast [1] and the Straight From the Cutter's Mouth podcast [2]. His work on getting severe eye floaters recognised as a disease (vision degrading myodesopsia) has been covered in an issue of the Euro Times magazine in an article entitled "Vitrectomy for Myodesopsia, Vitreous floaters - from nuisance to disease"[14]. As of 2019, Dr Sebag is also working directly with the VDM Project, a non-profit organisation aiming to unite sufferers of vision degrading myodesopsia, and crowdfund research into alternative treatment options[15]. The issue of myodesopsia and Dr Sebag's work with the VDM Project was covered in a 2021 article in Italian magazine Terra Nuova[16]. In 2020, he was interview by the Review of Ophthalmology magazine, discussing his approach to treating vitreous floaters, along with a number of other ophthalmologists[4].

Dr Sebag has spoken as a keynote lecturer at the European Society of Ophthalmology's annual international conferences in 2017 and 2019, which were filmed and published by Touch Medical Media Services on Youtube.

In 2011, Dr Sebag was interviewed by JLife magazine (a.k.a. Orange County Jewish Life) about the story of his early life, emigrating to the U.S.A, and having originally attended a yeshiva before pursuing a scientific career[1]

In 2014, he was noted to have made donations of up $50,000 towards the improvement of footpaths and trails in his local community, at the Top of the World Drive and sidewalk in Laguna Beach, California, as reported on by the Laguna Beach Independent[17]

Awards and Honours

Professional Certifications

Affiliations

Dr. Sebag’s current academic affiliations are with the Doheny Eye Institute, where he was the first appointed Senior Research Scientist; and the Geffen School of Medicine, University of California Los Angeles, where he is a full professor of Clinical Ophthalmology.

Dr. Sebag previously had research collaborations with INSERM (Dr. Yves Courtois, Paris), The Joslin Diabetes Center, Harvard Medical School (Dr. Lloyd Paul Aiello), The University of Sydney (Dr. Michelle Madigan, Australia), and NASA (Dr. Rafat Ansari, Cleveland, Ohio).

Dr. Sebag currently maintains active research collaborations with Dr. Ron Silverman at the Columbia College of Physicians & Surgeons (New York), Dr. Jonathan Mamou and Dr. Jeff Ketterling of Riverside Research (New York), Dr. Felix Sauvage and Professor Stefaan deSmedt at the School of Pharmaceutical Sciences at the University of Ghent (Belgium), Dr. Ireneusz Grulkowski at the Copernicus University (Poland), Professor Pablo Artal at The University of Murcia (Spain), and Dr. Paolo Stanga at the Institute of Ophthalmology (London).

Personal Life

Dr Sebag has interests in music, boating, and ballroom dancing with his wife, whom he watches compete at local pro-am events. Dr. Sebag also loves to travel, in particular Europe, having lived in Stockholm, Sweden (1973-75) and Paris, France (1983-84).  As a result, he is fluent in Swedish and French.[2]

References

  1. ↑ 1.0 1.1 OC, JLife (31 October 2011). "Saving Sight". JLife (Orange County Jewish Life). Retrieved 2 February 2021. Unknown parameter |url-status= ignored (help)
  2. ↑ 2.0 2.1 2.2 "Retinal Specialist | Board certified ophthalmologist | 92647". Retina Specialists Huntington Beach 92647. Retrieved 2021-02-01.
  3. ↑ Sebag, J. (2020-11-01). "Vitreous and Vision Degrading Myodesopsia". Progress in Retinal and Eye Research. 79: 100847. doi:10.1016/j.preteyeres.2020.100847. ISSN 1350-9462. PMID 32151758 Check |pmid= value (help). Unknown parameter |s2cid= ignored (help)
  4. ↑ 4.0 4.1 McKinney, Sean (9 April 2020). "Daring to Treat Floaters". www.reviewofophthalmology.com. Retrieved 2021-02-02. Unknown parameter |url-status= ignored (help)
  5. ↑ "University level care in a private setting | 92647". Retina Specialists Huntington Beach 92647. Retrieved 2021-02-01.
  6. ↑ Sebag, J. (1989). The Vitreous. doi:10.1007/978-1-4613-8908-8. ISBN 978-1-4613-8910-1. Unknown parameter |s2cid= ignored (help) Search this book on
  7. ↑ Sebag, J., ed. (2014). Vitreous. doi:10.1007/978-1-4939-1086-1. ISBN 978-1-4939-1085-4. Search this book on
  8. ↑ Sebag, J. (2020-11-01). "Vitreous and Vision Degrading Myodesopsia". Progress in Retinal and Eye Research. 79: 100847. doi:10.1016/j.preteyeres.2020.100847. ISSN 1350-9462. PMID 32151758 Check |pmid= value (help). Unknown parameter |s2cid= ignored (help)
  9. ↑ Mamou, J.; Wa, C. A.; Yee, K. M. P.; Silverman, R. H.; Ketterling, J. A.; Sadun, A. A.; Sebag, J. (2015-01-22). "Ultrasound-Based Quantification of Vitreous Floaters Correlates with Contrast Sensitivity and Quality of Life". Investigative Ophthalmology & Visual Science. 56 (3): 1611–1617. doi:10.1167/iovs.14-15414. ISSN 0146-0404. PMC 4554261. PMID 25613948.
  10. ↑ Sebag, Jerry; Yee, Kenneth M. P.; Wa, Christianne A.; Huang, Laura C.; Sadun, Alfredo A. (June 2014). "VITRECTOMY FOR FLOATERS: Prospective Efficacy Analyses and Retrospective Safety Profile". RETINA. 34 (6): 1062–1068. doi:10.1097/IAE.0000000000000065. ISSN 0275-004X. PMID 24296397. Unknown parameter |s2cid= ignored (help)
  11. ↑ Sebag, Jerry; Yee, Kenneth M. P.; Wa, Christianne A.; Huang, Laura C.; Sadun, Alfredo A. (June 2014). "VITRECTOMY FOR FLOATERS: Prospective Efficacy Analyses and Retrospective Safety Profile". RETINA. 34 (6): 1062–1068. doi:10.1097/IAE.0000000000000065. ISSN 0275-004X. PMID 24296397. Unknown parameter |s2cid= ignored (help)
  12. ↑ Curriculum Vitae - Dr Sebag. Available at https://www.vmrinstitute.com/wp-content/uploads/2020/09/Sebag-CV-Aug-2020-.pdf (Accessed 02/02/2021)
  13. ↑ "Heed Fellows || The Heed Foundation". www.heed.org. Archived from the original on 2021-02-06. Retrieved 2021-02-01.
  14. ↑ McGrath, Dermot (1 October 2019). ""VITRECTOMY FOR MYODESOPSIA Vitreous floaters - from nuisance to disease"". EuroTimes. Retrieved 2 February 2021. Unknown parameter |url-status= ignored (help)
  15. ↑ "About the VDM Project - VDM research | Unite for clear vision". Retrieved 2021-02-02.
  16. ↑ "Terra Nuova Aprile 2021". www.terranuova.it (in italiano). Retrieved 2021-04-23.
  17. ↑ Robinson, Rita (31 August 2014). "Trail Upgrades OK'd for Top of the World". Laguna Beach Independent. Retrieved 6 February 2021. Unknown parameter |url-status= ignored (help)
  18. ↑ "Guggenheim Prizes | News | The Harvard Crimson". www.thecrimson.com. Retrieved 2021-02-02.
  19. ↑ "J. Sebag :: Doctor - Huntington Beach, California (CA) :: Doctor Profile :: Super Doctors". www.superdoctors.com. Retrieved 2021-02-01.
  20. ↑ "Heed Fellows || The Heed Foundation". www.heed.org. Archived from the original on 2021-02-06. Retrieved 2021-02-01.


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