Kateria Ahrendt
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| Kateria Ahrendt | |
|---|---|
| Born | |
| 🎓 Alma mater | University of California, Berkeley |
| 💼 Occupation | |
Kateri Ann Ahrendt is an Associate Professor of Chemistry at Regis University.
Early life and education[edit]
Ahrendt was born on June 1, 1975 (age 46). She currently resides in Longmont, Colorado and works as an Associate Professor of Chemistry at Regis College. Ahrendt did an internship in chemistry at the University of Michigan in 1997,[citation needed] and in 2000 she earned a master's degree [1][better source needed] She earned her Ph.D. in chemistry at the University of California, Berkeley in 2003.[2]
Teaching[edit]
Ahrendt teaches courses as an Associate Professor at Regis University. She began teaching at Regis University in May 2009 and has worked as a professor for 12 years. She has taught courses in General Chemistry, Organic Chemistry, Advanced Organic Chemistry, Synthesis and Characterization Laboratory, Chemistry for the Health-Related Sciences and Drugs of Use and Abuse.[3]
Research[edit]
Ahrendt worked as a Senior Research Scientist at Array BioPharma from May 2005 until January 2009. Her work involved Medicinal Chemistry. She worked on the design and synthesis of novel and potent inhibitors of miotic kinesin and B-raf kinase. Ahrendt identified viable multistep synthetic routes amenable for scale-up or target compounds.[citation needed] [patent 9,394,254 in 2016 and 8,324,257 in 2012)
Enantioselective organocatalytic Diels-Alder reaction[edit]
As a first-year graduate student Ahrendt worked with David MacMillan on asymmetric organocatalysts, specifically iminium ions.[4] This work led to a 2000 publication on the first highly enantioselective organocatalytic Diels-Alder reaction.[5] In 2021, MacMillan and Benjamin List went on to win the 2021 Nobel Prize in Chemistry for "for the development of asymmetric organocatalysis".[6]
Ahrendt et al. investigated the controlling the absolute stereochemistry of the Diels-Alder reaction to produce a chiral product from achiral diene and dienophile precursors.[citation needed]
Selected publications[edit]
- Ahrendt, Kateri A.; Borths, Christopher J.; MacMillan, David W. C. (1 May 2000). "New Strategies for Organic Catalysis: The First Highly Enantioselective Organocatalytic Diels−Alder Reaction". Journal of the American Chemical Society. 122 (17): 4243–4244. doi:10.1021/ja000092s.
- Thalji, R. K.; Ahrendt, K. A.; Bergman, R. G.; Ellman, J. A. (1 October 2001). "Annulation of Aromatic Imines via Directed C−H Activation with Wilkinson's Catalyst". Journal of the American Chemical Society. 123 (39): 9692–9693. doi:10.1021/ja016642j. PMID 11572698.
- Ahrendt, Kateri A.; Bergman, Robert G.; Ellman, Jonathan A. (1 April 2003). "Synthesis of a Tricyclic Mescaline Analogue by Catalytic C−H Bond Activation". Organic Letters. 5 (8): 1301–1303. doi:10.1021/ol034228d. PMID 12688744.
- Ahrendt, Kateri A.; Williams, Robert M. (1 November 2004). "A Concise Asymmetric Synthesis of the ADE Fragment of Nakadomarin A". Organic Letters. 6 (24): 4539–4541. doi:10.1021/ol048126e. PMID 15548070.
References[edit]
- ↑ "Former members". Macmillan Group. Retrieved 2022-05-10.
- ↑ Ahrendt, Kateri Ann (2003). The first highly enantioselective organocatalytic diels-alder reaction: Development of antibiotics against vancomycin-resistant bacteria : Annulation of aromatic imines via directed C-H bond activation (Thesis). OCLC 54664324.
- ↑ ""Regis University"". Regis University. Retrieved 10 October 2021.
- ↑ Durrani, Jamie (15 October 2021). "How organocatalysis won the Nobel prize". Chemistry World. Retrieved 2022-03-22.
- ↑ Ahrendt, K. A.; Borths, C. J.; MacMillan, D. W. C. (2000). "New Strategies for Organic Catalysis: The First Highly Enantioselective Organocatalytic Diels−Alder Reaction". Journal of the American Chemical Society. 122 (17): 4243–4244. doi:10.1021/ja000092s.
- ↑ "The Nobel Prize in Chemistry 2021". 2021. Retrieved March 3, 2022.
External links[edit]
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