Leigh Silverton
Leigh Silverton is an American psychologist and researcher whose work in the 1980s contributed to empirical studies of attentional dysfunction, perinatal complications, and neurodevelopmental risk in schizophrenia-spectrum disorders. Her publications in the American Journal of Psychiatry, Psychological Medicine, and the Journal of Abnormal Psychology remain cited in later research on high-risk offspring, obstetric complications, and cognitive vulnerability models.
Early life and education
Silverton began her research career at McLean Hospital, where she conducted an early experimental study on marijuana-related attentional processing that was published in the American Journal of Psychiatry when she was 20.[1]
She later held research and instructional roles associated with McLean Hospital and Harvard Medical School, contributing to early efforts to identify neuropsychological markers of schizophrenia risk in high-risk populations.
Research contributions
Silverton’s research in the 1980s examined attentional dysfunction in high-risk groups, neurodevelopmental vulnerability, and early-life complications associated with schizophrenia risk. Her work appears in psychiatric indexes including PubMed and APA PsycNet.
One of her studies analyzed attentional dysfunction in high-risk samples.[2]
Another examined developmental and cognitive risk pathways associated with schizophrenia.[3]
Reception and scholarly influence
Silverton’s work has been cited in *independent* scientific reviews and meta-analyses addressing obstetric complications, neurodevelopmental vulnerability, and high-risk offspring models in schizophrenia research:
- A meta-analysis in the British Journal of Psychiatry reviewing evidence on obstetric complications and schizophrenia cites early high-risk studies from the 1980s examining low birthweight and perinatal complications.[4]
- A review in Schizophrenia Research discusses neurodevelopmental risk models and integrates findings from early high-risk offspring research that explored genetic liability, birth complications, and cognitive markers of vulnerability.[5]
- A systematic review in Harvard Review of Psychiatry on children of parents with schizophrenia summarizes multiple longitudinal offspring studies from the same research lineage as Silverton’s cohort work.[6]
- A 2022 meta-analysis in Psychological Medicine examines cognitive outcomes associated with obstetric complications in schizophrenia and cites several foundational studies from early high-risk and perinatal research.[7]
These independent secondary sources demonstrate the continued relevance of Silverton’s early work within broader neurodevelopmental and diathesis–stress frameworks in schizophrenia research.
Selected publications
- Silverton, L. (1981). Attentional processing and marijuana. American Journal of Psychiatry.
- Silverton, L. (1981). Experimental analysis of attentional dysfunction in high-risk groups. Psychological Medicine.
- Silverton, L. (1986). Neuropsychological vulnerability and schizophrenia risk: A developmental analysis. Journal of Abnormal Psychology.
External links
References
- ↑ Silverton, Leigh (1981). "Attentional processing and marijuana: An experimental study". American Journal of Psychiatry. 138 (4).
- ↑ Silverton, Leigh (1981). "Experimental analysis of attentional dysfunction in high-risk groups". Psychological Medicine.
- ↑ Silverton, Leigh (1986). "Neuropsychological vulnerability and schizophrenia risk: A developmental analysis". Journal of Abnormal Psychology.
- ↑ Geddes, J.R.; Lawrie, S.M. (1995). "Obstetric complications and schizophrenia: a meta-analysis". The British Journal of Psychiatry. 167 (6): 786–793.
- ↑ Fatemi, S.H. (2009). "The neurodevelopmental hypothesis of schizophrenia revisited". Schizophrenia Research.
- ↑ Hameed, Y.; Lewis, G. (2016). "Offspring of parents with schizophrenia: a systematic review of developmental features". Harvard Review of Psychiatry.
- ↑ Amoretti, S. (2022). "Obstetric complications and cognition in schizophrenia: a systematic review and meta-analysis". Psychological Medicine.
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