Liviu M. Mirica
Liviu M. Mirica is the Janet and William H. Lycan Professor of Chemistry at the University of Illinois at Urbana-Champaign known for his work in organometallic chemistry and nickel-based catalysis. He was elected in 2018 as a Fellow of the Royal Society of Chemistry, and in 2022 as a Fellow of the American Association for the Advancement of Science.[1] His research interests include using synthetic inorganic and organometallic chemistry to study novel transition metal complexes with applications for sustainable catalysis.[2][3] He has also worked on developing bifunctional diagnostic and therapeutic agents for amyloid beta disorders such as Alzheimer’s disease and continues to investigate the roles of transition metal ions in neurodegenerative diseases.[4][5]
| Liviu M. Mirica | |
|---|---|
| File:Mirica-1.jpgMirica-1.jpg | |
| Born | |
| 🎓 Alma mater | California Institute of Technology (B.A.) (1999) Stanford University (Ph.D.) (2005) |
| 💼 Occupation | |
| 🌐 Website | https://mirica.web.illinois.edu/ |
Early life and education
Mirica studied chemistry as an undergraduate at California Institute of Technology in the lab of Harry B. Gray, where he received his B.A. in 1999. He continued his studies at Stanford University where he received his Ph.D. in 2005 under the guidance of T. Daniel P. Stack. He continued his work as a NIH postdoctoral fellow at University of California, Berkeley, working with Judith P. Klinman.
Career
Independent career
Mirica began his independent career in 2008, joining the Department of Chemistry faculty at Washington University in St. Louis. In 2013, he was the recipient of the National Science Foundation CAREER Award. In 2014, he was the recipient of the Organometallics Young Investigator Fellowship from the ACS Division of Inorganic Chemistry.[6][7][8] In 2019, he moved to the University of Illinois at Urbana-Champaign to join the faculty as a Janet and William H. Lycan Professor of Chemistry. He is also a professor in Biomedical and Translational Sciences and at the Beckman Institute for Advanced Science and Technology.[9]
Research
His group at the University of Illinois focuses on the fields of synthetic inorganic and organometallic chemistry as well as chemical biology. He is known for his study of novel transition metal complexes that can mediate multi-electron redox processes relevant to renewable energy.[10][11][12] Specifically, he has investigated the aerobic oxidative carbon-carbon coupling catalyzed by high-valent late transition metal complexes such as nickel and palladium, as well as the catalytic oxidative C-H functionalization and C-C/C-heteroatom bond formation reactions using sustainable oxidants.[13][14][15] He also applies his work to chemical biology, where he investigates the role of transition metal ions in the aggregation of amyloid β peptides in Alzheimer’s disease. He has developed both bifunctional metal-binding as well as metal-containing compounds for applications as therapeutic and diagnostic agents for Alzheimer's disease.[16]
References
- ↑ "2022 AAAS Fellows | American Association for the Advancement of Science (AAAS)". www.aaas.org. Retrieved 2023-05-08.
- ↑ "Mimicking biological enzymes may be key to hydrogen fuel production". ScienceDaily. Retrieved 2023-05-08.
- ↑ "New Molecule Sets Stage for Nickel as a 'Greener' Photocatalyst". Lab Manager. Retrieved 2023-05-08.
- ↑ Community, Nature Portfolio Chemistry (2022-03-19). "Deciphering the mechanism of the Ni-photocatalyzed C‒O cross-coupling reaction using a tridentate pyridinophane ligand". Nature Portfolio Chemistry Community. Retrieved 2023-05-08.
- ↑ "Team uses copper to image Alzheimer's aggregates in the brain". EurekAlert!. Retrieved 2023-05-08.
- ↑ "Division of Inorganic Chemistry's Young Investigator Awards". cen.acs.org. Retrieved 2023-05-08.
- ↑ "ECA winner 2020Liviu Mirica". sbic.memberclicks.net. Retrieved 2023-05-08.
- ↑ "St. Louis Section–American Chemical Society » Liviu Mirica snags 2016 Saint Louis Award". Retrieved 2023-05-08.
- ↑ "Liviu M. Mirica | Chemistry at Illinois". chemistry.illinois.edu. Retrieved 2023-05-08.
- ↑ Na, Hanah; Mirica, Liviu M. (2022-03-14). "Deciphering the mechanism of the Ni-photocatalyzed C‒O cross-coupling reaction using a tridentate pyridinophane ligand". Nature Communications. 13 (1): 1313. doi:10.1038/s41467-022-28948-8. ISSN 2041-1723. PMC 8921334 Check
|pmc=value (help). PMID 35288558 Check|pmid=value (help). - ↑ Chakrabarti, Sagnik; Sinha, Soumalya; Tran, Giang N.; Na, Hanah; Mirica, Liviu M. (2023-02-17). "Characterization of paramagnetic states in an organometallic nickel hydrogen evolution electrocatalyst". Nature Communications. 14 (1): 905. Bibcode:2023NatCo..14..905C. doi:10.1038/s41467-023-36609-7. ISSN 2041-1723. PMC 9938211 Check
|pmc=value (help). PMID 36807358 Check|pmid=value (help). - ↑ Berners-Price, Sue (2020-09-01). "Note from the President". JBIC Journal of Biological Inorganic Chemistry. 25 (6): 925–926. doi:10.1007/s00775-020-01811-1. ISSN 1432-1327. PMC 7487442 Check
|pmc=value (help). PMID 32926232 Check|pmid=value (help). - ↑ Comprehensive Coordination Chemistry. III. Edwin C. Constable, Gerard Parkin, Lawrence Que. Amsterdam, Netherland. 2021. ISBN 978-0-08-102689-2. OCLC 1261764185. Search this book on
- ↑ Yoksoulian, Lois. "Mimicking biological enzymes may be key to hydrogen fuel production". news.illinois.edu. Retrieved 2023-05-08.
- ↑ "NSF Award Search: Award # 1925751 - Stereocontrolled and Aerobic Oxidative Reactions at High-Valent Nickel Centers". www.nsf.gov. Retrieved 2023-05-08.
- ↑ "New compound significantly reduces multiple pathologies linked to Alzheimer's disease". News-Medical.net. 2020-05-08. Retrieved 2023-05-08.
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