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MNI Coordinate System

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The MNI coordinate system, also referred to as MNI space, are multiple stereotaxic brain coordinate systems created by the Montreal Neurological Institute and Hospital.[1][2][3] Similar to the Talairach coordinates, MNI coordinates can be used to describe the location of particular brain structures, without having to take into account any individual brain differences. However, as the Talairach system is unrepresentative of the population at large, MNI coordinates were developed from MRI data garnered from many individuals, in an effort to create a neural coordinate system that could be more generalizable. MNI coordinates have been matched to Talairach coordinates to allow landmarks to correspond.[4]

The original MNI space was MNI 305, which was created from 305 Talairach aligned images, from which a mean brain image was taken.[1][5] MNI 152 (also known as ICBM 152) was created later with higher resolution MRI images that were registered to MNI 305, and from which a mean was taken.[2][3][5] MNI 152 is itself further made up of different atlases, with different constraints, such as linearly/non-linearly aligned and symmetric or non-symmetric brain hemispheres.[2]

References

  1. 1.0 1.1 Evans, A.C.; Collins, D.L.; Mills, S.R.; Brown, E.D.; Kelly, R.L.; Peters, T.M. (1993). "3D statistical neuroanatomical models from 305 MRI volumes". 1993 IEEE Conference Record Nuclear Science Symposium and Medical Imaging Conference. IEEE. pp. 1813–1817. doi:10.1109/NSSMIC.1993.373602. ISBN 978-0-7803-1487-0. Unknown parameter |s2cid= ignored (help) Search this book on
  2. 2.0 2.1 2.2 Fonov, Vladimir; Evans, Alan C.; Botteron, Kelly; Almli, C. Robert; McKinstry, Robert C.; Collins, D. Louis (2011-01-01). "Unbiased average age-appropriate atlases for pediatric studies". NeuroImage. 54 (1): 313–327. doi:10.1016/j.neuroimage.2010.07.033. ISSN 1053-8119. PMC 2962759. PMID 20656036.
  3. 3.0 3.1 Fonov, VS; Evans, AC; McKinstry, RC; Almli, CR; Collins, DL (2009-07-01). "Unbiased nonlinear average age-appropriate brain templates from birth to adulthood". NeuroImage. 47: S102. doi:10.1016/S1053-8119(09)70884-5. ISSN 1053-8119. Unknown parameter |s2cid= ignored (help)
  4. Huettel, Scott A.; Song, Allen W.; McCarthy, Gregory (2004). Functional Magnetic Resonance Imaging (1st ed.). Sinauer Associates, Inc. p. 273. ISBN 0-87893-288-7. Search this book on
  5. 5.0 5.1 Poldrack, Russell A.; Mumford, Jeanette A.; Nichols, Thomas E. (2011-06-01). Handbook of Functional MRI Data Analysis. Cambridge University Press. pp. 305–306. doi:10.1017/cbo9780511895029. ISBN 978-0-521-51766-9. Search this book on


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