Massachusetts General Hospital Research Institute

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Massachusetts General Hospital Research Institute

The Massachusetts General Hospital Research Institute was formed in 2014 to support, promote and guide research at Massachusetts General Hospital (Mass General).

Mass General operates the largest hospital-based research program in the United States, with an annual budget of approximately $800 million. Research at Mass General is conducted in more than 30 departments, centers and institutes across the hospital.

The Mass General research community includes more than 8,000 people working on the hospital’s main campus in downtown Boston, at two research buildings in the Charlestown Navy Yard, and at various locations throughout Boston and Cambridge. The total research footprint is over 1.2 million square feet.

Externally, the Research Institute is intended to serve as a “front door” through which the hospital’s research leadership can engage federal and foundation funding sources, collaborators, and the industrial, venture capital, and philanthropic communities. Internally, the Institute is working to build the hospital’s translational research programs and to facilitate collaborative research efforts with other institutions.

In addition to establishing the Research Institute as an overarching matrix for structure and operations, the hospital also established a new Translational and Clinical Research Center and formalized its support for the Partners Biobank—a multi-institutional repository of blood samples from consented patients that can be used for medical research.

Mass General is the original and largest teaching hospital of Harvard Medical School. It is the third oldest general hospital in the United States and the oldest and largest hospital in New England with over 1,000 beds. Innovation in biomedical research at the hospital has a long and storied history that continues today. In 1846, surgeons at Mass General made medical history by conducting the first public demonstration of surgery using ether as a general anesthetic.

Mass General was also the first hospital in the United States to generate an X-ray for medical diagnosis in 1896, the first to start a tumor clinic for the study of cancer in 1925, and the first to reattach a severed human limb in 1962.

Our researchers perfected the use of the Pap smear as a tool to diagnose cervical cancer in 1946, partnered with doctors and scientists from the Massachusetts Institute of Technology and the Shriners Burn Institute to create the first artificial skin from living cells in 1981, and discovered the first gene associated with inherited, early-onset Alzheimer's disease in 1987.

In 2009, Jack W. Szostak, PhD, from the Mass General Department of Molecular Biology, was one of three recipients of the Nobel Prize in Medicine “for the discovery of how chromosomes are protected by telomeres and the enzyme telemerase.”

In 2016, Mass General was named the #1 heathcare organization for research by the Nature Index, which tracked the number of articles published in high-impact research journals from February 2016 to January 2016.

Leadership

The Mass General Research Institute is led by the Research Institute Steering Committing (RISC), which is comprised of the hospital’s president, the senior vice president for research, the chair, vice chair and past chair of the Executive Committee on Research, the scientific director of the Research Institute, the director of the Division of Clinical Research, and the chiefs of the departments of surgery and medicine.

Research and science policy at Mass General is developed and guided by the Executive Committee on Research (ECOR), a committee officially chartered for this purpose by the hospital’s General Executive Committee.

Departments, Centers and Institutes

The Mass General Research Institute serves as the overarching matrix for more than 30 departments, centers and institutes and centers at Massachusetts General Hospital.

Departments

• Anesthesia, Critical Care and Pain Medicine
• Dermatology
• Emergency Medicine
• Medicine
• Molecular Biology
• Neurology
• Neurosurgery
• Nursing
• Obstetrics and Gynecology
• Ophthalmology (at Mass Eye and Ear Infirmary)
• Oral and Maxillofacial Surgery
• Orthopaedics
• Otolaryngology
• Pathology
• Pediatrics
• Physical Medicine and Rehabilitation (at Spaulding Hospital)
• Psychiatry
• Radiology
• Radiation Oncology
• Surgery
• Urology

Thematic Centers

• Center for Computational and Integrational Biology
• Center for Human Genetic Research
• Center for Regenerative Medicine
• Center for Systems Biology
• Wellman Center for Photomedicine

Multi-Institutional Centers

• Athinoula A. Martinos Center for Biomedical Imaging
• Center for the Integration of Medicine and Innovative Technology
• Center for Genomics, Vulnerable Populations and Health Disparities
• Center for Molecular Imaging Research
• The Home Base Program
• The Ragon Institute

Multi-Departmental Centers:

• The Mass General Cancer Center
• Critical Care Center
• Digestive Healthcare Center
• Heart Center
• Mass General Hospital for Children
• Transplant Center
• Vascular Center

External links

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