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Massoud Vosough

From EverybodyWiki Bios & Wiki





portrait photo of Professor Massoud Vosough taken in 2025
portrait of Professor Massoud Vosough, 2025.
Massoud Vosough
Born
🎓 Alma materTehran University of Medical Sciences (MD); Pasteur Institute of Iran (PhD, joint); Royan Institute (PhD, joint); Karolinska Institute (postdoctoral fellow)
💼 Occupation
Known forLiver regenerative medicine; bioengineered liver organoids

Massoud Vosough is an Iranian physician and researcher specializing in regenerative medicine, stem cell biology, cancer immunotherapy, and liver diseases. He is an Associate Professor of Medicine at the Royan Institute for Stem Cell Biology and Regenerative Medicine in Tehran, where he heads the Department of Regenerative Medicine.

Early life and education

Massoud Vosough is a graduate of general biology from Kamal High School in Tehran, Iran. He earned his MD from Tehran University of Medical Sciences. He completed a joint PhD program in biomedical research at the Pasteur Institute of Iran and the Royan Institute in Tehran (2008–2013). He undertook two postdoctoral fellowships in cell transplantation and regenerative medicine at Karolinska Institute in Sweden (2013–2016).[1][2]

Career

At the Royan Institute [3], Massoud serves as an Associate Professor of Medicine and Head of the Regenerative Medicine Department. He has been a senior associate researcher at the Karolinska Institute [4] since 2013. In 2023, he was appointed chairman of the National Board in Applied Cell Science at Iran’s Ministry of Health and Medical Education. He holds visiting professorships at the Institute of Regenerative Medicine at First Moscow Medical University (since 2019) and at Maranatha Christian University in Indonesia (since 2024). Massoud Vosough became an adjunct professor at Tehran University of Medical Sciences in 2025.

He has been an organizer and instructor of regenerative medicine courses in Iran, Russia, Sweden, Germany, and Indonesia, supervised national and international graduate students, and contributed to fellowship programs and advanced training courses. In translational and regulatory work, he served as Deputy Director for Quality and Regulatory Affairs at Cell Tech Pharmed Company (2016–2025), where he registered the first national advanced therapy medicinal products (ATMPs) in Iran.[5][6][7][8]

Research

Massoud Vosough’s research spans liver regenerative medicine, including bioengineered liver organoids for drug screening and disease modeling, stem/progenitor cell-based approaches to liver fibrosis and cirrhosis, and immunotherapy using differentiation therapy in gastrointestinal and liver cancers[9]. Additional areas include regenerative medicine for inflammatory bowel diseases, pluripotent stem cell biology and reprogramming, and production of ATMPs. He has co-authored numerous peer-reviewed publications in hepatology, pharmacology, and cell biology journals.[10][11][12][13][14][15][16]

Selected publications

Naserkhaki, R; Fotouhi, A; Piryaei, A; Tahamtani, Y; Vosough, M (2025). "Turmerone-loaded nanocarriers effectively induced apoptosis and attenuated cancerous phenotype in hepatocellular carcinoma models". Colloids and Surfaces B: Biointerfaces. 254. doi:10.1016/j.colsurfb.2025.114830. PMID 40441040 Check |pmid= value (help).

Vosough, M; Shokouhian, B; Heidari, Z; Seydi, H; Hassan, M; Najimi, M (2025). "Role of mitogens in normal and pathological liver regeneration". Hepatology Communications. 9 (5). doi:10.1097/HC9.0000000000000692. PMC 12045551 Check |pmc= value (help). PMID 40304568 Check |pmid= value (help).

Haghir-Sharif-Zamini, Y; Zarrabi, A; Vosough, M (2025). "c-FLIP/Ku70 complex as a potential molecular target for apoptosis induction in hepatocellular carcinoma". Archives of Biochemistry and Biophysics. 765. doi:10.1016/j.abb.2025.110306. PMID 39818348 Check |pmid= value (help). Unknown parameter |article-number= ignored (help)

Heydari, Z; Gramignoli, R; Nüssler, A; Szkolnicka, D; Hay, D C; Najimi, M; Vosough, M (2025). "Standard protocols for characterising primary and in vitro-generated human hepatocytes". Journal of Cellular and Molecular Medicine. 29 (3). doi:10.1111/jcmm.70390. PMC 11798750 Check |pmc= value (help). PMID 39910642 Check |pmid= value (help). Unknown parameter |article-number= ignored (help)

Fathi, M; Vakili, K; Hassan, M; Rismani, E; Vosough, M (2024). "GPC-3 in hepatocellular carcinoma: a novel biomarker and molecular target". Experimental Cell Research. 444 (2). doi:10.1016/j.yexcr.2024.114391. PMID 39725192 Check |pmid= value (help). Unknown parameter |article-number= ignored (help)

Hendi, Z; Asadi Sarabi, P; Hay, D C; Vosough, M (2023). "XBP1 as a novel molecular target to attenuate drug resistance in hepatocellular carcinoma". Expert Opinion on Therapeutic Targets. 27 (12): 1207–1215. doi:10.1080/14728222.2023.2293746. PMID 38078890 Check |pmid= value (help).

Seydi, H; Nouri, K; Rezaei, N; Tamimi, A; Hassan, M; Mirzaei, H; Vosough, M (2023). "Autophagy orchestrates resistance in hepatocellular carcinoma cells". Biomedicine & Pharmacotherapy. 161. doi:10.1016/j.biopha.2023.114487. PMID 36963361 Check |pmid= value (help). Unknown parameter |article-number= ignored (help)

Miri-Lavasani, Z; Shokouhian, B; Vosough, M (2022). "Conjugated linoleic acid treatment attenuates cancerous phenotype in hepatocellular carcinoma cells". Journal of Cellular Physiology. doi:10.1155/2022/1850305. PMC 9484933 Check |pmc= value (help). PMID 36132168 Check |pmid= value (help).

Awards and honours

  • Invited speaker and chairman, IUIS2025, Vienna, Austria (2025).
  • Scientific chair, WANA International Congress in Regenerative Medicine, Kish (2025).[17]
  • Supervisor, joint international PhD program with KU Leuven, Belgium (2021–2025).
  • Recipient of international research grants (including DAAD from Iran-Germany and Iran–Russia collaborations).
  • Featured article cover pages in journals such as Cell Journal , Trends in Endocrinology & Metabolism, and Journal of Molecular Medicine.
  • First market authorization record reported for ATMP-based commercial products in Iran (2023).
  • Best Abstract, International Society for Differentiation (2012).

External links

References

  1. ↑ "CV" (PDF).
  2. ↑ "royancell".
  3. ↑ "Royan Institute".
  4. ↑ "Karolinska Institutet".
  5. ↑ "CV" (PDF).
  6. ↑ "linkedin".
  7. ↑ "TV Interview".
  8. ↑ "Aparat interview".
  9. ↑ "CV" (PDF).
  10. ↑ "google scholar".
  11. ↑ "Researchgate".
  12. ↑ "scopus".
  13. ↑ "ORCID".
  14. ↑ "academia".
  15. ↑ "isid_research".
  16. ↑ "Aparat interview".
  17. ↑ "WANA Scientific".


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