Medical Electronic Systems, LLC
| Private | |
| ISIN | 🆔 |
| Industry | Medical Diagnostics |
| Founded 📆 | 1993 |
| Founder 👔 | |
| Headquarters 🏙️ | Los Angeles, California, United States |
Area served 🗺️ | Worldwide |
| Products 📟 | Sperm Quality Analyzers (SQA), YO Home Sperm Test |
| Members | |
Number of employees | |
| 🌐 Website | www |
| 📇 Address | |
| 📞 telephone | |
Medical Electronic Systems, LLC (MES) is an American medical diagnostics company headquartered in Los Angeles, California, that develops and manufactures automated semen analysis instrumentation for clinical and consumer markets.[1] Founded in 1993, MES produces the Sperm Quality Analyzer (SQA) series for hospital and laboratory use.[2] In 2017, the company released the YO Home Sperm Test, the first smartphone-based at-home semen analysis device to receive FDA clearance, which was covered by TechCrunch upon launch and subsequently cited by Yale Medicine and the Cleveland Clinic as an accessible option for early male fertility screening.[3][4][5][6] In 2025, the company entered a technology partnership with Femasys Inc. (NASDAQ: FEMY), a publicly traded biomedical company, to provide sperm analysis technology for the FemSperm Analysis Kit.[7]
History
Medical Electronic Systems was founded in May 1993 to develop automated semen analysis instrumentation.[2] The company's first product, the SQA-II-CP, was launched in April 1996.[2] A United States subsidiary, Medical Electronic Systems, LLC, was incorporated in January 2005.[2]
The SQA-V sperm quality analyzer, which became the company's flagship clinical laboratory product, was launched in July 2001.[2] The SQA-Vision, an upgraded platform incorporating video microscopy capabilities, was released in February 2015.[2] The SQA-iO, a compact web-based analyzer for lower-volume laboratory settings, launched in August 2020 and received FDA 510(k) clearance under submission number K220828.[2][8]
In September 2017, MES expanded into consumer digital health with the launch of the YO Home Sperm Test, the first smartphone-based at-home semen analysis device to receive FDA clearance.[3][4] The launch was covered by TechCrunch, which noted the device's ability to measure motile sperm concentration using smartphone camera technology, distinguishing it from earlier at-home tests limited to sperm count measurement.[3] Yale Medicine subsequently identified the YO as one of three FDA-cleared at-home sperm tests available to patients,[5] and the Cleveland Clinic published an independent editorial describing it as a user-friendly and accurate device for at-home semen analysis.[6] In December 2024, an updated version designated the YO 3.0 received FDA 510(k) clearance under submission number K241628, expanding semen parameter reporting to five quantitative measures.[9]
In September 2025, Femasys Inc. (NASDAQ: FEMY), a publicly traded biomedical company, announced a formal partnership with MES to provide sperm analysis technology for the FemSperm Analysis Kit, enabling gynecologists to perform in-office sperm preparation and analysis as part of the FemaSeed Intratubal Insemination treatment workflow.[7]
Technology and Instrumentation
Clinical semen evaluation has historically relied on manual optical microscopy, a process noted in medical literature for inter-operator variability and subjectivity.[1][10] MES instrumentation replaces manual counting grids by utilizing electro-optical signal processing, localized computational algorithms, and video microscopy. These systems measure light scattering fluctuations caused by cell movement within a calibrated capillary path to quantify sample attributes.[11][12] The approach eliminates the subjective variables inherent to manual assessment, including operator fatigue, inconsistent staining protocols, and inter-laboratory variability.[10][13]
Laboratory Analyzers
The company's primary laboratory product line consists of the Sperm Quality Analyzer (SQA) series, including the SQA-V, SQA-Vision, SQA-iO, and SQA-iOw systems. These systems are used in hospitals and reference laboratories to calculate total sperm concentration, progressive motility subdivisions, normal morphology percentages, and functional sperm velocity tracking variables within automated testing cycles of approximately 75 seconds.[1][14][10] The standalone instrumentation integrates with electronic medical record (EMR) and Laboratory Information Systems (LIS) to manage clinical documentation workflows.[1]
SQA-V and SQA-Vision
The SQA-V has been validated across multiple independent institutions. A double-blind prospective study at the Cleveland Clinic Foundation found that the SQA-V can be used interchangeably with manual semen analysis for sperm concentration and motility, with precision coefficients of variation substantially lower than manual methods (1.4% vs. 6.0% for concentration).[10] A separate Cleveland Clinic abstract demonstrated that sperm concentration readings from the SQA-V correlated at r=0.985 with established standard values, with no systematic differences detected.[15] Motility results from the SQA-V showed narrower confidence intervals than either manual operator, with the conventional manual method prone to overestimation.[16]
A validation study conducted at two Israeli hospitals across 539 semen samples confirmed that the SQA-V can reliably replace manual semen analysis, with concentration regression slopes of 1.00, regression coefficients of 0.99, and CVs below 7% for all parameters.[17] An independent six-center Quality Assurance Program conducted by IVF Australia confirmed high precision across laboratories, with intra-lab CVs averaging 2.7% and inter-lab CVs of 6.2%.[18]
A retrospective study published in the Scandinavian Journal of Clinical and Laboratory Investigation analyzing 1,130 samples collected between October 2019 and October 2023 found no statistically significant difference between the SQA-V and manual assessment for all measured semen parameters, with correlation coefficients ranging from rho=0.81 for morphology to rho=0.98 for concentration and round cell count.[19] A prospective double-blind study at the University Hospital of Nantes comparing the SQA-Vision against the CASA-based Sperm Class Analyzer (Microptic SCA) found that both automated systems achieved acceptable analytical performance comparable to manual assessment, with the SQA-Vision demonstrating 93.6% specificity across all sperm parameters versus 80.3% for the CASA system, and mean sperm concentration, progressive motility, and total motility were not statistically different between the three methods.[13][20]
A study from IVF Australia comparing 100 fresh semen samples found that the SQA-V demonstrated substantially lower intra-sample variation than human operators, with a sperm concentration CV of 2.3% versus 12.8% for manual analysis, and concluded that manual methods significantly overestimate progressive motility.[21]
Studies confirmed that the sperm velocity assessment parameter of the SQA-V correlated significantly with CASA estimates including curvilinear velocity, straight-line velocity, and average path velocity.[14]
A study at Overlook Medical Center (Atlantic Health System), presented at the 2011 AACC Annual Meeting, found that implementing the SQA-V reduced semen analysis turnaround time from an average of 82 hours to under 3 hours, freeing 0.5 FTE annually and reducing labor costs by $14,560.[12]
SQA-iO and SQA-iOw
The SQA-iO received FDA 510(k) clearance under submission number K220828.[8] The SQA-iOw received FDA 510(k) clearance under submission number K243114[22] and is designed for point-of-care settings operating under CLIA-waived certification.
A study presented at ASRM 2024 evaluated the SQA-iOw in the hands of CLIA-waived Registered Nurse operators across 398 donor semen samples at three sites. The SQA-iOw demonstrated accuracy of 96% or higher for sperm concentration, motile sperm concentration, progressively motile sperm concentration, motility, progressive motility, and morphology when compared to professional SQA-V operators, with precision CVs below 7.5% across 168 replicates.[23]
Sperm Motility Index and Fertility Prediction
The Sperm Motility Index (SMI), a composite parameter calculated by SQA instrumentation, has been investigated as a predictor of male fertility outcomes. A study at the University of Melbourne across 150 samples at three laboratories found strong correlations between SMI and manual sperm concentration, motility, abnormal morphology, and CASA estimates including curvilinear and straight-line velocity, with SMI covariates accounting for 85.5% of SMI variance by multiple regression analysis.[24]
A study at Ghent University Hospital across 223 samples and multiple ART treatment cycles found that SMI values significantly correlated with sperm concentration, motility, and morphology, and that SMI both before and after sperm preparation had the highest area under the ROC curve for predicting pregnancy occurrence alongside motile sperm concentration after preparation.[25] A study at Hyogo College of Medicine confirmed that higher SMI categories directly corresponded to higher IVF-ET fertilization rates: 76.0% for the "good" category versus 44.2% for "medium" and 34.7% for "poor" (p<0.001 for both comparisons).[26] Studies from Toyama Medical and Pharmaceutical University demonstrated that SMI values showed statistically significant correlations with multiple sperm function tests including the zona-free hamster ovum penetration test and the Penetrak test.[27]
A study across 207 patients confirmed that SQA variables for concentration and progressive motility showed high correlations with both conventional manual analysis and CASA estimates, supporting the SQA's utility as a clinical instrument for male infertility evaluation.[28] A study at Jichi Medical School across 71 fresh semen samples found significant correlations between SQA IIC variables and eight CASA estimates including sperm concentration, motility, motile sperm concentration, ALH, VCL, VSL, VAP, and rapid motility.[29]
A study investigating the use of the SQA in a digital method for sperm immobilization testing found 100% concordance in classification of positive and negative samples for sperm immobilizing antibodies when compared to the conventional microscopic method, with significant correlation in SI50 values (p<0.0001).[30]
At-Home Semen Analysis
In 2017, the company released the YO Home Sperm Test, an at-home semen analysis device. The launch was covered by TechCrunch, which described the YO as measuring motile sperm concentration using smartphone camera technology, distinguishing it from earlier at-home tests that measured only sperm count.[3] The platform consists of a clip-on hardware optical testing module that interfaces with a consumer smartphone or personal computer camera array.[11] The system uses an automated tracking algorithm to evaluate and output motile sperm concentration (MSC) variables along with a localized video capture of the specimen within approximately 20 minutes.[11] The YO Home Sperm Test was the first smartphone-based at-home semen analysis device to receive FDA clearance, operating under 510(k) submission number K161493.[31][3][4]
Yale Medicine identified the YO as one of three FDA-cleared at-home sperm tests available to patients, noting that it evaluates the number of moving sperm rather than count alone.[5] The Cleveland Clinic published an independent editorial describing the YO as a user-friendly and accurate device for at-home semen analysis, noting its potential to reduce barriers to male fertility evaluation.[6]
A subsequent version, the YO 3.0, expanded reporting to five quantitative semen parameters: sperm concentration, motility, progressive motility, MSC, and progressive MSC.[32][9]
Clinical Validation
A blinded prospective multi-site study across 316 amateur users and three professional laboratory technicians found that amateur YO users achieved accuracy greater than 97% versus professionally trained YO technicians, and greater than 95.7% accuracy versus the FDA-cleared SQA-V laboratory analyzer.[31] More than 96% of amateur participants rated the YO test directions as very or somewhat clear and easy to follow.[31]
A subsequent study presented at the ASRM 2024 Scientific Congress evaluated the YO 3.0 across 309 lay users at three sites and found correlations of 0.93 for concentration, 0.90 for motility, 0.88 for progressive motility, and 0.94 for both MSC and progressive MSC when compared to trained SQA operator results.[32] More than 90% of lay users described the testing experience as very clear and easy to follow across all usability categories.[32]
The WHO 6th Edition Laboratory Manual for the Examination and Processing of Human Semen acknowledges smartphone-based at-home sperm tests as having potential to become a useful means for men to seek early proper medical advice, investigation, and causal treatment.[32]
Veterinary Applications
MES instrumentation and the SQA platform have been applied in veterinary reproductive medicine across multiple species.
In poultry science, the Sperm Quality Index (SQI) generated by the SQA has been validated across multiple species and production scenarios. Studies at Mississippi State University demonstrated that the SQI accurately predicts broiler breeder fertility, with correlation coefficients of up to r=0.86 between SQI and live sperm concentration at optimal dilution rates, and r=0.75 with fertility.[33] An industry field trial using SQI-based male selection at 26 weeks of age resulted in 1.1% improvement in life-of-flock hatchability and produced 21,000 additional chicks across two SQI-selected houses over the control period.[34]
Research at Purdue University confirmed that the SQA responded to changes in turkey sperm concentration, viability, and motility across in vitro analyses, and accurately detected the decline in sperm quality associated with prolonged semen storage as well as age-related changes throughout a full production cycle.[35][36] A heat stress study found that elevated body temperature directly reduced sperm viability and SQI in a time- and temperature-dependent manner during in vitro incubation, confirming that hyperthermia alone contributes to heat stress infertility independent of systemic effects.[37]
A study at the Faculty of Veterinary Medicine at Ghent University validated the SQA-IIC for bull semen analysis, demonstrating good repeatability with coefficients of variation below 13% at concentrations between 35 and 705 million spermatozoa per mL, and significant correlations between SMI values and overall semen quality parameters at concentrations below 50 million spermatozoa per mL.[38]
A comparative study at Animal Health Care Flanders evaluating motility assessment of boar spermatozoa found that the SMI produced by the SQA-IIC correlated significantly with percentage motile spermatozoa measured by computer-assisted sperm analysis (r=0.71, p<0.05), while demonstrating poor agreement between independent visual assessors, confirming the inherent subjectivity of manual motility evaluation.[39]
Ancillary Products
QwikCheck Liquefaction Kit
The QwikCheck Liquefaction Kit contains alpha-chymotrypsin for treating highly viscous semen samples prior to analysis. A 2025 study published in Reproductive Medicine at University Hospitals / Case Western Reserve University found that alpha-chymotrypsin treatment of highly viscous semen significantly improved total motile sperm count (22.2 million vs. 11.6 million, p=0.0004) and motile sperm recovery rate (38.9% vs. 16.2%, p=0.00002) compared to untreated controls, with particular efficacy in patients with severely low sperm counts.[40] Fertilization and blastocyst rates in IVF cycles using alpha-chymotrypsin-treated samples were not significantly different from control cycles (87.8% vs. 85.5% fertilization rate; 56.4% vs. 53.2% blastocyst rate).[40]
MaleMan Semen Transport Kit
The MaleMan Semen Transport Kit is a Class I sterile specimen mailer and storage system registered under FDA Establishment Number 3003646592. It consists of single-use 5mL vials of semen preservative for specimen transportation and preservation, sold in packs of 50.
Industry Partnerships
In September 2025, Femasys Inc. (NASDAQ: FEMY), a publicly traded biomedical company, announced a partnership with MES to provide sperm analysis technology for the FemSperm Analysis Kit, enabling gynecologists to perform in-office sperm preparation and analysis as part of the FemaSeed Intratubal Insemination treatment.[7]
Regulatory Status
The clinical and consumer diagnostic systems developed by the company operate under various public health frameworks. The company's registered establishment number with the U.S. Food and Drug Administration is 3003646592, registered under Medical Electronic Systems Ltd. in Israel as both manufacturer and foreign exporter.
FDA-Cleared Devices
The following products have received FDA 510(k) premarket clearance:
| Proprietary Name | Classification | Product Code | Device Class | 510(k) Number |
|---|---|---|---|---|
| SQA-Vision; SQA-V; SQA Sperm Quality Analyzer | Semen Analysis Device | POV | 2 | K012352 |
| SQA-Vision; SQA-V; SQA Sperm Quality Analyzer | Semen Analysis Device | POV | 2 | K021746 |
| SQA-iO Sperm Quality Analyzer | Semen Analysis Device | POV | 2 | K220828 |
| SQA-iOw Sperm Quality Analyzer | Semen Analysis Device | POV | 2 | K243114 |
| YO Home Sperm Test | Semen Analysis Device | POV | 2 | K161493 |
| YO Home Sperm Test | Semen Analysis Device | POV | 2 | K241628 |
| QwikCheck Test Strips (Reagent Strips for Semen Analysis) | Semen Analysis Device | POV | 2 | K063864 |
| QwikCheck-Beads (Urinalysis Controls) | Urinalysis Controls (Assayed and Unassayed) | JJW | 1 | K041600 |
| QwikCheck-Beads (Semen Analysis QC Material) | Material, Quality Control, Semen Analysis | NRF | 2 | K041600 |
FDA-Listed Devices
The following products are registered with the FDA under Establishment Number 3003646592 and are listed as manufactured by Medical Electronic Systems Ltd.:
| Proprietary Name | Classification | Product Code | Device Class | Regulation Number |
|---|---|---|---|---|
| QwikCheck Liquefaction Kit | Trypsin | IBG | 1 | 864.4400 |
| QwikCheck Test Strip Quality Control | Urinalysis Controls (Assayed and Unassayed) | JJW | 1 | 862.1660 |
| QwikCheck DFI Kit | Wright's Stain | IAF | 1 | 864.1850 |
| QwikCheck Beads Precision and Linearity Kit; QwikCheck Proficiency and Training Kit | Material, Quality Control, Semen Analysis | NRF | 2 | 864.8625 |
| QwikCheck Dilution Kit | Formulations, Balanced Salt Solutions | KIP | 1 | 864.2875 |
| QwikCheck Vitality Kit | Eosin Y | HYB | 1 | 864.1850 |
| MaleMan Semen Transport Kit; Semen Preservative (Pack of 50/5mL) Single Use Vials for Semen Transportation/Preservation | Container, Specimen Mailer and Storage, Sterile | KDT | 1 | 864.3250 |
- CLIA Classifications: Certain compact models within the product pipeline maintain a CLIA-waived certification framework, allowing execution in localized point-of-care environments without requiring full, high-complexity laboratory infrastructure.[11][23]
Economic Impact
A 2022 decision-analytic model published in Urology observed that widespread deployment of at-home semen analysis serves as a cost-effective method for early oligospermia detection, accelerating the time to formal clinical evaluation with an andrology specialist while reducing patient anxiety and laboratory costs.[41]
References
- ↑ 1.0 1.1 1.2 1.3 Finelli, Renata; Leisegang, Kristian; Tumallapalli, Samhita; Henkel, Ralf; Agarwal, Ashok (July 2021). "The validity and reliability of computer-aided semen analyzers in performing semen analysis: a systematic review". Translational Andrology and Urology. 10 (7): 3120–3132. doi:10.21037/tau-21-34. PMC 8350227 Check
|pmc=value (help). PMID 34430412 Check|pmid=value (help). - ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 "Our History". Medical Electronic Systems. Retrieved 2026-06-01.
- ↑ 3.0 3.1 3.2 3.3 3.4 Coldewey, Devin (3 April 2017). "At-home sperm health selfies are on the rise". TechCrunch. Retrieved 2026-06-01.
- ↑ 4.0 4.1 4.2 "510(k) Premarket Notification K161493: YO Home Sperm Test" (PDF). U.S. Food and Drug Administration. Retrieved 2026-06-01.
- ↑ 5.0 5.1 5.2 "At Home Sperm Testing: Should You Do it Early in the Course of Trying to Get Pregnant?". Yale Medicine. Yale School of Medicine. Retrieved 2026-06-01.
- ↑ 6.0 6.1 6.2 "YO Home Sperm Test Found To Be A User-Friendly, Accurate Way to Screen Samples at Home". Cleveland Clinic Consult QD. Cleveland Clinic. Retrieved 2026-06-01.
- ↑ 7.0 7.1 7.2 "Femasys Partners with Medical Electronic Systems to Launch FemSperm Analysis Kit for use with FemaSeed". Globe Newswire. 22 September 2025. Retrieved 2026-06-01.
- ↑ 8.0 8.1 "510(k) Premarket Notification K220828: SQA-iO Sperm Quality Analyzer" (PDF). U.S. Food and Drug Administration. 7 August 2023. Retrieved 2026-06-01.
- ↑ 9.0 9.1 "510(k) Premarket Notification K241628: YO Home Sperm Test" (PDF). U.S. Food and Drug Administration. 29 November 2024. Retrieved 2026-06-01.
- ↑ 10.0 10.1 10.2 10.3 Agarwal, Ashok; Sharma, Rakesh K. (January 2007). "Automation is the key to standardized semen analysis using the automated SQA-V sperm quality analyzer". Fertility and Sterility. 87 (1): 156–162. doi:10.1016/j.fertnstert.2006.05.083. PMID 17081537.
- ↑ 11.0 11.1 11.2 11.3 Gonzalez, Daniel C.; Narasimman, Manish; Best, Jordan C.; Ory, Jesse; Ramasamy, Ranjith (October 2021). "Clinical Update on Home Testing for Male Fertility". The World Journal of Men's Health. 39 (4): 615–625. doi:10.5534/wjmh.200130. PMC 8443999 Check
|pmc=value (help). PMID 33474845 Check|pmid=value (help). - ↑ 12.0 12.1 Process Improvement Through Automated Semen Analysis. American Association of Clinical Chemistry Annual Meeting. Overlook Medical Center, Atlantic Health System. 2011.
- ↑ 13.0 13.1 Lammers, J.; Splingart, C.; Barriere, P.; Freour, T. (January 2014). "Double-blind prospective study comparing two automated sperm analyzers versus manual semen assessment". Journal of Assisted Reproduction and Genetics. 31 (1): 35–43. doi:10.1007/s10815-013-0139-2. PMID 24234418.
- ↑ 14.0 14.1 Hirano, Yuki; Shibahara, Hiroaki; Shimada, Kazuhiko; Yamanaka, Seiji; Suzuki, Tatsuya; Takamizawa, Satoru; Motoyama, Mitsuhiro; Suzuki, Mitsuaki (December 2003). "Accuracy of sperm velocity assessment using the Sperm Quality Analyzer V". Reproductive Medicine and Biology. 2 (4): 151–157. doi:10.1111/j.1447-0578.2003.00039.x. PMC 5907002. PMID 29699178.
- ↑ Said, T.M.; Sharma, R.K.; Agarwal, A. (2005). Evaluation of Automated Sperm Concentration Assessment Using SQA-V Sperm Quality Analyzer. ASRM Annual Meeting. Cleveland Clinic Foundation.
- ↑ Sharma, R.K.; Said, T.M.; Agarwal, A. (2005). Comparison of Sperm Motility Measurement Using SQA-V Automated Sperm Analyzer and Conventional Manual Methods. ASRM Annual Meeting. Cleveland Clinic Foundation.
- ↑ Rabinovitch, L.; Greenberg, S. (2005). Automated Semen Analysis. American Association of Clinical Chemistry Annual Meeting.
- ↑ IVF Australia (August 2015). QAP semen analysis results using the SQA-V GOLD in compliance with ISO15189 (Report).
- ↑ Ilardo, Claudio; Defort, Naomi; Gala, Anna; Ostengo, Violaine; Vigouroux, Gilles Regnier; Quere, Guillaune; Sanguinet, Pierre (August 2024). "Retrospective study investigating the performance of the SQA-vision analyser compared with manual semen analysis". Scandinavian Journal of Clinical and Laboratory Investigation. doi:10.1080/00365513.2024.2392245. PMID 39146445 Check
|pmid=value (help). - ↑ Chtourou, S.; Reignier, A.; Lammers, J.; Splingart, C.; Barriere, P.; Freour, T. (2018). Is it time to switch to automated semen analysis? A comparative double-blind study between 2 recent sperm analyzers and manual semen analysis. ESHRE Annual Meeting.
- ↑ Allen, Emily; Le, Samantha; Cooke, Simon (2015). Automated Semen Analysis: The end of Manual Analysis?. IVF Australia Annual Meeting.
- ↑ "510(k) Premarket Notification K243114: SQA-iOw Sperm Quality Analyzer" (PDF). U.S. Food and Drug Administration. Retrieved 2026-06-01.
- ↑ 23.0 23.1 Bar-Chama, Natan; Rabinovitch, Lev (2024). Precision and Accuracy of the SQA-iOw Sperm Quality Analyzer in the Hands of CLIA Waived RN Operators. ASRM Scientific Congress and Expo. Denver, CO.
- ↑ Johnston, R.C.; Clarke, G.N.; Liu, D.Y.; Baker, H.W. (May 1995). "Assessment of the Sperm Quality Analyzer". Fertility and Sterility. 63 (5): 1071–1076. doi:10.1016/S0015-0282(16)57564-7. PMID 7720920.
- ↑ Mahmoud, A.M.; Gordts, S.; Vereecken, A.; Serneels, A.; Campo, R.; Rombauts, L.; Comhaire, F.H. (February 1998). "Performance of the sperm quality analyser in predicting the outcome of assisted reproduction". International Journal of Andrology. 21 (1): 41–46. doi:10.1046/j.1365-2605.1998.00090.x. PMID 9639151.
- ↑ Shibahara, H.; Naito, S.; Hasegawa, A.; Mitsuo, M.; Shigeta, M.; Koyama, K. (April 1997). "Evaluation of sperm fertilizing ability using the Sperm Quality Analyzer". International Journal of Andrology. 20 (2): 112–117. doi:10.1046/j.1365-2605.1997.00035.x. PMID 9292322.
- ↑ Kazama, T.; Ohta, S.; Iwasaki, M.; Fuse, H. (1998). "Evaluation of Sperm Quality Analyzer". Japanese Journal of Fertility and Sterility. 43 (1): 17–21.
- ↑ Fuse, H.; Akashi, T.; Nozaki, T.; Nishio, R.; Mizuno, I. (January 2005). "Assessment of sperm quality analyzer II B: comparison with manual semen analysis and CASA". Archives of Andrology. 51 (1): 65–67. doi:10.1080/014850190512331. PMID 15764419.
- ↑ Suzuki, T.; Shibahara, H.; Tsunoda, H.; Hirano, Y.; Taneichi, A.; Obara, H.; Takamizawa, S.; Sato, I. (February 2002). "Comparison of the Sperm Quality Analyzer IIC variables with the computer-aided sperm analysis estimates". International Journal of Andrology. 25 (1): 49–54. doi:10.1046/j.1365-2605.2002.00325.x. PMID 11869377.
- ↑ Komori, S.; Hamada, Y.; Hasegawa, A.; Tsubamoto, H.; Horiuchi, I.; Tanaka, H.; Kasumi, H.; Shigeta, M.; Koyama, K. (2003). "A digital method of sperm immobilization test: comparison to the conventional method". American Journal of Reproductive Immunology. 50 (6): 481–484. doi:10.1046/j.8755-8920.2003.00108.x. PMID 14738300.
- ↑ 31.0 31.1 31.2 Bar-Chama, Natan; Rabinovitch, Lev; Honig, Stanton (August 2024). "Amateur vs Professional Users of the YO Home Sperm Test: An Assessment of Usability". Urology. 190: 162–169. doi:10.1016/j.urology.2024.04.001. PMID 38705243 Check
|pmid=value (help). - ↑ 32.0 32.1 32.2 32.3 Bar-Chama, Natan; Rabinovitch, Lev (2024). Accuracy and Usability of the YO (3.0) Home Sperm Test. ASRM Scientific Congress and Expo. Denver, CO.
- ↑ Parker, H.M.; McDaniel, C.D. (2004). "The Optimum Semen Dilution for the Sperm Quality Index that is Most Predictive of Broiler Breeder Fertility". International Journal of Poultry Science. 3 (9): 588–592.
- ↑ Parker, H.M.; McDaniel, C.D. (2002). "Selection of Young Broiler Breeders for Semen Quality Improves Hatchability in an Industry Field Trial". Journal of Applied Poultry Research. 11: 250–259.
- ↑ Neuman, S.L.; McDaniel, C.D.; Frank, L.; Radu, J.; Einstein, M.E.; Hester, P.Y. (July 2002). "Utilisation of a sperm quality analyser to evaluate sperm quantity and quality of turkey breeders". British Poultry Science. 43 (3): 457–464. doi:10.1080/00071660120103692. PMID 12195806.
- ↑ Neuman, S.L.; McDaniel, C.D.; Frank, L.; Radu, J.; Hester, P.Y. (July 2002). "Use of a sperm quality analyser on semen of turkey breeders to monitor storage time effects and age-related changes during a reproductive cycle". British Poultry Science. 43 (3): 465–471. doi:10.1080/00071660120103700. PMID 12195807.
- ↑ Karaca, A.G.; Parker, H.M.; McDaniel, C.D. (2002). "Elevated Body Temperature Directly Contributes to Heat Stress Infertility of Broiler Breeder Males". Poultry Science. 81: 1892–1897. doi:10.1093/ps/81.12.1892.
- ↑ Hoflack, G.; Rijsselaere, T.; Maes, D.; Dewulf, J.; Opsomer, G.; de Kruif, A.; Van Soom, A. (June 2005). "Validation and usefulness of the Sperm Quality Analyzer (SQA IL-C) for bull semen analysis". Reproduction in Domestic Animals. 40 (3): 237–244. doi:10.1111/j.1439-0531.2005.00582.x. PMID 15943698.
- ↑ Vyt, P.; Maes, D.; Rijsselaere, T.; Dejonckheere, E.; Castryck, F.; Van Soom, A. (December 2004). "Motility assessment of porcine spermatozoa: a comparison of methods". Reproduction in Domestic Animals. 39 (6): 447–453. doi:10.1111/j.1439-0531.2004.00531.x.
- ↑ 40.0 40.1 Ayyar, Archana; Khalil, Marian; Wong, Maggie; Chung, Rebecca; Coyne, Kathryn; Findley, Joseph; Weinerman, Rachel; Flyckt, Rebecca; Sofaly, Katelyn Perroz; Kim, Sung Tae (July 2025). "Improvement in Sperm Recovery Rate and Total Motile Sperm Count Using α-Chymotrypsin in Highly Viscous Semen Sample Without Adversely Affecting Assisted Reproductive Technology Outcomes". Reproductive Medicine. 6 (3). doi:10.3390/reprodmed6030017. Unknown parameter
|article-number=ignored (help) - ↑ Lai, Jeremy D.; Fantus, Richard J.; Meza, Julio A.; Hudnall, Matthew T.; Pham, Minh; Brannigan, Robert E.; Ghomrawi, Hassan M. K.; Halpern, Joshua A. (December 2022). "Cost-effectiveness of Early Screening Home Semen Analysis in Couples Attempting to Conceive". Urology. 170: 104–110. doi:10.1016/j.urology.2022.06.053. PMID 36115433 Check
|pmid=value (help).
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