NiTi Brush
Comment: Sources that only briefly mention the brush are not useful. S0091 (talk) 16:41, 6 October 2026 (UTC)
- Comment: Note that user has declared COI with the manufacturer of this product on their userpage grapesurgeon (talk) 02:53, 30 September 2026 (UTC)
Template:Infobox medical device
The NiTi Brush is a single-use rotary dental instrument with nickel-titanium bristles, manufactured by HANS KOREA CO.,Ltd. of Paju, South Korea. It is used for the mechanical debridement of the exposed surface of a dental implant during the surgical treatment of peri-implantitis.[1][2] In the dental literature it is one of several instruments described generically as a "titanium brush"; trial reports identify it, for example, as "a rotating titanium brush (Nano NiTi Brush, HANS KOREA CO. Ltd)".[1][3]
Design
The bristles are made of nickel-titanium, a shape-memory alloy, mounted on a shaft that fits a 20:1 reduction contra-angle handpiece driven by an implant motor.[2] The manufacturer supplies four head geometries, designated NANO, POCKET, POCKET SHORT and OMEGA, and specifies operation at 600–1,200 rpm under sterile saline irrigation. The instrument is supplied non-sterile and is intended for single use.[2] According to the manufacturer's instructions for use, the intended purpose is the mechanical decontamination and cleaning of the implant surface and the removal of granulation tissue from the implant surface and surrounding tissue.[2][4][5]
Clinical use
In published surgical protocols the brush is used after a full-thickness flap has been raised and granulation tissue removed, to instrument the exposed implant threads before the bony defect is grafted or the flap is closed.[1][6][7] In the reported randomised trials the brush was the mechanical decontamination step common to all treatment arms; the trials compared other measures, such as bone substitute materials, barrier membranes or adjunctive surface treatments, rather than decontamination instruments.[1][8][6][4][9][10][11]
A multicentre randomised controlled trial in Sweden and Spain treated 138 patients (147 implants) with reconstructive surgery in which the implant surface was instrumented with the NiTi Brush at up to 1,200 rpm under saline irrigation; a three-year follow-up of the same cohort was published in 2025.[1][8] Randomised trials from Barcelona and Bilbao used the instrument in the same role while comparing barrier membranes,[6][4] chemical and electrolytic surface adjuncts,[9][12][10] and the extent of implantoplasty.[11] A Swedish randomised trial comparing diode laser treatment with mucosal flap surgery used the instrument in the surgical arm.[13] Retrospective and case-series reports have described its use in combined resective–reconstructive protocols,[5][14][15][7] in the reconstructive treatment of advanced defects with a growth factor,[16] in the management of early implant complications,[17] and in a ten-year follow-up of a regeneratively treated case.[18]
Research
Laboratory studies have used the instrument to debride titanium discs or implant surfaces for comparison with other decontamination methods. An in vitro study reported that discs instrumented with the NiTi Brush and stored in saline showed higher cell viability at seven days than discs treated with a diamond polishing brush or a chemical gel, and that instrumentation time was shorter than with the polishing brush.[19] A study comparing eight debridement techniques on three titanium surfaces included the brush among the tested instruments,[20] and another measured the quantity and size of titanium particles released by different mechanical decontamination procedures, including the brush.[21] Further in vitro work has used the brush to debride bacterially colonised titanium discs before studying the immune response on the surface,[22] and to prepare zirconia hybrid implant surfaces for cell-culture experiments.[23] A 2025 study of peri-implant soft tissue found titanium micro-particles to be a common finding around dental implants and did not find an association with the occurrence of peri-implantitis.[24] A 2020 pilot study assessed volumetric soft-tissue changes after combined surgical therapy in which the surface was instrumented with the brush.[25]
The instrument has been discussed in a 2025 systematic review of chitosan and titanium brushes for peri-implant disease[3] and in a 2018 Japanese review of implant treatment safety.[26]
Regulatory status
The NiTi Brush is CE-marked as a medical device and is distributed through authorised distributors in a number of countries.[2]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Derks, J.; Ortiz-Vigón, A.; Guerrero, A. (2022). "Reconstructive surgical therapy of peri-implantitis: a multicenter randomized controlled clinical trial". Clinical Oral Implants Research. 33 (9): 921–944. doi:10.1111/clr.13972. PMC 9544523 Check
|pmc=value (help). PMID 35804491 Check|pmid=value (help). - ↑ 2.0 2.1 2.2 2.3 2.4 "NiTi Brush – Instructions for Use". HANS KOREA CO.,Ltd. Retrieved 30 September 2026.
- ↑ 3.0 3.1 Pappolla Sessa, C.; Pappolla Sessa, A.; Martín-Vacas, A. (2025). "Mucositis and peri-implant disease treatment with chitosan and titanium brushes: a systematic review". Journal of Clinical Medicine. 14 (23): 8306. doi:10.3390/jcm14238306. PMC 12692939 Check
|pmc=value (help). PMID 41375609 Check|pmid=value (help). - ↑ 4.0 4.1 4.2 Monje, A.; Pons, R.; Vilarrasa, J. (2023). "Significance of barrier membrane on the reconstructive therapy of peri-implantitis: a randomized controlled trial". Journal of Periodontology. 94 (3): 323–335. doi:10.1002/JPER.22-0511. PMID 36399349 Check
|pmid=value (help). - ↑ 5.0 5.1 Monje, A.; Pons, R.; Amerio, E. (2021). "Resolution of peri-implantitis by means of implantoplasty as adjunct to surgical therapy: a retrospective study". Journal of Periodontology. 93 (1): 110–122. doi:10.1002/JPER.21-0103. PMID 33904175 Check
|pmid=value (help). - ↑ 6.0 6.1 6.2 Regidor, E.; Ortiz-Vigón, A.; Romandini, M. (2023). "The adjunctive effect of a resorbable membrane to a xenogeneic bone replacement graft in the reconstructive surgical therapy of peri-implantitis: a randomized clinical trial". Journal of Clinical Periodontology. 50 (6): 765–783. doi:10.1111/jcpe.13796. PMID 36802084 Check
|pmid=value (help). - ↑ 7.0 7.1 Zhou, W.; Ramanauskaite, A.; Raabe, C. (2026). "Treatment outcome of surgical protocols for peri-implantitis: a retrospective cohort study in a specialised university centre". Journal of Clinical Periodontology. 53 (5): 658–680. doi:10.1111/jcpe.70115. PMC 13086545 Check
|pmc=value (help). PMID 41834225 Check|pmid=value (help). - ↑ 8.0 8.1 Alibegovic, L.; Trullenque-Eriksson, A.; Ortiz-Vigón, A. (2025). "Bone substitute material in the surgical therapy of peri-implantitis: 3-year outcomes of a randomized controlled trial". Clinical Oral Implants Research. 36 (4): 436–448. doi:10.1111/clr.14393. PMC 11996734 Check
|pmc=value (help). PMID 39704200 Check|pmid=value (help). - ↑ 9.0 9.1 Monje, A.; Navarro-Mesa, S.; Soldini, C. (2025). "Surface decontamination on the reconstructive therapy of peri-implantitis: a multicenter randomized clinical trial". Clinical Implant Dentistry and Related Research. 27 (4). doi:10.1111/cid.70075. PMC 12281608 Check
|pmc=value (help). PMID 40693504 Check|pmid=value (help). Unknown parameter|article-number=ignored (help) - ↑ 10.0 10.1 Regidor, E.; Ortiz-Vigón, A.; Berglundh-Gottlieb, J. (2026). "Adjunctive electrolytic implant surface decontamination in the reconstructive surgical treatment of peri-implantitis — a randomized clinical trial". Clinical Oral Implants Research. 37 (9): 1109–1117. doi:10.1111/clr.70152. PMC 13542734 Check
|pmc=value (help). PMID 42365519 Check|pmid=value (help). - ↑ 11.0 11.1 Monje, A.; Pons, R.; Aparicio, C. (2026). "Extent of implantoplasty in the combined surgical therapy of peri-implantitis: a quasi-randomized clinical trial". Clinical Implant Dentistry and Related Research. 28 (2). doi:10.1111/cid.70144. PMC 13107093 Check
|pmc=value (help). PMID 42026938 Check|pmid=value (help). Unknown parameter|article-number=ignored (help) - ↑ Monje, A.; Pons, R.; Peña, P. (2024). "Electrolytic surface decontamination in the reconstructive therapy of peri-implantitis: single-center outcomes of a randomized controlled trial". International Journal of Periodontics & Restorative Dentistry. 45 (2): 1–23. doi:10.11607/prd.7151. PMID 38820275 Check
|pmid=value (help). - ↑ Malmqvist, S.; Qadri, T.; Lira-Junior, R. (2025). "Treatment of peri-implantitis with diode laser or mucosal flap surgery: A clinical randomized controlled trial". Journal of Periodontology. 96 (10): 1126–1137. doi:10.1002/jper.24-0683. PMC 12572678 Check
|pmc=value (help). PMID 40125562 Check|pmid=value (help). - ↑ Schwarz, F.; Becker, K.; Albrecht, C. (2023). "Effectiveness of modified and control protocols for the surgical therapy of combined peri-implantitis-related defects: a retrospective analysis". Clinical Oral Implants Research. 34 (5): 512–520. doi:10.1111/clr.14057. PMID 36852537 Check
|pmid=value (help). - ↑ Brincat, A.; Antezack, A.; Sadowski, C. (2023). "Absence of progressive bone loss following peri-implantitis surgical therapy with implantoplasty: a case series". Applied Sciences. 13 (12): 7224. doi:10.3390/app13127224.
- ↑ Monje, A.; Pons, R.; Barootchi, S. (2025). "Recombinant human platelet-derived growth factor-BB–mediated reconstructive therapy of advanced peri-implantitis bone defects: a case series". International Journal of Oral Implantology. 18 (1): 47–57. PMID 40047362 Check
|pmid=value (help). - ↑ Babgi, W.; Felemban, B. (2024). "Management of early dental implant complication: a report of two cases". Journal of Umm Al-Qura University for Medical Sciences. 10: 114–121. doi:10.54940/ms75920247.
- ↑ Parma-Benfenati, S.; Roncati, M.; Parma-Benfenati, L.; Nava, P. (2026). "Bone stability after regenerative peri-implantitis treatment: a 10-year follow-up case study". Clinical Advances in Periodontics. 16 (3): 477–484. doi:10.1002/cap.10359. PMC 13603044 Check
|pmc=value (help). PMID 42415625 Check|pmid=value (help). - ↑ Brunello, G.; Becker, K.; Rauch, N. (2025). "The effect of NiTi brush, polishing brush, and chemical agent on the dental implant surface morphology and cytocompatibility". Clinical Implant Dentistry and Related Research. 27 (1). doi:10.1111/cid.13417. PMC 11798888 Check
|pmc=value (help). PMID 39569703 Check|pmid=value (help). Unknown parameter|article-number=ignored (help) - ↑ Tran, C.; Khan, A.; Meredith, N.; Walsh, L. J. (2023). "Influence of eight debridement techniques on three different titanium surfaces: a laboratory study". International Journal of Dental Hygiene. 21 (1): 238–250. doi:10.1111/idh.12616. PMC 10087144 Check
|pmc=value (help). PMID 35943293 Check|pmid=value (help). - ↑ Kao, A.; Tawse-Smith, A.; Ma, S. (2024). "Quantity and size of titanium particles released from different mechanical decontamination procedures on titanium discs: an in vitro study". Dentistry Journal. 12 (5): 123. doi:10.3390/dj12050123. PMC 11119952 Check
|pmc=value (help). PMID 38786521 Check|pmid=value (help). - ↑ Liu, X.; Deng, S.; Xie, J. (2023). "2-DG regulates immune imbalance on the titanium surface after debridement". International Journal of Molecular Sciences. 24 (14). doi:10.3390/ijms241411431. PMC 10380309 Check
|pmc=value (help). PMID 37511190 Check|pmid=value (help). Unknown parameter|article-number=ignored (help) - ↑ Tagliaferri, N.; Pisciotta, A.; Orlandi, G. (2024). "Zirconia hybrid dental implants influence the biological properties of neural crest-derived mesenchymal stromal cells". Nanomaterials. 14 (5): 392. doi:10.3390/nano14050392. PMC 10934982 Check
|pmc=value (help). PMID 38470723 Check|pmid=value (help). - ↑ Dionigi, C.; Nagy, G.; Derks, J. (2025). "Titanium micro-particles are commonly found in soft tissues surrounding dental implants". Communications Medicine. 5 (1). doi:10.1038/s43856-025-00756-3. PMC 11920262 Check
|pmc=value (help). PMID 40102654 Check|pmid=value (help). Unknown parameter|article-number=ignored (help) - ↑ Galarraga-Vinueza, M. E.; Obreja, K.; Magini, R. (2020). "Volumetric assessment of tissue changes following combined surgical therapy of peri-implantitis: a pilot study". Journal of Clinical Periodontology. 47 (9): 1159–1168. doi:10.1111/jcpe.13335. PMID 32585744 Check
|pmid=value (help). - ↑ Hiroyasu, K. (2018). 安心・安全なインプラント治療を行うために [Toward safe and secure implant treatment]. Journal of the Japanese Society of Oral Examination (in 日本語). 10 (1): 33–38.
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