PanTum Detect
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PanTum Detect is a blood test for the early detection of cancer. It is based on EDIM (Epitope Detection in Monocytes) technology and has been developed to provide indications for the presence of a tumor disease by detecting the markers TKTL1 and DNaseX (Apo10) in the blood. In case of an abnormal result, clarification by imaging procedures (PET/CT and MRI) is recommended.
The test was used at the University Medical Center Hamburg Eppendorf in a prospective multicenter study evaluating combined cancer screening by PanTum Detect and MRI/PET-CT to identify individuals from an asymptomatic group of subjects (over 5,000 50- to 70-year-olds) who are likely to benefit from further imaging.[1][2]
PanTum Detect officially received its market approval in 2017, and has been part of HanseMerkur health insurance's KrebsScan early detection program since September 2022.
Studies[edit]
- Epitope Detection in Monocytes (EDIM) As a New Method of Liquid Biopsy in Pediatric Rhabdomyosarcoma[3]
- Epitope detection in monocytes (EDIM) for liquid biopsy including identification of GD2 in childhood neuroblastoma—a pilot study[4]
References[edit]
- ↑ Simon Burg, Audrey Laure Céline Grust, Oliver Feyen, Katja Failing, Gamal-André Banat, Johannes F Coy, Martin Grimm, Martin Gosau, Ralf Smeets. "Blood-Test Based Targeted Visualization Enables Early Detection of Premalignant and Malignant Tumors in Asymptomatic Individuals".CS1 maint: Uses authors parameter (link)
- ↑ "Blood-Test Based Targeted Visualization Enables Early Detection of Premalignant and Malignant Tumors in Asymptomatic Individuals". Journal of Clinical and Medical Images. 6 (9): 1–12. May 2022.
- ↑ Urla, Cristian; Stagno, Matias Julian; Schmidt, Andreas; Handgretinger, Rupert; Fuchs, Jörg; Warmann, Steven W.; Schmid, Evi (2022). "Epitope Detection in Monocytes (EDIM) As a New Method of Liquid Biopsy in Pediatric Rhabdomyosarcoma". Biomedicines. 10 (8): 1812. doi:10.3390/biomedicines10081812. ISSN 2227-9059. PMC 9404738 Check
|pmc=value (help). PMID 36009359 Check|pmid=value (help). - ↑ Stagno, Matias J.; Schmidt, Andreas; Bochem, Jonas; Urla, Cristian; Handgretinger, Rupert; Cabanillas Stanchi, Karin M.; Saup, Rafael; Queudeville, Manon; Fuchs, Jörg; Warmann, Steven W.; Schmid, Evi (2022). "Epitope detection in monocytes (EDIM) for liquid biopsy including identification of GD2 in childhood neuroblastoma—a pilot study". British Journal of Cancer. 127 (7): 1324–1331. doi:10.1038/s41416-022-01855-x. ISSN 1532-1827. PMC 9519569 Check
|pmc=value (help). PMID 35864157 Check|pmid=value (help).
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