Phoenix-Micron, Inc.
Phoenix-Micron Inc. is a company specializing in precision ophthalmic imaging of the retina, cornea, and external structures of the eye for in vivo small animal research. Based in Bend, Oregon, USA, the company was formed after spinning out[1] of Phoenix Technology Group, which was founded by Bert Massie, the original inventor of the MICRON technology. With more than 14 years of experience in innovating patented[2] small animal imaging technology, over 450 papers have been published incorporating data from the MICRON product line. Leading research institutions use the MICRON platform, including Weill Cornell Medical College,[3] Johns Hopkins University,[4] Institut de la Vision,[5] and University of Melbourne[6].
History
The MICRON technology was originally developed by Dr. Bert Massie at Phoenix Research Labs,[7] a company he founded in Pleasanton, CA, USA, in 2007. The company originally focused solely on imaging systems for ophthalmic researchers conducting in vivo studies of the eyes of small animals. Dr. Massie's invention allowed researchers to transition from ex vivo research to in vivo research, which was not only more humane, but introduced new opportunities to conduct longitudinal studies.
Dr. Massie created a second company, Phoenix Clinical, which encompassed the development of the Phoenix ICON retinal imaging platform. The ICON camera system,[8] unlike the MICRON, was designed to image the human retina, primarily for screening neonatal patients for retinopathy of prematurity (ROP). Phoenix Clinical was later merged with Phoenix Research Labs to form Phoenix Technology Group.
Phoenix-Micron Inc. was formed as a separate company in 2021, founded by former Phoenix Technology Group employees. Phoenix-Micron acquired the MICRON product line assets from Phoenix Technology Group in November 2021. The spin-out[1] was completed to increase focus on and innovation of products designed to serve the eye and eye-brain research community.
Phoenix Technology Group was then acquired by NeoLight,[9] which continues to offer the ICON camera.
Products
The MICRON product line offers an integrated multi-modality system with seven imaging modalities designed for small animal ophthalmic research, including fundus imaging, fluorescent imaging, optical coherence tomography (OCT[10]), and electroretinography (ERG[11]). The latest product, the 'MICRON 5[12]', includes interchangeable imaging sensors, software-controlled camera operation, expanded filter capabilities, and new depth of field adjustments. The MICRON 5 platform is compatible with prior MICRON IV generation imaging modalities.
Notable Achievements
The MICRON platform has been used in over 450 published studies and offers precision tools for imaging and data capture. The launch of the MICRON 5 imaging system represents some of the latest advancements in small animal ophthalmic imaging technology.
References
- ↑ 1.0 1.1 Team, Phoenix-Micron (2021-11-29). "Phoenix MICRON Spins out of Phoenix Technology Group to Better Serve Eye and Eye-Brain Researchers Globally". Phoenix-Micron. Retrieved 2023-11-23.
- ↑ US7993000B2, Massie, Norbert A., "Method and apparatus for imaging an eye of a small animal", issued 2011-08-09
- ↑ Chuang, Jen-Zen; Yang, Nan; Nakajima, Nobuyuki; Otsu, Wataru; Fu, Cheng; Yang, Howard Hua; Lee, Maxwell Ping; Akbar, Armaan Fazal; Badea, Tudor Constantin; Guo, Ziqi; Nuruzzaman, Afnan; Hsu, Kuo-Shun; Dunaief, Joshua L.; Sung, Ching-Hwa (2022-01-18). "Retinal pigment epithelium-specific CLIC4 mutant is a mouse model of dry age-related macular degeneration". Nature Communications. 13 (1): 374. Bibcode:2022NatCo..13..374C. doi:10.1038/s41467-021-27935-9. ISSN 2041-1723. PMC 8766482 Check
|pmc=value (help). PMID 35042858 Check|pmid=value (help). - ↑ Kimball, Elizabeth; Schaub, Julie; Quillen, Sarah; Keuthan, Casey; Pease, Mary Ellen; Korneva, Arina; Quigley, Harry (2021-02-02). "The role of aquaporin-4 in optic nerve head astrocytes in experimental glaucoma". PLOS ONE. 16 (2): e0244123. Bibcode:2021PLoSO..1644123K. doi:10.1371/journal.pone.0244123. ISSN 1932-6203. PMC 7853498 Check
|pmc=value (help). PMID 33529207 Check|pmid=value (help). - ↑ Cadoni, Sara; Demené, Charlie; Alcala, Ignacio; Provansal, Matthieu; Nguyen, Diep; Nelidova, Dasha; Labernède, Guillaume; Lubetzki, Jules; Goulet, Ruben; Burban, Emma; Dégardin, Julie; Simonutti, Manuel; Gauvain, Gregory; Arcizet, Fabrice; Marre, Olivier (2023-04-03). "Ectopic expression of a mechanosensitive channel confers spatiotemporal resolution to ultrasound stimulations of neurons for visual restoration". Nature Nanotechnology. 18 (6): 667–676. Bibcode:2023NatNa..18..667C. doi:10.1038/s41565-023-01359-6. ISSN 1748-3395. PMC 10275757 Check
|pmc=value (help). PMID 37012508 Check|pmid=value (help). - ↑ Vessey, Kirstan A; Jobling, Andrew I; Tran, Mai X.; Wang, Anna Y.; Greferath, Ursula; Fletcher, Erica L. (2022-10-03). "Treatments targeting autophagy ameliorate the age-related macular degeneration phenotype in mice lacking APOE (apolipoprotein E)". Autophagy. 18 (10): 2368–2384. doi:10.1080/15548627.2022.2034131. ISSN 1554-8627. PMC 9542759 Check
|pmc=value (help). PMID 35196199 Check|pmid=value (help). - ↑ "Phoenix Research Labs - Crunchbase Company Profile & Funding".
- ↑ "510(k) Premarket Notification". www.accessdata.fda.gov.
- ↑ "NeoLight Newborn Care". www.theneolight.com.
- ↑ "Image-guided OCT".
- ↑ "Focal ERG".
- ↑ "Phoenix Micron 5".
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