Physiological reserve
Physiological reserve, also known as functional reserve, functional capacity and multi-organ reserve,[1] is a theoretical concept, most notable in geriatrics and gerontology, that describes the ability of the human body to cope with and recover from stressors. Physiological reserve is thought to peak at around age 25, after which it may decline with age.[2][3] Individuals with lower physiological reserve may struggle to maintain homeostasis, and may be more susceptible to illness and/or injury.[1][4] On a single-system level, physiological reserve is known as organ reserve.[1]
Description
Physiological reserve can be thought of as the body's ability to recover from a stressful event, such as after strenuous exercise, trauma, illness or surgical procedures. The lower an individual's physiological reserve, the more likely they are to suffer adverse outcomes following a stressful event.[4] However, it is often clinically or physiologically very difficult to model or quantify the complex physiological interactions that occur in the face of a given stressor and during its aftermath, which makes the concept difficult to define.[1] Low physiological reserve can result in the conditions collectively known as frailty in older age.[1][3][4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Romero-Ortuño, Román; Martínez-Velilla, Nicolás; Sutton, Richard; Ungar, Andrea; Fedorowski, Artur; Galvin, Rose; Theou, Olga; Davies, Andrew; Reilly, Richard; Claassen, Jurgen; Kelly, Áine; Ivanov, Plamen (7 July 2021). "Network Physiology in Aging and Frailty: The Grand Challenge of Physiological Reserve in Older Adults". Frontiers in Network Physiology. 1. doi:10.3389/fnetp.2021.712430.
- ↑ "What is physiological reserve". Retrieved 15 November 2021.
- ↑ 3.0 3.1 "Measuring The Physiological Reserve". Retrieved 15 November 2021.
- ↑ 4.0 4.1 4.2 McDermid, Robert; Bagshaw, Sean (July 2014). Stevens, Robert; Hart, Nicholas; Herridge, Margaret, eds. "Textbook of Post-ICU Medicine: The Legacy of Critical Care". Oxford University Press (published May 2014). Physiological Reserve and Frailty in Critical Illness. doi:10.1093/med/9780199653461.003.0028. ISBN 9780199653461. Retrieved 15 November 2021.
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