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Proteintech

From EverybodyWiki Bios & Wiki



Proteintech
Privately held company
ISIN🆔
IndustryLife Science
Founded 📆2001
Founder 👔
Headquarters 🏙️Chicago, Illinois
Area served 🗺️
Products 📟 Antibodies, ELISA Kits, IHC Kits, cytokines, growth factors, nanobodies
Members
Number of employees
🌐 Websitewww.ptglab.com
📇 Address
📞 telephone

Proteintech is a privately held company based in Chicago, Illinois that manufactures and sells antibodies, immunoassays, growth factors, cytokines, nanobodies and other related reagents. With the largest proprietary portfolio of self-manufactured antibodies covering two-thirds of the human proteome.[1][2][3], the company's products cover various research area such as neuroscience[4][5][6][7], cancer[8][9][10][11], immunology[12][13][14][15], epigentetics[16][17][18] and others. These products can be found cited in notable scientific peer-reviewed journals such as Nature, Cell, Science and more.

Based on the recent Top Antibodies in Research: 100 most cited products, 2025[19] report by CiteAb, Proteintech is the fifth most ranked supplier with 5% products in the 100.

In addition to research-use only reagents, Proteintech's human cell-expressed cytokines and growth factors are GMP-compliant for use in clinical trials and commercial manufacturing after obtaining their ISO 13485 certification in June 2020[20]

History

Proteintech was founded in 2001 by a group of scientists, including current CEO, Dr. Jason Li, who was an Associate Professor of Immunology at the University of Illinois at Chicago during the company's foundation years.[2][21]

Subsidiary

  • Proteintech Genomics - A provider of multiomic solutions for single-cell and spatial analysis.[22]

Acquisition

Awards

  • 2016 - CiteAb's Most Exciting Antibody Validation initiative[28]
  • 2019 - CiteAb's Rising Star in Immunology[29]
  • 2022 - CiteAb's Researchers' Choice[30]
  • 2022 - CiteAb's Environmental Initiative of the Year[31]
  • 2025 - CiteAb's Researchers' Choice[32]
  • 2025 - CiteAb's Educational Resource of the Year (Highly Commended)[33]

References

  1. ↑ "Proteintech Launches Able AI to Streamline Antibody Selection - SynBioBeta".
  2. ↑ 2.0 2.1 "Proteintech Group Celebrates 20-Year Anniversary" (Press release).
  3. ↑ "Chicago Inno - Biotech firm eyes IPO | Real estate startup acquired".
  4. ↑ Ma, X. R.; et al. (2022). "TDP-43 represses cryptic exon inclusion in the FTD–ALS gene UNC13A". Nature. 603 (7899): 124–130. Bibcode:2022Natur.603..124M. doi:10.1038/s41586-022-04424-7. PMC 8891019 Check |pmc= value (help). PMID 35197626 Check |pmid= value (help).
  5. ↑ Guo, L.; Mao, Q.; He, J.; Liu, X.; Piao, X.; Luo, L.; Hao, X.; Yu, H.; Song, Q.; Xiao, B.; Fan, D.; Gao, Z.; Jia, Y. (2023). "Disruption of ER ion homeostasis maintained by an ER anion channel CLCC1 contributes to ALS-like pathologies". Cell Research. 33 (7): 497–515. doi:10.1038/s41422-023-00798-z. PMC 10313822 Check |pmc= value (help). PMID 37142673 Check |pmid= value (help).
  6. ↑ Jinwal, U. K.; Miyata, Y.; Koren j, 3rd; Jones, J. R.; Trotter, J. H.; Chang, L.; O'Leary, J.; Morgan, D.; Lee, D. C.; Shults, C. L.; Rousaki, A.; Weeber, E. J.; Zuiderweg, E. R.; Gestwicki, J. E.; Dickey, C. A. (2009). "Chemical manipulation of hsp70 ATPase activity regulates tau stability". The Journal of Neuroscience : The Official Journal of the Society for Neuroscience. 29 (39): 12079–12088. doi:10.1523/JNEUROSCI.3345-09.2009. PMC 2775811. PMID 19793966.
  7. ↑ Jackson, K. L.; Dayton, R. D.; Klein, R. L. (2015). "AAV9 supports wide-scale transduction of the CNS and TDP-43 disease modeling in adult rats". Molecular Therapy. Methods & Clinical Development. 2. doi:10.1038/mtm.2015.36. PMC 4588447. PMID 26445725. Unknown parameter |article-number= ignored (help)
  8. ↑ Ren, X.; Huang, M.; Weng, W.; Xie, Y.; Wu, Y.; Zhu, S.; Zhang, Y.; Li, D.; Lai, J.; Shen, S.; Lin, J.; Kuang, M.; Li, X.; Yu, J.; Xu, L. (2023). "Personalized drug screening in patient-derived organoids of biliary tract cancer and its clinical application". Cell Reports. Medicine. 4 (11). doi:10.1016/j.xcrm.2023.101277. PMC 10694672 Check |pmc= value (help). PMID 37944531 Check |pmid= value (help). Unknown parameter |article-number= ignored (help)
  9. ↑ Wei, Wenxia; Qin, Baifu; Wen, Weijie; Zhang, Boyu; Luo, Haidan; Wang, Yuzhi; Xu, Hui; Xie, Xiaoshan; Liu, Sicheng; Jiang, Xin; Wang, Mengan; Tang, Qin; Zhang, Jiayu; Yang, Runxiang; Fan, Zongmin; Lyu, Haiwen; Lin, Junzhong; Li, Kai; Lee, Mong-Hong (2023). "FBXW7β loss-of-function enhances FASN-mediated lipogenesis and promotes colorectal cancer growth". Signal Transduction and Targeted Therapy. 8 (1). doi:10.1038/s41392-023-01405-8. PMC 10195794 Check |pmc= value (help). PMID 37202390 Check |pmid= value (help). Unknown parameter |article-number= ignored (help)
  10. ↑ Wang, Jin; Tan, Lirong; Yu, Xueting; Cao, Xiyuan; Jia, Beibei; Chen, Rui; Li, Jianxiang (2022). "LncRNA ZNRD1-AS1 promotes malignant lung cell proliferation, migration, and angiogenesis via the miR-942/TNS1 axis and is positively regulated by the m6A reader YTHDC2". Molecular Cancer. 21 (1). doi:10.1186/s12943-022-01705-7. PMC 9801573 Check |pmc= value (help). PMID 36581942 Check |pmid= value (help). Unknown parameter |article-number= ignored (help)
  11. ↑ https://academic.oup.com/proteincell/article/14/2/123/6709361
  12. ↑ Yazicioglu, Yavuz F.; Marin, Eros; Sandhu, Ciaran; Galiani, Silvia; Raza, Iwan G. A.; Ali, Mohammad; Kronsteiner, Barbara; Compeer, Ewoud B.; Attar, Moustafa; Dunachie, Susanna J.; Dustin, Michael L.; Clarke, Alexander J. (2023). "Dynamic mitochondrial transcription and translation in B cells control germinal center entry and lymphomagenesis". Nature Immunology. 24 (6): 991–1006. doi:10.1038/s41590-023-01484-3. PMC 10232359 Check |pmc= value (help). PMID 37095377 Check |pmid= value (help).
  13. ↑ Schmidt, N.; et al. (2023). "SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9". Cell. 186 (22): 4834–4850.e23. doi:10.1016/j.cell.2023.09.002. PMC 10617981 Check |pmc= value (help). PMID 37794589 Check |pmid= value (help).
  14. ↑ Travelli, Cristina; Colombo, Giorgia; Aliotta, Martina; Fagiani, Francesca; Fava, Natalia; De Sanctis, Rita; Grolla, Ambra A.; Garcia, Joe G N.; Clemente, Nausicaa; Portararo, Paola; Costanza, Massimo; Condorelli, Fabrizio; Colombo, Mario Paolo; Sangaletti, Sabina; Genazzani, Armando A. (2023). "Extracellular nicotinamide phosphoribosyltransferase (ENAMPT) neutralization counteracts T cell immune evasion in breast cancer". Journal for Immunotherapy of Cancer. 11 (10): e007010. doi:10.1136/jitc-2023-007010. PMC 10603332 Check |pmc= value (help). PMID 37880182 Check |pmid= value (help).
  15. ↑ Jeyanathan, Mangalakumari; Vaseghi-Shanjani, Maryam; Afkhami, Sam; Grondin, Jensine A.; Kang, Alisha; d'Agostino, Michael R.; Yao, Yushi; Jain, Shreya; Zganiacz, Anna; Kroezen, Zachary; Shanmuganathan, Meera; Singh, Ramandeep; Dvorkin-Gheva, Anna; Britz-Mckibbin, Philip; Khan, Waliul I.; Xing, Zhou (2022). "Parenteral BCG vaccine induces lung-resident memory macrophages and trained immunity via the gut–lung axis". Nature Immunology. 23 (12): 1687–1702. doi:10.1038/s41590-022-01354-4. PMID 36456739 Check |pmid= value (help).
  16. ↑ Zhou, Hong; Liu, Yujie; Tian, Geng G.; Wu, Ji (2025). "Nicotinamide mononucleotide promotes female germline stem cell proliferation by activating the H4K16ac-Hmgb1-Fyn-PLD signaling pathway through epigenetic remodeling". Cell & Bioscience. 15 (1). doi:10.1186/s13578-025-01387-w. PMC 12004683 Check |pmc= value (help). PMID 40247362 Check |pmid= value (help). Unknown parameter |article-number= ignored (help)
  17. ↑ Jin, Yu; Liu, Zhen; Li, Zhenxia; Li, Hairui; Zhu, Cheng; Li, Ruomei; Zhou, Ting; Fang, Bing (2022). "Histone demethylase JMJD3 downregulation protects against aberrant force-induced osteoarthritis through epigenetic control of NR4A1". International Journal of Oral Science. 14. doi:10.1038/s41368-022-00190-4. PMID 35831280 Check |pmid= value (help). Unknown parameter |article-number= ignored (help)
  18. ↑ Murase, Yusuke; Yokogawa, Ryuta; Yabuta, Yukihiro; Nagano, Masahiro; Katou, Yoshitaka; Mizuyama, Manami; Kitamura, Ayaka; Puangsricharoen, Pimpitcha; Yamashiro, Chika; Hu, Bo; Mizuta, Ken; Tsujimura, Taro; Yamamoto, Takuya; Ogata, Kosuke; Ishihama, Yasushi; Saitou, Mitinori (2024). "In vitro reconstitution of epigenetic reprogramming in the human germ line". Nature. 631 (8019): 170–178. Bibcode:2024Natur.631..170M. doi:10.1038/s41586-024-07526-6. PMC 11222161 Check |pmc= value (help). PMID 38768632 Check |pmid= value (help).
  19. ↑ "Top Antibodies in Research: 100 most cited products, 2025 update".
  20. ↑ "Proteintech announces ISO 13485 Certification for Its HumanKine® Human Cell-expressed Cytokines and Growth Factors". 4 June 2020.
  21. ↑ "Sponsor Information - Researcher Hub - University of Liverpool".
  22. ↑ "Proteintech Genomics Launches First Commercially Available Solution for the Detection of Intracellular Proteins for Single-Cell RNAseq Experiments".
  23. ↑ "Proteintech Group Acquires Manufacturer of Human Cell-Expressed Proteins, HumanZyme".
  24. ↑ "M&As this week: Wacker Biotech, Pacific Glory Development, Proteintech Group". 19 April 2018.
  25. ↑ "Proteintech Acquires ChromoTek, Expanding its Next Generation Antibody Tools" (Press release).
  26. ↑ https://www.invest-in-bavaria.com/en/blog/post/chicago-planegg-martinsried-us-amerikanische-proteintech-group-verdreifacht-groesse-des-standorts-in-bayern-fokus-auf-forschung-entwicklung-produktion-und-logistik
  27. ↑ "Proteintech Acquires ChromoTek, Expanding its Next Generation Antibody Tools". 21 October 2020.
  28. ↑ "CiteAb Awards 2016 - Most exciting antibody validation initiative".
  29. ↑ "Rising star in immunology - CiteAb Awards 2019".
  30. ↑ "Researchers' Choice - CiteAb Awards 2022".
  31. ↑ "Environmental Initiative of the Year - CiteAb Awards 2022".
  32. ↑ "Researchers' Choice - CiteAb Awards 2025".
  33. ↑ "Educational Resource of the Year - CiteAb Awards 2025".

External links


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