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Se-Jin Lee

From EverybodyWiki Bios & Wiki


Se-Jin Lee
Born(1958-10-20)October 20, 1958
Seoul, South Korea
🎓 Alma materHarvard University
💼 Occupation
Known formechanisms of controlled muscle hypertrophy utilizing myostatin
👩 Spouse(s)Emily Lucy Germain-Lee
👶 ChildrenBenjamin Charles Germain Lee
🏅 AwardsRolf Luft Award

Se-Jin Lee (October 20, 1958 – ) is an American biologist and professor at the University of Connecticut and at the Jackson Laboratory.

His work has had a wide impact on the understanding of how skeletal muscle mass is controlled. He discovered several proteins in the large "TGFbeta" family of cytokines, including myostatin, also known as "GDF8", Activin A, GDF11, etc.

Most of his work has employed the use of genetically modified mice. For example, mice that were made null for myostatin/GDF8 demonstrated almost a two-fold increase in skeletal muscle mass, which showed that myostatin is a natural inhibitor of muscle differentiation and growth.

References


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