Seth B. Herzon
Seth B. Herzon (b. 1980) is an American organic chemist and the Milton Harris ’29 Ph.D. Professor of Chemistry at Yale University.[1][2] Herzon's research focuses on the synthesis of complex natural products.
Early life and education
Herzon graduated from Valley Forge Military Academy, a private high school outside of Philadelphia, Pennsylvania. After briefly working in a pizzeria, Herzon enrolled at Temple University where his father was a professor of political science. While at Temple, Herzon worked in the lab of Grant Krow, an organic chemist.[3] Herzon completed a PhD in chemistry at Harvard University in 2006 under Andrew Myers and worked until 2008 as a postdoctoral scholar at University of Illinois, Urbana-Champaign.
Career and research
Herzon began his independent career at Yale University in 2008, and received tenure in 2013. He is currently the Milton Harris '29 Ph.D. Professor of Chemistry. His work is focused on the total synthesis of complex natural products, and he has achieved several landmark syntheses including hasubanonine,[4] kinamycin F,[5]huperzine A,[6] and pleuromutilin.[7]
Notes
References
- ↑ "Seth Herzon | Department of Chemistry". chem.yale.edu. 2026-02-15. Retrieved 2026-04-22.
- ↑ Tremblay, Jean-François (2025-01-21). "2014 Arthur C. Cope Early Career Scholars Award: Seth Herzon". Chemical & Engineering News. Retrieved 2026-04-22.
- ↑ Kosik, Eddy. "One Professor Changed His Life. Now This Owl Is Giving Back". temple-university-ia.shorthandstories.com. Retrieved 2026-04-22.
- ↑ Herzon 2011
- ↑ Woo 2010
- ↑ MK 2011
- ↑ Murphy 2017
- Herzon, Seth B.; Calandra, Nicholas A.; King, Sandra M.; McCarthy, M. C.; Gauss, J. (2011). "Efficient Entry to the Hasubanan Alkaloids: First Enantioselective Total Syntheses of (−)-Hasubanonine, (−)-Runanine, (−)-Delavayine, and (+)-Periglaucine B". Angewandte Chemie International Edition. 50 (38): 8863–8866. doi:10.1002/anie.201102226. PMID 21638524
- Woo, C. M.; Lu, L.; Gholap, S. L.; Smith, D. R.; Herzon, S. B. (2010). "Development of a Convergent Entry to the Diazofluorene Antitumor Antibiotics: Enantioselective Synthesis of Kinamycin F". Journal of the American Chemical Society. 132 (8): 2540–1. doi:10.1021/ja910769j. PMID 20141138.
- Moe Tun MK, Wüstmann DJ, Herzon SB (2011). "A robust and scalable synthesis of the potent neuroprotective agent (−)-huperzine A". Chemical Science. 2 (11): 2251–2253. doi:10.1039/C1SC00455G. S2CID 98224866
- Murphy SK, Zeng M, Herzon SB (June 2017). "A modular and enantioselective synthesis of the pleuromutilin antibiotics". Science. 356 (6341): 956–959. Bibcode:2017Sci...356..956M. doi:10.1126/science.aan0003
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