Steven E. Jacobsen

Steven Jacobsen's research endeavors revolve around unraveling the intricate processes of DNA methylation and epigenetic gene regulation, which hold pivotal significance in developmental processes, transposon defense, and maintaining genome integrity. Through their investigations conducted in both the model plant Arabidopsis and mouse models, Jacobsen and his team place their primary emphasis on deciphering the interplay among DNA methylation, histone methylation, and noncoding RNAs. These converging pathways intricately contribute to the stable and inheritable repression of gene transcription. Such insights into the molecular machinery governing gene activation and silencing have the potential to advance various fields, including the development of more effective cancer therapies.

He is a prestigious HHMI investigator.

References

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