Swayam Prakash
Comment: In accordance with Wikipedia's Conflict of interest guideline, I disclose that I have a conflict of interest regarding the subject of this article. Swayam.immunogenetics (talk) 06:45, 23 July 2026 (UTC)
Swayam Prakash
Swayam Prakash (born 1987) is an Indian immunogeneticist, and a scientist known for his works on vaccine development & research. He is currently working as a Assistant Research Professor at the University of California, Irvine.[1].
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Early life and education
Swayam Prakash was born in Bhubaneswar, Odisha, India. Swayam received a Master of Science degree from the Utkal University in Bhubaneswar. He received his Ph.D. degree after pursuing his research in the field of Histocompatibility and Transplantation Immunology from the Sanjay Gandhi Postgraduate Institute of Medical Sciences in Lucknow. As part of his training, from 2018 to 2023 Swayam completed a post-doctoral fellowship in Immunology at the Gavin Herbert Eye Institute at the University of California, Irvine School of Medicine. Prior to joining the University of California he served as a senior Research associate at the University Hospital Essen (Universitätsklinikum Essen).
Career
Swayam's career started at the University of California, Irvine School of Medicine as a Research Scientist in 2023 and subsequently as a Assistant Research Professor in 2024 at the Department of Ophthalmology.
Selected Research
His research from Sanjay Gandhi Postgraduate Institute of Medical Sciences examined the molecular profiling of killer immunoglobulin-like receptors and their HLA Class-I ligands in end stage renal disease[2][3][4]. His subsequent research focused on vaccine development and immunogenetics, particularly developing immunotherapeutic strategies against ocular and genital herpes simplex infection and SARS-CoV-2 infection [5]. At University of California, Irvine School of Medicine, he has led projects developing multi-epitope and large-sequence "Universal" Pan-Coronavirus vaccines [6] [7][8][9][10][11][12]. He has also contributed to identifying HLA-A*0201-restricted CD8+ cytotoxic T-lymphocyte epitopes from herpes simplex virus tegument proteins as foundations for a new class of human herpes vaccines[13][14][15]
Awards and Honors
Swayam is an elected Fellow of the Royal Society of Biology (FRSB) and has published 77 original research articles and review papers in the fields of vaccine development, and immunogenetics. His publications from the last decade have garnered over 54,000 citations with an h-index of 30 putting him among the highest cited researchers in the world. He has been awarded in 2025 with the prestigious 20/20 Society Grant.
References
- ↑ "Swayam Prakash". scholarconnect.uci.edu. Retrieved 2026-07-23.
- ↑ Prakash, Swayam; Alam, Shahnawaz; Sharma, Raj Kumar; Sonawane, Avinash; Imran, Mohd; Agrawal, Suraksha (2013-10). "Distribution of Killer cell immunoglobulin like receptor genes in end stage renal disease among North Indian population". Human Immunology. 74 (10): 1339–1345. doi:10.1016/j.humimm.2013.06.015. ISSN 1879-1166. PMID 23777934. Check date values in:
|date=(help) - ↑ Prakash, Swayam; Sarangi, Aditya Narayan; Alam, Shahnawaz; Sonawane, Avinash; Sharma, Raj Kumar; Agrawal, Suraksha (2017-12-30). "Putative role of KIR3DL1/3DS1 alleles and HLA-Bw4 ligands with end stage renal disease and long term renal allograft survival". Gene. 637: 219–229. doi:10.1016/j.gene.2017.09.033. ISSN 1879-0038. PMID 28942035.
- ↑ Prakash, Swayam; Alam, Shahnawaz; Faridi, Rehan Mujeeb; Sonawane, Avinash; Agrawal, Suraksha (2014). "Killer immunoglobulin like receptor gene content diversity among Northern Indian population". Annals of Human Biology. 41 (6): 540–547. doi:10.3109/03014460.2014.899624. ISSN 1464-5033. PMID 24689793.
- ↑ "UCI Scientists Developing More Effective Vaccine". NBC Los Angeles. Retrieved 2026-07-23.
- ↑ Irvine, Jo Kwon. "UC Irvine Researchers Working on a Vaccine for All Coronaviruses". spectrumnews1.com. Retrieved 2026-07-23.
- ↑ Prakash, Swayam; Srivastava, Ruchi; Coulon, Pierre-Gregoire; Dhanushkodi, Nisha R.; Chentoufi, Aziz A.; Tifrea, Delia F.; Edwards, Robert A.; Figueroa, Cesar J.; Schubl, Sebastian D.; Hsieh, Lanny; Buchmeier, Michael J.; Bouziane, Mohammed; Nesburn, Anthony B.; Kuppermann, Baruch D.; BenMohamed, Lbachir (2021-06-01). "Genome-Wide B Cell, CD4+, and CD8+ T Cell Epitopes That Are Highly Conserved between Human and Animal Coronaviruses, Identified from SARS-CoV-2 as Targets for Preemptive Pan-Coronavirus Vaccines". Journal of Immunology. 206 (11): 2566–2582. doi:10.4049/jimmunol.2001438. ISSN 1550-6606. PMC 8722450 Check
|pmc=value (help). PMID 33911008 Check|pmid=value (help). - ↑ Prakash, Swayam; Dhanushkodi, Nisha R.; Zayou, Latifa; Ibraim, Izabela Coimbra; Quadiri, Afshana; Coulon, Pierre Gregoire; Tifrea, Delia F.; Suzer, Berfin; Shaik, Amin Mohammed; Chilukuri, Amruth; Edwards, Robert A.; Singer, Mahmoud; Vahed, Hawa; Nesburn, Anthony B.; Kuppermann, Baruch D. (2024). "Cross-protection induced by highly conserved human B, CD4+, and CD8+ T-cell epitopes-based vaccine against severe infection, disease, and death caused by multiple SARS-CoV-2 variants of concern". Frontiers in Immunology. 15: 1328905. doi:10.3389/fimmu.2024.1328905. ISSN 1664-3224. PMC 10839970 Check
|pmc=value (help). PMID 38318166 Check|pmid=value (help). - ↑ Coulon, Pierre-Gregoire; Prakash, Swayam; Dhanushkodi, Nisha R.; Srivastava, Ruchi; Zayou, Latifa; Tifrea, Delia F.; Edwards, Robert A.; Figueroa, Cesar J.; Schubl, Sebastian D.; Hsieh, Lanny; Nesburn, Anthony B.; Kuppermann, Baruch D.; Bahraoui, Elmostafa; Vahed, Hawa; Gil, Daniel (2024). "High frequencies of alpha common cold coronavirus/SARS-CoV-2 cross-reactive functional CD4+ and CD8+ memory T cells are associated with protection from symptomatic and fatal SARS-CoV-2 infections in unvaccinated COVID-19 patients". Frontiers in Immunology. 15: 1343716. doi:10.3389/fimmu.2024.1343716. ISSN 1664-3224. PMC 11007208 Check
|pmc=value (help). PMID 38605956 Check|pmid=value (help). - ↑ Zayou, Latifa; Prakash, Swayam; Vahed, Hawa; Dhanushkodi, Nisha Rajeswari; Quadiri, Afshana; Belmouden, Ahmed; Lemkhente, Zohra; Chentoufi, Aziz; Gil, Daniel; Ulmer, Jeffrey B.; BenMohamed, Lbachir (2025). "Dynamics of spike-specific neutralizing antibodies across five-year emerging SARS-CoV-2 variants of concern reveal conserved epitopes that protect against severe COVID-19". Frontiers in Immunology. 16: 1503954. doi:10.3389/fimmu.2025.1503954. ISSN 1664-3224. PMC 11876060 Check
|pmc=value (help). PMID 40040708 Check|pmid=value (help). - ↑ Vahed, Hawa; Prakash, Swayam; Quadiri, Afshana; Ibraim, Izabela Coimbra; Omorogieva, Etinosa; Patel, Swena; Tadros, Jimmy; Liao, Emma Jane; Lau, Lauren; Chentoufi, Aziz A.; Nesburn, Anthony B.; Kuppermann, Baruch D.; Ulmer, Jeffrey B.; Gil, Daniel; BenMohamed, Lbachir (2025-12). "A pan-beta-coronavirus vaccine bearing conserved and asymptomatic B- and T-cell epitopes protects against highly pathogenic Delta and highly transmissible Omicron SARS-CoV-2 variants". Human Vaccines & Immunotherapeutics. 21 (1): 2527438. doi:10.1080/21645515.2025.2527438. ISSN 2164-554X. PMC 12233765 Check
|pmc=value (help). PMID 40613499 Check|pmid=value (help). Check date values in:|date=(help) - ↑ Prakash, Swayam; Dhanushkodi, Nisha R.; Quadiri, Afshana; Vahed, Hawa; Chentoufi, Aziz A.; Coulon, Pierre-Gregoire; Ibraim, Izabela Coimbra; Babsiri, Assia El; Tifrea, Delia F. (2025-08-20), A Multi-Antigen Broad-Spectrum Coronavirus Vaccine Induces Potent and Durable Cross-Protection Against Infection and Disease Caused by Multiple SARS-CoV-2 Variants, doi:10.21203/rs.3.rs-7208748/v1, PMC 12393516 Check
|pmc=value (help), PMID 40894020 Check|pmid=value (help), rs.3.rs-7208748, retrieved 2026-07-23 - ↑ Srivastava, Ruchi; Coulon, Pierre-Gregoire A.; Prakash, Swayam; Dhanushkodi, Nisha R.; Roy, Soumyabrata; Nguyen, Angela M.; Alomari, Nuha I.; Mai, Uyen T.; Amezquita, Cassendra; Ye, Caitlin; Maillère, Bernard; BenMohamed, Lbachir (2020-03-17). "Human Epitopes Identified from Herpes Simplex Virus Tegument Protein VP11/12 (UL46) Recall Multifunctional Effector Memory CD4+ TEM Cells in Asymptomatic Individuals and Protect from Ocular Herpes Infection and Disease in "Humanized" HLA-DR Transgenic Mice". Journal of Virology. 94 (7): e01991–19. doi:10.1128/JVI.01991-19. ISSN 1098-5514. PMC 7081904 Check
|pmc=value (help). PMID 31915285. - ↑ Prakash, Swayam; Roy, Soumyabrata; Srivastava, Ruchi; Coulon, Pierre-Gregoire; Dhanushkodi, Nisha R.; Vahed, Hawa; Jankeel, Allen; Geertsema, Roger; Amezquita, Cassandra; Nguyen, Lan; Messaoudi, Ilhem; Burkhardt, Amanda M.; BenMohamed, Lbachir (2020-08-14). "Unique molecular signatures of antiviral memory CD8+ T cells associated with asymptomatic recurrent ocular herpes". Scientific Reports. 10 (1): 13843. doi:10.1038/s41598-020-70673-z. ISSN 2045-2322. PMC 7427992 Check
|pmc=value (help). PMID 32796943 Check|pmid=value (help). - ↑ Dhanushkodi, Nisha R.; Srivastava, Ruchi; Coulon, Pierre-Gregoire A.; Prakash, Swayam; Roy, Soumyabrata; Bagnol, Didier; David, Eveleth D.; BenMohamed, Lbachir (2021). "Healing of Ocular Herpetic Disease Following Treatment With an Engineered FGF-1 Is Associated With Increased Corneal Anti-Inflammatory M2 Macrophages". Frontiers in Immunology. 12: 673763. doi:10.3389/fimmu.2021.673763. ISSN 1664-3224. PMC 8158292 Check
|pmc=value (help). PMID 34054858 Check|pmid=value (help).
References
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