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Walter Wahli

From EverybodyWiki Bios & Wiki



Walter Wahli
Born
🎓 Alma mater
💼 Occupation
🏅 Awards
  • Received Life Time Achievement Award[1]
🌐 Website
  • {{URL|example.com|optional display text}}

Prof. Walter Wahli is a Professor of Metabolic disease in Lee Kong Chian School of Medicine, a joint Medical School by Nanyang Technological University Singapore and Imperial College London.[2] He won the Lifetime Achievement Award from the faculty of Biology and Medicine, at the University of Lausanne.[3]

Education

Prof. Dr. Walter Wahli was born on 23rd May 1946 in Moutier, Switzerland. He studied Biological Sciences at the University of Bern in Switzerland; he earned his Ph.D. from the same university.[4]

Research and career

Prof. Dr. Walter Wahli's research mainly focuses on the Peroxisome proliferator-activated receptors (PPARs)[5] and he also did research on other nuclear receptors as positive and negative regulators of gene expression.[6] He investigated the role of PPARs in the most common liver disease known as Non-alcoholic fatty liver disease (NAFLD).[7] He underscored the potential of PPARs as drug targets for NAFLD that is often associated to Type 2 diabetes. Walter also did research on the PPARs as receptors exerting a nuclear control of energy metabolism.[8]

He is an Honorary Professor at the University of Lausanne (UNIL).[9] He is the Founder of the Center for Integrative Genomics (CIG) and currently serving at the Lee Kong Chian School of Medicine, a joint Medical School by Nanyang Technological University Singapore and Imperial College London as a Visiting Professor of Metabolic Disease.[10][11]

Prof. Dr. Walter Wahli obtained patents for his inventions. His patents include the Composition for regulating lipid metabolism (US8518459B2)[12] and the Composition for enhancing immunity (WO2014170505A3).[13]

Honors

Prof. Dr. Walter Wahli is one of the Advisory Board members of Imagene Labs, Singapore.[14] He served as a Scientific advisory board member of an International Cancer Prevention Institute.[15] He was a member of the Swiss National Science Foundation research council and presided over the Biology and Medicine Division.[16] His Editorial Memberships include, among others, the Open Nutrition Journal[17], Journal of Steroid Biochemistry and Molecular Biology[18] and Editorial board member of Cell & Bioscience.[19]

Dr. Walter Wahli won the Otto-Naegeli-Preis Award for his medical research in the field of Cell Biology/Energy homeostasis. Additional awards include the European Federation of Lipid research Award[20] and Lifetime Achievement Award from the University of Lausanne.[21] He was appointed as a Pierre De Fermat Chair of Excellence at Midi-Pyrenees research Centre, Toulouse.[22] He is a Guest Editor of International Journal of Molecular sciences.[23]

Publications

  • Walter Wahli and Liliane Michalik. "PPARs at the crossroads of lipid signaling and inflammation". Trends in Endocrinology & Metabolism.[24]
  • W Wahli and E Martinez. "Superfamily of steroid nuclear receptors: positive and negative regulators of gene expression". The FASEB Journal.[25]
  • W.Wahli, O.Braissant, and B.Desvergne. "Peroxisome proliferator activated receptors: transcriptional regulators of adipogenesis, lipid metabolism and more". Chemistry & Biology.[26]
  • Walter Wahli. "Evolution and expression of vitellogenin genes". Trends in Genetics.[27]
  • Walter Wahli, Igor B. Dawid, Gerhart U. Ryffel, Toni Wyler, Rolf B. Jaggi, and Rudolf Weber. "Vitellogenin in Xenopus laevis is encoded in a small family of genes". Cell.[28]
  • Walter Wahli. "Peroxisome proliferator-activated receptors (PPARs): from metabolic control to epidermal wound healing". Swiss Medical Weekly.
  • Walter Wahli, Igor B. Dawid, Toni Wyler, Rudolf Weber, and Gerhart U. Ryffel. "Comparative analysis of the structural organization of two closely related vitellogenin genes in X. laevis". cell.[29]
  • W.Wahli. "A gut feeling of the PXR, PPAR and NF-?B connection". Journal of Internal Medicine.[30]
  • Walter WAHLI, Toni WYLER, Rudolf WEBER, and Gerhart U. RYFFEL. "Size, Complexity, and Abundance of a Specific Poly(A)-Containing RNA of Liver from Male Xenopus Induced to Vitellogenin Synthesis by Estrogen". European Journal of Biochemistry.[31]
  • Walter Wahli. "PPAR?: Ally and Foe in Bone Metabolism". Cell Metabolism.[32]
  • Béatrice Desvergne and Walter Wahli. "Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism". Endocrine reviews.[33]
  • Sander Kersten, Béatrice Desvergne & Walter Wahli. "Roles of PPARs in health and disease". Nature.[34]

References

  1. ↑ "Walter". genomyx.ch.
  2. ↑ "Walter Wahli | Metabolomics Congress 2017 | Conferenceseries". www.metabolomicsconference.com. Retrieved 2019-10-24.
  3. ↑ "FBM Awardees 2011". www.genomyx.ch. Retrieved 2019-10-24.
  4. ↑ "Prof. Dr. Walter Wahli". www.swir.ch. Retrieved 2019-10-24.
  5. ↑ Wahli, Walter (2002). "Peroxisome proliferator-activated receptors (PPARs): from metabolic control to epidermal wound healing". Swiss Medical Weekly. 132 (7–8): 83–91. doi:10.4414/smw.2002.09939 (inactive 2019-12-18). ISSN 1424-7860. PMID 11971202. Retrieved 2019-10-27.
  6. ↑ Wahli, W; Martinez, E (1991-06-01). "Superfamily of steroid nuclear receptors: positive and negative regulators of gene expression". The FASEB Journal. 5 (9): 2243–2249. doi:10.1096/fasebj.5.9.1860615. ISSN 0892-6638. PMID 1860615.
  7. ↑ Chen, Jiapeng; Montagner, Alexandra; Tan, Nguan Soon; Wahli, Walter (2018). "Insights into the Role of PPARß/d in NAFLD". International Journal of Molecular Sciences. 19 (7): 1893. doi:10.3390/ijms19071893. PMC 6073272. PMID 29954129.
  8. ↑ Desvergne, Béatrice; Wahli, Walter (1999-10-01). "Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism". Endocrine Reviews. 20 (5): 649–688. doi:10.1210/edrv.20.5.0380. ISSN 0163-769X. PMID 10529898.
  9. ↑ "Unisciences - UNIL - Walter Wahli". applicationspub.unil.ch. Retrieved 2019-10-24.
  10. ↑ "About". www.unil.ch. Retrieved 2019-10-24.
  11. ↑ "Prof. Wahli". www.unil.ch. Retrieved 2019-10-24.
  12. ↑ [1], "Composition for regulating lipid metabolism", issued 2010-04-15 
  13. ↑ [2], "Composition for enhancing immunity", issued 2014-04-22 
  14. ↑ "DNA Tests for Personalized Beauty, Health & Wellness | Imagene Labs". Retrieved 2019-10-24.
  15. ↑ "ICPI website" (PDF). Unknown parameter |url-status= ignored (help)
  16. ↑ "Prof. Dr. Walter Wahli". www.swir.ch. Retrieved 2019-10-24.
  17. ↑ "The Open Nutrition Journal - Editorial Board". opennutritionjournal.com. Retrieved 2019-10-24.
  18. ↑ The Journal of Steroid Biochemistry and Molecular Biology Editorial Board. Search this book on
  19. ↑ "Cell & Bioscience". Cell & Bioscience. Retrieved 2019-10-24.
  20. ↑ "Prof. Wahli". www.unil.ch. Retrieved 2019-10-24.
  21. ↑ "FBM Awardees 2011". www.genomyx.ch. Retrieved 2019-10-24.
  22. ↑ "toulouse infra". Unknown parameter |url-status= ignored (help)
  23. ↑ "International Journal of Molecular Sciences". www.mdpi.com. Retrieved 2019-10-24.
  24. ↑ Wahli, Walter; Michalik, Liliane (2012-07-01). "PPARs at the crossroads of lipid signaling and inflammation". Trends in Endocrinology & Metabolism. 23 (7): 351–363. doi:10.1016/j.tem.2012.05.001. ISSN 1043-2760. PMID 22704720.
  25. ↑ Wahli, W; Martinez, E (1991-06-01). "Superfamily of steroid nuclear receptors: positive and negative regulators of gene expression". The FASEB Journal. 5 (9): 2243–2249. doi:10.1096/fasebj.5.9.1860615. ISSN 0892-6638. PMID 1860615.
  26. ↑ Wahli, W.; Braissant, O.; Desvergne, B. (1995-05-05). "Peroxisome proliferator activated receptors: transcriptional regulators of adipogenesis, lipid metabolism and more…". Chemistry & Biology. 2 (5): 261–266. doi:10.1016/1074-5521(95)90045-4. ISSN 1074-5521. PMID 9383428.
  27. ↑ Wahli, Walter (1988-08-01). "Evolution and expression of vitellogenin genes". Trends in Genetics. 4 (8): 227–232. doi:10.1016/0168-9525(88)90155-2. ISSN 0168-9525. PMID 3072724.
  28. ↑ Wahli, Walter; Dawid, Igor B.; Ryffel, Gerhart U.; Wyler, Toni; Jaggi, Rolf B.; Weber, Rudolf (1979-03-01). "Vitellogenin in Xenopus laevis is encoded in a small family of genes". Cell. 16 (3): 535–549. doi:10.1016/0092-8674(79)90028-X. ISSN 0092-8674. PMID 455441.
  29. ↑ Wahli, Walter; Dawid, Igor B.; Wyler, Toni; Weber, Rudolf; Ryffel, Gerhart U. (1980-05-01). "Comparative analysis of the structural organization of two closely related vitellogenin genes in X. laevis". Cell. 20 (1): 107–117. doi:10.1016/0092-8674(80)90239-1. ISSN 0092-8674. PMID 7388940.
  30. ↑ Wahli, W. (2008). "A gut feeling of the PXR, PPAR and NF-?B connection". Journal of Internal Medicine. 263 (6): 613–619. doi:10.1111/j.1365-2796.2008.01951.x. ISSN 1365-2796. PMID 18479261.
  31. ↑ Wahli, Walter; Wyler, Toni; Weber, Rudolf; Ryffel, Gerhart U. (1976). "Size, Complexity and Abundance of a Specific Poly(A)-Containing RNA of Liver from Male Xenopus Induced to Vitellogenin Synthesis by Estrogen". European Journal of Biochemistry. 66 (3): 457–465. doi:10.1111/j.1432-1033.1976.tb10570.x. ISSN 1432-1033. PMID 954751.
  32. ↑ Wahli, Walter (2008-03-05). "PPAR?: Ally and Foe in Bone Metabolism". Cell Metabolism. 7 (3): 188–190. doi:10.1016/j.cmet.2008.02.005. ISSN 1550-4131. PMID 18316021.
  33. ↑ Desvergne, Béatrice; Wahli, Walter (1999-10-01). "Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism". Endocrine Reviews. 20 (5): 649–688. doi:10.1210/edrv.20.5.0380. ISSN 0163-769X. PMID 10529898.
  34. ↑ Kersten, Sander; Desvergne, Béatrice; Wahli, Walter (2000-05-05). "Roles of PPARs in health and disease". Nature. 405 (6785): 421–424. Bibcode:2000Natur.405..421K. doi:10.1038/35013000. ISSN 1476-4687. PMID 10839530.


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