Younes Medkour
| Younes Medkour | |
|---|---|
| Born | August 20, 1993 Batna, Algeria |
| 🏳️ Nationality | Algerian Canadian |
| 🎓 Alma mater | Concordia University (BS, PhD) |
| 💼 Occupation | Postdoctoral Fellow |
| Known for | Discovery of the most potent anti-aging group of phytochemicals. |
| 🌐 Website | younesmedkour.com |
Younes Medkour (born August 20, 1993)[1] is a Canadian biologist and a postdoctoral fellow studying metabolic disorders at McGill University[2]. He is known for his research on aging, which focused on lifespan extension using phytochemicals[3]. Younes has also co-founded two businesses: NBT Consultants and RYM Labs.
Early life and education
Younes Medkour was born in Batna (Algeria) in 1993[1], and grew up in Montreal (Canada). His family emigrated to Canada in 2002 and has been living there since then[1]. Medkour obtained a Bachelor of Science at Concordia University in biology[3]. In 2020, he received a Ph.D. in cell and molecular biology[3] from the same school, focusing on the mechanisms underlying aging in yeast. In 2018, he was appointed as one of Concordia University's Public Scholar—a group of select students whose mandate is to connect with the community and represent the university's body of research.[4]
Research
While Medkour was in Vladimir Titorenko's laboratory and in collaboration with Idunn Technologies, he discovered a group of anti-aging compounds that significantly increase lifespan.[5]. His doctoral work then focused on elucidating the mechanisms through which the most potent of these phytochemicals—a natural extract from the white willow Salix alba—delays yeast chronological aging[6]. This mechanism integrates an age-related form of liponecrotic cell death, the unfolded protein response in the endoplasmic reticulum, and mitochondrial functionality into a network governed by a nutrient-sensing protein kinase[6]
His discoveries in the laboratory of Vladimir Titorenko have been published in the reputable scientific journal Oncotarget[5][6][7][8] and highlighted by multiple media outlets including Algerian Television[9][10], The Montreal Gazette[11], Concordia University's news[12], TVA nouvelles[13], and others.
In 2020, he joined the laboratory of Vincent Giguère at the Goodman Cancer Research Institute of McGill University to study metabolic disorders.[1]. He aims to solve the precise molecular mechanism through which oxidative stress regulates the estrogen-related receptors—a group of orphan nuclear receptors that serve as master regulators of metabolism[1]. He is also working on characterizing the implication of this novel regulatory mechanism in the action of insulin and its contributions to type 2 diabetes[1]
Entrepreneurship
In 2021, Medkour co-founded NBT Consultants—a Montreal-born biotechnology consulting firm that has for mission to help young entrepreneurs think and develop their biotechnology project by providing them with scientific insights and by vetting their science.
He also is the CEO and co-founder of RYM Labs—a company that aims to help start-ups think and implement their IT ecosystem. This company operates in Algeria and Canada.
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 E-ChemTalks - Younes MEDKOUR -, retrieved 2021-10-24
- ↑ "Younes Medkour, PhD". scholar.google.ca. Retrieved 2021-10-24.
- ↑ 3.0 3.1 3.2 "Younes Medkour". www.concordia.ca. Retrieved 2021-10-24.
- ↑ "Concordia's Public Scholars: communicating their cutting-edge research". montrealgazette. Retrieved 2021-10-24.
- ↑ 5.0 5.1 Lutchman, Vicky; Medkour, Younes; Samson, Eugenie; Arlia-Ciommo, Anthony; Dakik, Pamela; Cortes, Berly; Feldman, Rachel; Mohtashami, Sadaf; McAuley, Mélissa; Chancharoen, Marisa; Rukundo, Belise (2016-02-24). "Discovery of plant extracts that greatly delay yeast chronological aging and have different effects on longevity-defining cellular processes". Oncotarget. 7 (13): 16542–16566. doi:10.18632/oncotarget.7665. ISSN 1949-2553.
- ↑ 6.0 6.1 6.2 Medkour, Younes; Mohammad, Karamat; Arlia-Ciommo, Anthony; Svistkova, Veronika; Dakik, Pamela; Mitrofanova, Darya; Rodriguez, Monica Enith Lozano; Junio, Jennifer Anne Baratang; Taifour, Tarek; Escudero, Paola; Goltsios, Fani-Fay (2019-10-08). "Mechanisms by which PE21, an extract from the white willow Salix alba , delays chronological aging in budding yeast". Oncotarget. 10 (56): 5780–5816. doi:10.18632/oncotarget.27209. ISSN 1949-2553.
- ↑ Leonov, Anna; Arlia-Ciommo, Anthony; Bourque, Simon D.; Koupaki, Olivia; Kyryakov, Pavlo; Dakik, Pamela; McAuley, Mélissa; Medkour, Younes; Mohammad, Karamat; Maulo, Tamara Di; Titorenko, Vladimir I. (2017-03-31). "Specific changes in mitochondrial lipidome alter mitochondrial proteome and increase the geroprotective efficiency of lithocholic acid in chronologically aging yeast". Oncotarget. 8 (19): 30672–30691. doi:10.18632/oncotarget.16766. ISSN 1949-2553.
- ↑ Dakik, Pamela; Rodriguez, Monica Enith Lozano; Junio, Jennifer Anne Baratang; Mitrofanova, Darya; Medkour, Younes; Tafakori, Tala; Taifour, Tarek; Lutchman, Vicky; Samson, Eugenie; Arlia-Ciommo, Anthony; Rukundo, Belise (2020-06-09). "Discovery of fifteen new geroprotective plant extracts and identification of cellular processes they affect to prolong the chronological lifespan of budding yeast". Oncotarget. 11 (23): 2182–2203. doi:10.18632/oncotarget.27615. ISSN 1949-2553. PMC 7289529 Check
|pmc=value (help). PMID 32577164 Check|pmid=value (help). - ↑ JT20H 31 07 2019, retrieved 2021-10-24
- ↑ Canada #Diaspora Ep01 ENTV06, retrieved 2021-10-24
- ↑ "Eliminating age-related diseases is a worthy, attainable goal". Montreal Gazette. Retrieved 2021-10-24. Unknown parameter
|url-status=ignored (help) - ↑ "New research: the best anti-ageing compounds to keep you young". www.concordia.ca. Retrieved 2021-10-24.
- ↑ "Six plantes miracles pour lutter contre le vieillissement". TVA Nouvelles. Retrieved 2021-10-24.
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