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Yulong Li

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Yulong Li
BornChina
🏳️ NationalityChinese
🎓 Alma materPeking University (B.S.)
Duke University (PhD)
💼 Occupation
🌐 Websiteyulonglilab.org

Yulong Li (Chinese: 李毓龙; born in 1978) is a Chinese neuroscientist. Currently he is a professor in the School of Life Sciences at Peking University, a principal investigator of PKU-THU Center for Life Sciences and IDG/McGovern Institute for Brain Research at Peking University.[1][2][3]

Education and early life[edit]

Li was born and raised in Fujian Province, China. He received his B.S. with a major in biophysics and physiology at Peking University in 2000. He joined George Augustine’s lab at Duke University and received his Ph.D. in 2006. From 2006 to 2012, he conducted his postdoctoral research in Richard Tsien’s lab at Stanford University.[4]

Research[edit]

In 2012, Li joined Peking University as a principal investigator. His research interests focus on developing advanced biophotonic sensors to understand the communication between neurons. His group has developed a series of novel genetically-encoded fluorescent sensors for real-time detection of neurotransmitters and neuromodulators in vivo, such as ACh, DA and NE, called GRAB (GPCR activation based) sensors.[5][6][7][8][9][10][11] His group also developed the first entire genetically-encoded optogenetic method PARIS (pairing actuators and receivers to optically isolate gap junctions) for functionally mapping gap junctions.[12] Besides the tool development, his group is also interested in the functions of GPCRs. They are one of the groups (See also [14] and [15] providing complementary evidence) independently deorphanized primate specific Mas-related GPCR member X4 (MRGPRX4) with its native substrate bile acids, and identified its physiological function in mediating cholestatic itch.[13][14][15]

Awards[edit]

2019 XPLORER PRIZE in Life Sciences[16]

2019 The National Science Fund for Distinguished Young Scholars[17] [18]

2019 The 12th "Tan Jiazhen Life Science Innovation Award" [19][20]

2019 Zhang Xiangtong Neuroscience Young Scientist Award [21] [22]

2019 “Excellence in Teaching” award, School of Life Sciences, Peking University [23]

2019 The 20th Wu Jieping – Paul Janssen Medical & Pharmaceutical Award [24]

2018 Research was selected into the Top Ten Progress of Life Sciences in China [25]

2018 Research was selected into the Top Ten News of Medical Science and Technology in China [26] [27]

2018 VCANBIO Award for Innovations and Breakthrough in Life Sciences and Medicine [28]

2018 PKU & Boehringer-Ingelheim Faculty Research Award [29]

2015 “Green Leaf Eminent Young Scholar” Fellowship, Luye Pharma Group Co.,Ltd [30]

2015 “Excellence in Teaching” award, School of Life Sciences, Peking University

2014 1000-Young-talents program, China Organization Department, Beijing [31]

2013 Junior faculty teaching awards, Peking University, Beijing [32]

References[edit]

  1. [1]
  2. [2]
  3. [3]
  4. [4]
  5. [ Jing, M., Zhang, P., Wang, G., Feng, J., Mesik, L., Zeng, J., Jiang, H., Wang, S., Looby, J. C., Guagliardo, N. A., Langma, L. W., Lu, J., Zuo, Y., Talmage, D. A., Role, L. W., Barrett, P. Q., Zhang, L. I., Luo, M., Song, Y., Zhu, J. J., & Li, Y. (2018, 2018/09/01). A genetically encoded fluorescent acetylcholine indicator for in vitro and in vivo studies. Nature Biotechnology, 36(8), 726-737. https://doi.org/10.1038/nbt.4184 https://www.nature.com/articles/nbt.4184]
  6. [5]
  7. [ Jing, M., Li, Y., Zeng, J., Huang, P., Skirzewski, M., Kljakic, O., Peng, W., Qian, T., Tan, K., Zou, J., Trinh, S., Wu, R., Zhang, S., Pan, S., Hires, S. A., Xu, M., Li, H., Saksida, L. M., Prado, V. F., Bussey, T. J., Prado, M. A. M., Chen, L., Cheng, H., & Li, Y. (2020, 2020/11/01). An optimized acetylcholine sensor for monitoring in vivo cholinergic activity. Nature Methods, 17(11), 1139-1146. https://doi.org/10.1038/s41592-020-0953-2 https://www.nature.com/articles/s41592-020-0953-2?proof=t]
  8. [ Sun, F., Zeng, J., Jing, M., Zhou, J., Feng, J., Owen, S. F., Luo, Y., Li, F., Wang, H., Yamaguchi, T., Yong, Z., Gao, Y., Peng, W., Wang, L., Zhang, S., Du, J., Lin, D., Xu, M., Kreitzer, A. C., Cui, G., & Li, Y. (2018). A Genetically Encoded Fluorescent Sensor Enables Rapid and Specific Detection of Dopamine in Flies, Fish, and Mice. Cell, 174(2), 481-496.e419. https://doi.org/10.1016/j.cell.2018.06.042]
  9. [6]
  10. [ Sun, F., Zhou, J., Dai, B., Qian, T., Zeng, J., Li, X., Zhuo, Y., Zhang, Y., Wang, Y., Qian, C., Tan, K., Feng, J., Dong, H., Lin, D., Cui, G., & Li, Y. (2020, 2020/11/01). Next-generation GRAB sensors for monitoring dopaminergic activity in vivo. Nature Methods, 17(11), 1156-1166. https://doi.org/10.1038/s41592-020-00981-9 ]
  11. [ Feng, J., Zhang, C., Lischinsky, J. E., Jing, M., Zhou, J., Wang, H., Zhang, Y., Dong, A., Wu, Z., Wu, H., Chen, W., Zhang, P., Zou, J., Hires, S. A., Zhu, J. J., Cui, G., Lin, D., Du, J., & Li, Y. (2019). A Genetically Encoded Fluorescent Sensor for Rapid and Specific In Vivo Detection of Norepinephrine.Neuron,102(4),745-761.e748. https://doi.org/10.1016/j.neuron.2019.02.037 ]
  12. [ Wu, L., Dong, A., Dong, L., Wang, S.-Q., & Li, Y. (2019, 2019/01/14). PARIS, an optogenetic method for functionally mapping gap junctions. eLife, 8, e43366. https://doi.org/10.7554/eLife.43366]
  13. [ Yu, H., Zhao, T., Liu, S., Wu, Q., Johnson, O., Wu, Z., Zhuang, Z., Shi, Y., Peng, L., He, R., Yang, Y., Sun, J., Wang, X., Xu, H., Zeng, Z., Zou, P., Lei, X., Luo, W., & Li, Y. (2019, 2019/09/10). MRGPRX4 is a bile acid receptor for human cholestatic itch. eLife, 8, e48431. https://doi.org/10.7554/eLife.48431.]
  14. [ Meixiong, J., Vasavda, C., Snyder, S. H., & Dong, X. (2019, May 21). MRGPRX4 is a G protein-coupled receptor activated by bile acids that may contribute to cholestatic pruritus. Proc Natl Acad Sci U S A, 116(21), 10525-10530. https://doi.org/10.1073/pnas.1903316116.]
  15. [ Wolf K, Kühn H, Leibl V, Gebhardt L, Glaudo M, Reeh P, et al. Bile salt subspecies activate the G protein-coupled receptor MRGX4 expressed on sensory neurons and cause itching in humans. Hepatology (Baltimore, Md). 2019;70(S1):769A.]
  16. "2019年"科学探索奖"获奖名单".
  17. "2019年度国家杰出青年科学基金".
  18. "2019国家杰青基金名单公布 北大22人居全国第一".
  19. "第十二届谈家桢生命科学奖颁奖大会在南开大学举行".
  20. "李毓龙研究员获第十二届谈家桢生命科学创新奖".
  21. "2019年张香桐神经科学青年科学家奖、张香桐神经科学优秀研究生论文奖评审结果".
  22. "李毓龙、于翔获2019年张香桐神经科学青年科学家奖".
  23. ""最受欢迎教师"——李毓龙老师专访 SKY·学术".
  24. "第二十届吴阶平-保罗·杨森医学药学奖(吴杨奖)".
  25. "生命中心李毓龙研发成果入选2018年度"中国生命科学十大进展"".
  26. "生命中心李毓龙研发成果入选2018年度"中国生命科学十大进展"".
  27. " "多项成果入选2018 年 "中国生命科学十大进展"、"中国 十大医学科技新闻"".
  28. " "中源协和生命医学奖".
  29. "勃林格殷格翰研究员奖颁奖仪式暨第二届北京大学-勃林格殷格翰生物医学研究联合论坛顺利召开".
  30. "绿叶生物医药杰出青年学者奖".
  31. http://bio.pku.edu.cn/homes/Index/news_cont_jl/16/43.html. Missing or empty |title= (help)
  32. "北京大学第十三届青年教师教学基本功比赛成绩揭晓".

External links[edit]


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