Zimei Bu
From EverybodyWiki Bios & Wiki
Zimei Bu is a protein chemist in the City College of New York, where she is Professor of Chemistry and Biochemistry and Laboratory Director.[1][2]
Bu studies protein structure and dynamics by NMR,[4] small angle X-ray scattering and small angle neutron scattering. With her colleagues she studied protein domain dynamics [5] by neutron spin echo spectroscopy to observe protein nanomachines in motion,[3][6][7] related to therapeutics for cancer metastasis. [8][9][10]
References
- ↑ "Professor Zimei Bu". 14 July 2015.
- ↑ "Zimei Bu, PhD".
- ↑ 3.0 3.1 Bu Z; Biehl R; Monkenbusch M; Richter D; Callaway DJ (2005). "Coupled protein domain motion in Taq polymerase revealed by neutron spin-echo spectroscopy". Proc Natl Acad Sci USA. 102 (49): 17646–17651. Bibcode:2005PNAS..10217646B. doi:10.1073/pnas.0503388102. PMC 1345721. PMID 16306270.
- ↑ Bu Z, Shi Y, Callaway DJ, Tycko R (January 2007). "Molecular alignment within β-sheets in Aβ14-23 fibrils: solid-state NMR experiments and theoretical predictions". Biophysical Journal. 92 (2): 594–602. Bibcode:2007BpJ....92..594B. doi:10.1529/biophysj.106.091017. PMC 1751388. PMID 17056725.
- ↑ Bu Z, Callaway DJ (2011). "Proteins move! Protein dynamics and long-range allostery in cell signaling". In Donev R. Protein Structure and Diseases. Advances in Protein Chemistry and Structural Biology. 83. Academic Press. pp. 163–221. doi:10.1016/B978-0-12-381262-9.00005-7. ISBN 9780123812629. PMID 21570668. Search this book on
- ↑ Farago B, Nicholl ID, Wang S, Cheng X, Callaway DJ, Bu Z (March 30, 2021). "Activated nanoscale actin-binding domain motion in the catenin-cadherin complex revealed by neutron spin echo spectroscopy". Proc Natl Acad Sci USA. 118 (13). Bibcode:2021PNAS..11825012F. doi:10.1073/pnas.2025012118. PMC 8020631 Check
|pmc=value (help). PMID 33753508 Check|pmid=value (help). Unknown parameter|article-number=ignored (help) - ↑ Farago B, Li J, Cornilescu G, Callaway DJ, Bu Z (November 2010). "Activation of Nanoscale Allosteric Protein Domain Motion Revealed by Neutron Spin Echo Spectroscopy". Biophysical Journal. 99 (10): 3473–3482. Bibcode:2010BpJ....99.3473F. doi:10.1016/j.bpj.2010.09.058. PMC 2980739. PMID 21081097.CS1 maint: Multiple names: authors list (link)
- ↑ Bush M, Alhanshali BM, Qian S, Stanley C, Heller W, Matsui T, Weiss T, Nicholl ID, Walz T, Callaway DJ, Bu Z (October 22, 2019). "An ensemble of flexible conformations underlies mechanotransduction by the cadherin-catenin adhesion complex". Proc Natl Acad Sci USA. 116 (43): 21545–21555. Bibcode:2019PNAS..11621545B. doi:10.1073/pnas.1911489116. PMC 6815173 Check
|pmc=value (help). PMID 31591245. - ↑ Callaway DJ, Nicholl ID, Shi B, Reyes G, Farago B, Bu Z (2024). "Nanoscale dynamics of the cadherin-catenin complex bound to vinculin revealed by neutron spin echo spectroscopy". Proceedings of the National Academy of Sciences of the United States of America. 129 (39). Bibcode:2024PNAS..12108459C. doi:10.1073/pnas.2408459121. PMC 11441495 Check
|pmc=value (help). PMID 39298480 Check|pmid=value (help). Unknown parameter|article-number=ignored (help) - ↑ Callaway DJ, Bu Z (2017). "Visualizing the nanoscale: protein internal dynamics and neutron spin echo spectroscopy". Curr. Opin. Struct. Biol. 42: 1–5. doi:10.1016/j.sbi.2016.10.001. PMC 5374024. PMID 27756047.
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