Zymo Research Corporation
| File:Zymoresearchlogo.png | |
| Private | |
| ISIN | 🆔 |
| Industry | Biotechnology |
| Founded 📆 | 1994 |
| Founder 👔 | Larry Jia |
| Headquarters 🏙️ | Irvine, CA (headquarters) |
Area served 🗺️ | |
Key people | Larry Jia (Chairman and CEO) |
| Members | |
Number of employees | |
| 🌐 Website | www.zymoresearch.com |
| 📇 Address | |
| 📞 telephone | |
Zymo Research is a privately held American manufacturer of molecular biology research tools used for DNA and RNA research and analysis. The company also supports epigenetics research, the field of medicine studying stable heritable traits that cannot be explained by changes in DNA sequence.
History[edit]
Zymo Research Corporation was founded by Larry Jia in 1994. The company started its home base in Orange, CA in a garage, manufacturing products for DNA and RNA extraction and purification and other specialty products for E. coli and yeast based research. It expanded its product offerings to include tools for epigenetics research. In December 2010, the company relocated to Irvine, CA.[citation needed]
In 2009, Zymo Research Europe was established in Freiburg, Germany. It works as a distribution support hub for Europe and the Middle East and will also be initiating research and development programs at a new facility, intended for state-of-the-art researching.[when?]
Products[edit]
The company is a supplier of DNA extraction and RNA extraction kit products used to isolate and purify DNA and RNA from various sample sources ranging from tough to lyse environmental samples to tissue, blood, urine,[1] and serum samples.[2][not in citation given]
The company expanded and by 2016 was a recognized epigenetics company in competition with Epigentek,[3] offering products in DNA methylation and DNA hydroxymethylation; the company's work in this area, though, began before 2010.[4] The company showcased its "EZ DNA Methylation-Lightening" kit for bisulfate DNA conversion at the 2013 AACR meeting.[5] As of the second quarter of 2013, Zymo was "the only provider for genome-wide 5-hydroxymethylcytosine analysis services at the single-nucleotide resolution."[6]
During the 2019–20 coronavirus pandemic, Zymo Research began development of an at-home testing kit for use by first-responders and companies for employee testing; as of March 2020[update], Zymo was waiting for FDA approval.[7]
Research[edit]
A review of PubMed indicates that scientists at Zymo have contributed to a couple of dozen peer reviewed manuscripts. Of these, two were authored exclusively by Zymo personnel, and a third was authored substantially by Zymo personnel.[bib 1][bib 2][bib 3] Predating these publications, the company's research on methods for DNA methylation analysis using bisulfate treatment was reported in 2010 in the trade press.[4]
Distribution[edit]
The company's products are distributed in North America and internationally through distributors located in Europe, Asia, South America, Africa, Australia, and others.
References[edit]
- ↑ Jain S, Lin SY, Song W, Su YH (23 April 2019). "Urine-Based Liquid Biopsy for Nonurological Cancers". Genetic Engineering & Biotechnology News. Approaches for the Enrichment of Urine cfDNA. Retrieved 4 April 2020.
- ↑ Oswald, Dr. Nick (21 January 2008). "Preps in the Zyppy: How I Changed my DNA Miniprep, Gel Extraction and Concentrator Kits". BiteSizeBio. New England Biolabs. Retrieved 4 April 2020. Unknown parameter
|url-status=ignored (help) - ↑ Jones, Rob Ranulph (31 August 2016). "Awaken Dormant DNA, Epigenetically". Genetic Engineering & Biotechnology News. Vol. 36 no. 15. Vendor Interest. Retrieved 4 April 2020.
- ↑ 4.0 4.1 Stein, Richard A. A. (1 February 2010). "Insights Accrue on Epigenetic Modification". Genetic Engineering & Biotechnology News. Vol. 30 no. 3. Sidebar: Bisulfite Treatment for the Detection of DNA Methylation. Retrieved 4 April 2020.
- ↑ Staff (15 May 2013). "Highlights from AACR". Genetic Engineering & Biotechnology News. Retrieved 4 April 2020.
- ↑ Stein, Richard A. A. (1 May 2013). "Exposing the Exposome". Genetic Engineering & Biotechnology News. Retrieved 4 April 2020.
- ↑ Johnson, Carolyn; McGinley, Laurie; Eilperin, Juliet; Brown, Emma (17 March 2020). "DIY nasal swabs, drive-thrus and labs in overdrive: Americans are desperate for more coronavirus testing". The Washington Post. Retrieved 4 April 2020. Unknown parameter
|url-status=ignored (help)
Company bibliography[edit]
- ↑ Tan D, Chung TH, Sun X, Jia XY (20 November 2018). "Mirror Bisulfite Sequencing: A Method for Single-Base Resolution of Hydroxymethylcytosine". Analytical Chemistry. 90 (22): 13200–13206. doi:10.1021/acs.analchem.8b02832. PMID 30345735 – via bioRχiv.
- ↑ Sun X, Chung TH, Tan D, Kim A (February 2016). "Practical Guidelines and Consideration of Using RRHP for 5hmC Detection". Epigenomics (Review). London: Future Medicine. 8 (2): 225–235. doi:10.2217/epi.15.105. PMID 26791605.
- ↑ Cui L, Chung TH, Tan D, Sun X, Jia XY (November 2014). "JBP1-seq: A Fast and Efficient Method for Genome-Wide Profiling of 5hmC". Genomics. 104 (5): 368–375. doi:10.1016/j.ygeno.2014.08.023. PMID 25218799 – via Elsevier ScienceDirect.
Further reading[edit]
- Dove, Alan (9 October 2009). "Epigenetics: The Final Frontier?". Science (Special Advertising Feature). AAAS. doi:10.1126/science.opms.p0900038. Archived from the original on 17 November 2010. Unknown parameter
|url-status=ignored (help)
External links[edit]
- Official Website
- Postings about Zymo Research at the EpiGenie blog (surveillance for epigenetic press and publications)
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