ATG (autophagy acronym)
ATG is short for "AuTophaGy"-related, which is applied to both genes and proteins related to the biological process of autophagy.[1] There are about 16-20 conserved ATG genes coding for many core ATG proteins conserved from yeast to humans.[1] ATG may be part of the protein name (such as ATG7) or part of the gene name (such as ATG7).[2], although all ATG proteins and genes do not follow this pattern (such as ULK1 and ULK1).[1]
To give specific examples, the UKL1 enzyme (kinase complex) induces autophagosome biogenesis, and ATG13 (Autophagy-related protein 13) is required for phagosome formation.[3]
References[edit]
- ↑ 1.0 1.1 1.2 Levine B, Kroemer G (2019). "Biological Functions of Autophagy Genes: A Disease Perspective". Cell. 176 (1–2): 11–42. doi:10.1016/j.cell.2018.09.048. PMC 6347410. PMID 30633901.
- ↑ Kuo C, Hansen M, Troemel E (2018). "Autophagy and innate immunity: Insights from invertebrate model organisms". Autophagy. 14 (2): 33–242. doi:10.1080/15548627.2017.1389824. PMC 5902216. PMID 29130360.
- ↑ Metur SP, Lei Y, Zhang Z, Klionsky DJ (2023). "Regulation of autophagy gene expression and its implications in cancer". Journal of Cell Science. 136 (10): jcs260631. doi:10.1242/jcs.260631. PMC 10214848 Check
|pmc=value (help). PMID 37199330 Check|pmid=value (help).
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