Aminopentamide
From EverybodyWiki Bios & Wiki
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| Clinical data | |
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| Synonyms | Dimevamide, Centrine. |
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| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}} |
| Chemical and physical data | |
| Formula | C19H24N2O |
| Molar mass | 296.414 g·mol−1 |
| 3D model (JSmol) | |
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Anticholinergic, antispasmodic drug; also bird and rodent repellent. Part of the structure is clearly similar to Darifenacin. Functionalizing the primary amide would be consistent with narcotic analgesic potency, as for example moramide.
Synthesis:[1]
Abs config:[2] Cryst:[3] Pharmacol:[4] (ord, uv):[5]
See also
References
- ↑ Moffett, Robert Bruce; Aspergren, Brooke D. (1957). "Antispasmodics. X. α,α-Diphenyl-γ-amino Amides1". Journal of the American Chemical Society. 79 (16): 4451–4457. doi:10.1021/ja01573a056.
- ↑ Beckett, A. H.; Casy, A. F. (1957). "600. Configurational studies in synthetic analgesics. Part III. The configuration of (–)-phenadoxone". J. Chem. Soc. 0 (0): 3076–3079. doi:10.1039/JR9570003076.
- ↑ Colleter, J.C. et al, Bull. Soc. Pharm. Bordeaux, 1961, 100, 87 (cryst struct)
- ↑ Yusuf, S.M. et al, Arch. Intern. Pharmacodyn., 1964, 152, 198 (pharmacol)
- ↑ Crabbe, P. et al, Bull. Soc. Chim. Fr., 1965, 2855 (ord, uv)
Template:Acetylcholine receptor modulators
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