Antigenic Essence
- Response to comment
Hello. On May 21, 2022 you reviewed my draft page (Draft:Antigenic Essence) and left a comment. Thank you. You are absolutely right; the first 2 references refer to the group of scientists who introduced the term Antigenic Essence. This group of scientists has other scientific publications on antigenic essence and related technology such as: Cancers 2021, 13: 774, Vaccines 2019, 7 (4): 186, Recent Patents on Biotechnology 2017, 11(1): 32–41, Journal of Immunology Research 2016. Article ID 5031529, Human Vaccines & Immunotherapeutics 2015, 11(3): 689-698, Human Vaccines & Immunotherapeutics 2013, 9(1): 198-209, Human Vaccines & Immunotherapeutics 2013, 9(7): 1549-1552, Molecular & cellular proteomics 2012, 11(2): M111.014480, Journal of Carcinogenesis & Mutagenesis 2010, 1: 1–3, Journal of Cancer Science & Therapy 2010, 2: 126–131, Journal of Cancer 2010, 1: 230-241, Rapid Communications in Mass Spectrometry 2009, 23: 680–682 and others.
I have not listed them as they seem unnecessary and do not further reveal the term Antigenic Essence. However, these publications are cited by other scientists in well-known scientific peer-reviewed journals more than 150 times (according to Google Scholar). It means that the term and related technology is already circulating in the science. Here, you can find the extended explanation of Antigenic Essence: https://encyclopedia.pub/entry/10569.
As for other references, I provided them as external sources. In reference 3 and 5, the Antigenic Essence is considered as one of the 5 most promising platforms for the development of cancer vaccines today, which could justify the publication of at least the definition of Antigenic Essence in Wikipedia.
Reference 3 is a book (reference was corrected). Reference 4 may be removed.
Thank you for your comment and I will be waiting to hear back from you and would also welcome an expert opinion from someone at WP:WikiProject Molecular Biology/Molecular and Cell Biology. 18:34, 26 May 2022 Steven Lichtenberg (talk contribs)
Antigenic essence is a drug substance obtained from the surface of cells and consisting of a diversity of antigens that determine antigenic properties of cells. [1] Antigenic essence does not include intracellular antigens that are inaccessible to the immune system, so its composition is close to the actual antigenic profile of cells. Antigenic essence is obtained from the cell surface by treating live cells with a protease under specific conditions.
The technology for obtaining antigenic essence was developed in 2005-2020 under the guidance of prof. Petr Lokhov, who introduced the term "antigenic essence" in 2013.[2] It is expected that antigenic essence can be used for the development of cancer vaccines, as it may have sufficient advantages over vaccination with inactivated whole cancer cells, which have previously been widely tested as cancer vaccines.[3][4][5][6]
References
- ↑ Lokhov, Petr G.; Balashova, Elena E. (12 February 2021). "Antigenic Essence: Upgrade of Cellular Cancer Vaccines". Cancers. 13 (4): 774. doi:10.3390/cancers13040774. ISSN 2072-6694. PMC 7917603 Check
|pmc=value (help). PMID 33673325 Check|pmid=value (help). - ↑ Lokhov, Petr G.; Balashova, Elena E. (9 April 2013). "Universal cancer vaccine: an update on the design of cancer vaccines generated from endothelial cells". Human Vaccines & Immunotherapeutics. 9 (7): 1549–1552. doi:10.4161/hv.24300. ISSN 2164-554X. PMID 23571178. Unknown parameter
|s2cid=ignored (help) - ↑ Research and Markets, Ingenious e-Brain Solutions. Report 2022. "Cancer Vaccine Platforms". www.researchandmarkets.com. Retrieved 2022-04-25.
- ↑ "Deep Knowledge Group: Deep Pharma Intelligence Releases Analytical Study "5 High-impact Cancer Vaccine Platforms"". Bloomberg.com. 2021-12-08. Retrieved 2022-04-25.
- ↑ "The Landscape of Cancer Vaccines and Research Platforms: The Cutting Edge". www.biopharmatrend.com. Retrieved 2022-04-25.
- ↑ "The Search for a Cancer Vaccine: Have We Been Doing It All Wrong? - Built WIth Biology". www.builtwithbiology.com. Retrieved 2022-04-25.
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