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Antoni Areas

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Antoni Areas were discovered by Swedish neurologist Nils Antoni in 1920.[1] Antoni Areas are distinct histopathologic cells required to diagnose a Schwannomas. Two types exist: Antoni A and Antoni B. Antoni A are referred to as the nuclear palisading eosinophilic cellular areas densely compacted with Schwann cells.[2][3] Antoni A areas are associated with Verocay bodies.[3] Antoni B areas are hypocellular, loosely arranged myxoid or hyalinized stroma that is at times filled with deformed blood vessels or degenerated Antoni A tissue.[4] Antoni B areas can be lacking in large mitotically active schwannomas and it will mimic a sarcoma.[3] Within a schwannoma, these areas are arranged in a fascicle format with an alternating pattern of dense and loose cellular areas.[3]

References[edit]

  1. Joshi, Rajiv (2012). "Learning from eponyms: Jose Verocay and Verocay bodies, Antoni A and B areas, Nils Antoni and Schwannomas". Indian Dermatology Online Journal. 3 (3): 215. doi:10.4103/2229-5178.101826.
  2. Ramnani, Dharam. "Dr". WebPathology, LLC. WebPathology, LLC. Retrieved 20 February 2020.
  3. 3.0 3.1 3.2 3.3 Pytel, Peter; Anthony, Douglas C. (2015). Kumar, Vinay; Abbas, Abul K.; Aster, Jon C., eds. Robbins and Cotran Pathologic Basis of Disease. Philadelphia, PA: Elsevier/Saunders. p. 1247. ISBN 978-1-4557-2613-4. Search this book on
  4. Joshi, Rajiv (2012). "Learning from eponyms: Jose Verocay and Verocay bodies, Antoni A and B areas, Nils Antoni and Schwannomas". Indian Dermatology Online Journal. 3 (3): 215. doi:10.4103/2229-5178.101826.


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