Chemical resistomics
The term Resistome was firstly proposed by Gerard D. Wright.[1] for the collection of all the antibiotic resistance genes and their precursors in both pathogenic and non-pathogenic bacteria, while Chemical Resistomics is the term proposed by Saha et al., 2018 [2] [3]for the prediction of bacterial resistance genes likely to cause resistance against a specific drug, based upon drug's chemical and structural features. Based on this approach, one R package, uCAREChemSuiteCLI[4] and an online tool, uCARE Chem Suite[5] was developed for Resistome prediction [6].
Since its presence in Comprehensive R Archive Network in 2018, the uCAREChemSuiteCLI has been downloaded for more than 12000 time globally [7]
See also[edit]
References[edit]
- ↑ Wright GD (March 2007). "The antibiotic resistome: the nexus of chemical and genetic diversity". Nature Reviews Microbiology. 5 (3): 175–186. doi:10.1038/nrmicro1614.
- ↑ Saha S.B., Gupta V.K. and Ramteke P.W. (2021). uCARE Chem Suite and uCAREChemSuiteCLI: Tools for bacterial resistomeprediction. Genes & Diseases, 8(5): 721-729. https://doi.org/10.1016/j.gendis.2020.06.008
- ↑ Saha, S.; Gupta, V.K.; Ramteke, P.W. "uCARE Chem Suite and uCAREChemSuiteCLI: An online tool and a standalone R package for the prediction of drug resistome". International Journal of Infectious Diseases. 101: 21. doi:10.1016/j.ijid.2020.09.093.
- ↑ Ramteke, Saurav Bhaskar Saha and Pramod Wasudeo (2019-06-03), uCAREChemSuiteCLI: Resistome Predicter, retrieved 2023-01-25
- ↑ "uCARE Chem Suite V.02". sauravsaha.shinyapps.io. Retrieved 2023-01-25.
- ↑ "AMR Curation: A public repository for collective curation of antimicrobial resistance (AMR) genes, maintained and monitored by Comprehensive Antibiotic Resistance Database Team". Retrieved January 25, 2023. Unknown parameter
|url-status=ignored (help) - ↑ "CRAN Logs". Retrieved January 25, 2023. Unknown parameter
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