Lynn Dalgarno
| Lynn Dalgarno | |
|---|---|
| Born | 12 November 1935 |
| 🏳️ Nationality | Australian |
| 🎓 Alma mater | Australian National University |
| 💼 Occupation | |
| Known for | Shine-Dalgarno sequence |
Lynn Dalgarno (born 12 November 1935) is an Australian geneticist known for the discovery of the Shine-Dalgarno sequence with his graduate student, John Shine.[1][2][3]
Life
Early career research
Dalgarno obtained a Bachelor of Agricultural Science (BAgrSc) in 1958 from the Australian National University.
Independent research career
The Shine-Dalgarno Sequence
Career timeline
- 1958 - BAgrSc from ANU
- Research with F. J. R. Hird at the Departments of Biochemistry and Agriculture, University of Melbourne[4]
- 1962 - Ph.D. from ANU, "Respiratory metabolism and processes of uptake in a plant tissue"
- Research with L. M. Birt at The Russell Grimwade School of Biochemistry, University of Melbourne[5][6][7][8]
- 1963 - Medical Research Council's National Institute for Medical Research with Edward M. Martin[9][10][11][12]
- Collaborations with E. Horton, S. L. Liu, T. S. Work, and R. A. Cox
- 1965 - Institut de Biologie Physico-Chimique with François Gros[13][14]
- 1967 - Postdoctoral fellowship at California Institute of Technology with Robert L. Sinsheimer[15]
- 1967-1982 - ANU Senior Lecturer[16]
- 1983-1996 - ANU Reader[16]
- 1996 - early retirement and position as Research Fellow[16]
References
- ↑ Dalgarno, L.; Shine, J. (31 October 1973). "Conserved Terminal Sequence in 18S rRNA May Represent Terminator Anticodons". Nature New Biology. 245 (148): 261–262. doi:10.1038/newbio245261a0. ISSN 0090-0028. PMID 4202225.
- ↑ "The Shine-Dalgarno sequence - the beginnings of biotechnology | ANU Research School of Biology". biology.anu.edu.au. Retrieved 2021-04-06.
- ↑ Wednesday, 17 November 2010 Carl HolmABC (2010-11-17). "Genetech pioneer awarded science prize". www.abc.net.au. Retrieved 2021-04-06.
- ↑ Dalgarno, L.; Hird, F. J. R. (1960-08-01). "Increase in the process of accumulation of amino acids in carrot slices with prolonged aerobic washing". Biochemical Journal. 76 (2): 209–215. doi:10.1042/bj0760209. ISSN 0306-3283. PMC 1204694. PMID 13813809.
- ↑ Dalgarno, L.; Birt, L. M. (April 1962). "Preparation and properties of a mitochondrial fraction from carrot tissue". The Biochemical Journal. 83 (1): 195–202. doi:10.1042/bj0830195. ISSN 0264-6021. PMC 1243527. PMID 16748945.
- ↑ Dalgarno, L; Birt, Lm (1962-04-01). "Aspects of malate metabolism by slices and mitochondria from carrot tissue". Biochemical Journal. 83 (1): 202–211. doi:10.1042/bj0830202. ISSN 0006-2936. PMC 1243528. PMID 16748947.
- ↑ Dalgarno, L; Birt, Lm (1963-01-01). "The activities of some particulate and non-particulate oxidative enzymes in carrot tissue". Biochemical Journal. 86 (1): 46–56. doi:10.1042/bj0860046. ISSN 0006-2936. PMC 1201709. PMID 14024732.
- ↑ Dalgarno, L; Birt, Lm (1963-06-01). "Free fatty acids in carrot-tissue preparations and their effect on isolated carrot mitochondria". Biochemical Journal. 87 (3): 586–596. doi:10.1042/bj0870586. ISSN 0006-2936. PMC 1202005. PMID 14024731.
- ↑ Horton, E.; Liu, S.-L.; Dalgarno, L.; Martin, E. M.; Work, T. S. (17 October 1964). "Development of Ribonucleic Acid Polymerase in Cells Infected with Encephalomyocarditis Virus and the Synthesis of Single- and Double-Stranded RNA by the Isolated Polymerase". Nature. 204 (4955): 247–250. Bibcode:1964Natur.204..247H. doi:10.1038/204247a0. ISSN 0028-0836. PMID 14212417. Unknown parameter
|s2cid=ignored (help) - ↑ Dalgarno, L; Martin, E.M (July 1965). "Studies on EMC viral RNA synthesis and its localization in infected krebs ascites cells". Virology. 26 (3): 450–465. doi:10.1016/0042-6822(65)90008-5. PMID 14319717.
- ↑ Dalgarno, L.; Martin, E.M.; Liu, S.-L.; Work, T.S. (January 1966). "Characterization of the products formed by the RNA polymerases of cells infected with encephalomyocarditis virus". Journal of Molecular Biology. 15 (1): 77–91. doi:10.1016/S0022-2836(66)80210-3. PMID 4287898.
- ↑ Dalgarno, L.; Cox, R.A.; Martin, E.M. (18 April 1967). "Polyribosomes in normal Krebs 2 ascites tumor cells and in cells infected with encephalomyocarditis virus". Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis. 138 (2): 316–328. doi:10.1016/0005-2787(67)90492-3. PMID 4292778.
- ↑ Dalgarno, L.; Gros, F. (March 1968). "Completion of ribosomal particles in E. coli during inhibition of protein synthesis". Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis. 157 (1): 52–63. doi:10.1016/0005-2787(68)90263-3. PMID 4868250.
- ↑ Dalgarno, L.; Gros, F. (1968-03-18). "RNA synthesis in "relaxed" and "stringent" Escherichia coli. Breakdown of performed ribonucleoprotein particles and subsequent RNA synthesis". Biochimica et Biophysica Acta. 157 (1): 64–75. ISSN 0006-3002. PMID 4868547.
- ↑ Dalgarno, L.; Sinsheimer, R. L. (August 1968). "Process of infection with bacteriophage phiX174. XXIV. New type of temperature-sensitive mutant". Journal of Virology. 2 (8): 822–829. doi:10.1128/JVI.2.8.822-829.1968. ISSN 0022-538X. PMC 375696. PMID 4883013.
- ↑ 16.0 16.1 16.2 (PDF) http://biology-assets.anu.edu.au/CMS/FileUploads/file/Newsletter/Fyfe%20Bygrave%20all.pdf. Unknown parameter
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Further reading
Category:1935 births
Category:Living people
Category:Australian scientists
Category:Australian scientist stubs
Category:Geneticists
Category:Biologists
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