Lyprinol
Lyprinol is a natural marine extract comprising a unique combination of lipid groups and omega-3 polyunsaturated fatty acids. It is extracted under a patented process from the New Zealand green-lipped mussel. Lyprinol is a health or dietary supplement with anti-inflammatory action which assists in the maintenance of healthy airways and breathing passages and also provides relief from joint swelling and arthritis.[1]
Clinical studies have demonstrated that Lyprinol is a modulator of the LOX lipoxygenases pathways, effectively reducing the damaging effects of inflammation from arthritis, asthma and other inflammatory disorders.[citation needed]
Lyprinol (i) causes no gastro-intestinal toxicity as is the case for Non-Steroidal Anti-Inflammatory Drugs ("NSAIDs"), (ii) does not affect blood platelet aggregation (blood thinning) as is the case for fish oils and other omega-3 polyunsaturated fatty acids.
Lyprinol comprises a combination of over 12 omega-3 polyunsaturated fatty acids and anti-oxidants (mostly carotenoids).
In animal studies, Lyprinol was between 50 and 200 times more active than fish or seed oils.[citation needed] A double-blind, placebo-controlled study was conducted on patients with knee osteoarthritis at the Queen Mary Hospital of the University of Hong Kong. After 6–8 weeks, when compared with the placebo group, patients taking Lyprinol had much less pain and their global score– including "quality of life"– was significantly improved.[2][dead link][unreliable source?]
Another double-blind, placebo-controlled study addressed mild-to-moderate adult asthmatics. It was designed at the Royal Brompton Hospital of London, UK (Prof. Peter Barnes). Professor Barnes and Professor A. Emelyanov conducted a study at the Hospital Therapeutic Clinic of the Pavlov Medical University in St. Petersburg, Russia. In the Lyprinol group, there was a significant decrease in day time wheeze, use of the relief metered-dose inhaler, concentration of exhaled H2O2 (a marker of inflammation), and an increase in morning peak expiratory flow when compared to the placebo group. There was no significant side effects reported. The authors concluded that Lyprinol may have some beneficial effect in patients with atopic asthma.[3]
Many other studies have confirmed the safety and efficacy of Lyprinol for a number of inflammatory conditions: diverse forms of arthritis, premenstrual and menstrual pain (without increased bleeding), some inflammatory skin conditions, etc.[citation needed] Large controlled studies are currently being conducted (2006) exploring the efficacy and safety of Lyprinol in children with asthma (New Zealand) and in patients with chronic obstructive pulmonary disease (COPD) (Denmark).[citation needed]
In all studies, the recommended dosage has been 4 Lyprinol capsules/day (to be taken after meals) for 2–3 months, then 2 Lyprinol capsules/day for 2–3 months followed by 1-2 Lyprinol capsules/day for several months.
Cautions and side effects[edit]
Lyprinol is extracted from New Zealand green-lipped mussels harvested in waters near Nelson, New Zealand. The New Zealand green lipped mussel is a shellfish. Shellfish allergies can be caused by proteins in seafood. Since there is no protein extracted with the Lyprinol oil, the risk of shellfish allergy from taking Lyprinol can be ruled out and none to date has been reported.[citation needed] However, as in all cases, it is advisable to see your healthcare professional. Lyprinol may very rarely cause mild diarrhoea, nausea or flatulence.
References[edit]
- ↑ Cho SH, Jung YB, Seong SC, Park HB, Byun KY, Lee DC, Song EK, Son JH (June 2003). "Clinical efficacy and safety of Lyprinol, a patented extract from New Zealand green-lipped mussel (Perna Canaliculus) in patients with osteoarthritis of the hip and knee: a multicenter 2-month clinical trial". European Annals of Allergy and Clinical Immunology. 35 (6): 212–6. PMID 12872680.
- ↑ Lau CS, Chiu PK, Chu EM, CHeng IY, Tang WM, Man RY, Halperin GM (2004). "Treatment of knee osteoarthritis with Lyprinol, lipid extract of the green-lipped mussel – a double- blind placebo-controlled study". Progress in Nutrition. 6 (1): 17–34.[dead link]
- ↑ Emelyanov A, Fedoseev G, Krasnoschekova O, Abulimity A, Trendeleva T, Barnes PJ (September 2002). "Treatment of asthma with lipid extract of New Zealand green-lipped mussel: a randomised clinical trial". The European Respiratory Journal. 20 (3): 596–600. doi:10.1183/09031936.02.02632001. PMID 12358334. Unknown parameter
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Further reading[edit]
- Halpern, Georges M. (2005). The Inflammation Revolution: A Natural Solution for Arthritis, Asthma & Other Inflammatory Disorders. Garden City Park, New York: Square One Publishers. ISBN 978-0-7570-0283-0. OCLC 60558812. Search this book on
External links[edit]
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