Mechanobiology Institute
The Mechanobiology Institute (MBI) at the National University of Singapore (NUS), is dedicated to understanding the emerging scientific field of mechanobiology.[1]
The research institute was established in 2009 under the scientific leadership of two prominent biologists - Prof Michael Sheetz and Prof Paul Matsudaira.
History and funding[edit]
MBI had its beginnings in 2006 as the RCE (Research Centre of Excellence) in Mechanobiology, which was housed in the Brenner Centre for Molecular Medicine at NUS. The RCE was provided the infrastructure to support five laboratories, with approximately 50 researchers. In April 2009, with a commitment from the National Research Foundation[2] and Singapore Ministry of Education of S$150 million over 10 years, the Mechanobiology Institute was established within the newly-built T-lab building at the NUS Kent Ridge campus, where it is located today.[3]
'Open lab' concept[edit]
To encourage interdisciplinary collaboration,[4] the MBI adopts an 'open lab' concept, where common benches are shared by researchers from different labs. Aside from this common laboratory space, lab operations and supplies are also centrally managed by a team of dedicated staff.[5]
Research[edit]
Research in MBI is structured around the following research programmes:
- Molecular Mechanics of Mechanotransduction
- Cell-Matrix and Cell-Cell Mechanotransduction
- Mechanotransduction in Tissues
- Technological Innovation for Mechanobiology
Each programme approaches mechanobiology from a distinct perspective.
Graduate Program[edit]
The MBI hosts a highly competitive postgraduate program with the National University of Singapore, leading to PhDs in Mechanobiology.[6]
References[edit]
- ↑ Wolf, S.J.; Low, B.C.; Hew, C.L. (2017). "Chapter 25: The Mechanobiology Institute — Defining a New Field of Science". World Scientific Series on Singapore's 50 Years of Nation-Building, 50 Years of Science in Singapore: 435–451. doi:10.1142/10057. ISBN 978-981-314-088-2.
- ↑ "Singapore National Research Foundation, Mechanobiology". 2021-02-20. Retrieved 2021-05-20.
- ↑ "NUS Campus Map". www.nus.edu.sg/osa/orientation/101/navigating-in-nus.
- ↑ Sheetz, M.P. (2014). "Can small institutes address some problems facing biomedical researchers?". Mol. Biol. Cell. 25 (21): 3267–3269. doi:10.1091/mbc.E14-05-1017. PMID 25360047. Unknown parameter
|s2cid=ignored (help) - ↑ "MBI Laboratories". www.mbi.nus.edu.sg.
- ↑ "MBI's PhD Programme in Mechanobiology". www.mbi.nus.edu.sg.
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