MethMotif

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MethMotif
MethMotif Database
Content
DescriptionAn integrative cell-specific database of transcription factor binding motifs coupled with DNA methylation profiles
Data types
captured
Eukaryotic transcription factors, their binding sites along with DNA methylation levels
Organismseukaryotes
Contact
Laboratory"Touati Benoukraf lab".
AuthorsQuy Xiao Xuan Lin
Primary citationLin, Q. et al. (2018)[1]
Release date2018
Access
Website"MethMotif".

MethMotif is an integrative cell-specific database of transcription factor binding motifs coupled with DNA methylation profiles. Based on the combination of ChIP-seq and whole genome bisulfite sequencing datasets, MethMotif serves as a two-dimensional transcription factor binding site (TFBS) database that records TFBS Position Weight Matrices along with cell type specific CpG methylation information. The first version of MethMotif database was introduced in 2018.

Availability[edit]

MethMotif is an academic and open source database under GPL licence and available at http://bioinfo-csi.nus.edu.sg/methmotif/.

References[edit]

  1. Lin, Quy Xiao Xuan; Sian, Stephanie; An, Omer; Thieffry, Denis; Jha, Sudhakar; Benoukraf, Touati (31 October 2018). "MethMotif: an integrative cell specific database of transcription factor binding motifs coupled with DNA methylation profiles". Nucleic Acids Research. doi:10.1093/nar/gky1005.

MethMotif[edit]

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