MethMotif
| Content | |
|---|---|
| Description | An integrative cell-specific database of transcription factor binding motifs coupled with DNA methylation profiles |
| Data types captured | Eukaryotic transcription factors, their binding sites along with DNA methylation levels |
| Organisms | eukaryotes |
| Contact | |
| Laboratory | "Touati Benoukraf lab". |
| Authors | Quy Xiao Xuan Lin |
| Primary citation | Lin, Q. et al. (2018)[1] |
| Release date | 2018 |
| Access | |
| Website | "MethMotif". Archived from the original on 2019-10-29. Retrieved 2018-11-26. |
MethMotif is an integrative cell-specific database of transcription factor binding motifs coupled with DNA methylation profiles. Based on the combination of ChIP-seq and whole genome bisulfite sequencing datasets, MethMotif serves as a two-dimensional transcription factor binding site (TFBS) database that records TFBS Position Weight Matrices along with cell type-specific CpG methylation information. The first version of the MethMotif database was introduced in 2018.
Availability
MethMotif is an academic and open-source database under GPL licence and available at http://bioinfo-csi.nus.edu.sg/methmotif/ Archived 2019-10-29 at the Wayback Machine.
References
- ↑ Lin, Quy Xiao Xuan; Sian, Stephanie; An, Omer; Thieffry, Denis; Jha, Sudhakar; Benoukraf, Touati (31 October 2018). "MethMotif: an integrative cell-specific database of transcription factor binding motifs coupled with DNA methylation profiles". Nucleic Acids Research. doi:10.1093/nar/gky1005.
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MethMotif
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