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Microbiological Massacre of 1917

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Microbiological Massacre of 1917
Date1917
LocationPasteur Institute, Paris, France
TypeScientific discovery
CauseBacterial lysis caused by bacteriophages
ParticipantsFélix d'Hérelle

The Microbiological Massacre of 1917 was the first documented case of mass bacterial destruction by viruses known as bacteriophages. This phenomenon was observed by microbiologist Félix d'Hérelle at the Pasteur Institute in Paris during studies on dysentery.

D'Hérelle noticed that an invisible agent in filtered stool samples from dysentery patients was capable of eliminating the bacteria responsible for the disease. He named this agent a bacteriophage, meaning "bacteria eater." This event marked the beginning of research into the use of viruses to combat bacterial infections.

Discovery

In 1917, Félix d'Hérelle conducted experiments to understand the cause of the bacterial lysis observed in cultures of Shigella, the bacterium responsible for dysentery. He filtered samples from infected patients and found that when the filtrate was added to bacterial cultures, the colonies were rapidly destroyed[1].

Impact on microbiology

The discovery of bacteriophages revolutionized microbiology and paved the way for research into phage therapy, an alternative to antibiotics for treating resistant bacterial infections[2].

See also

References



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